Publications
*equal contribution
Narula, J.G. and Wignall, S.M. (2024). “Polo-like kinase I prevents excess microtubule polymerization in C. elegans oocytes to ensure faithful meiosis”, bioRxiv 2024.08.03.606476.
Czajkowski, E.R., Zou, Y., Divekar, N.S., and Wignall, S.M. (2024). “The doublecortin-family kinase ZYG-8DCLK1 regulates microtubule dynamics and motor-driven forces to promote the stability of C. elegans acentrosomal spindles”, In press, PLOS Genetics.
Cavin-Meza, G.*, Mullen, T.J.*, Czajkowski, E., Wolff, I.D., Divekar, N.S., Finkle, J.D., and Wignall, S.M. (2022). “ZYG-9ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis.” PLOS Genetics, 18(11): e1010489.
Horton, H.E., Divekar, N.S., & Wignall, S.M. (2022). “Newfound features of meiotic chromosome organization that promote efficient congression and segregation in Caenorhabditis elegans oocytes.” Molecular Biology of the Cell. mbc.E22-07-0297.
Wolff, I.D., Hollis, J.A., & Wignall, S.M. (2022). “Acentrosomal spindle assembly and maintenance in Caenorhabditis elegans oocytes requires a kinesin-12 nonmotor microtubule interaction domain.” Molecular Biology of the Cell. 33(8):ar71.
Cavin-Meza, G., Kwan, M., & Wignall, S.M. (2022). “Multiple motors cooperate to establish and maintain acentrosomal spindle bipolarity in C. elegans oocyte meiosis.” eLife 11:e72872.
Sue, A.C., Wignall, S.M., Woodruff, T.K., & O’Halloran, T.V. (2022). “Zinc transporters ZIPT-2.4 and ZIPT-15 are required for normal C. elegans fecundity.” Journal of Assisted Reproduction and Genetics. 39(6): 1261-1276.
Mendoza, A.D., Sue, A., Antipode, O., Vogt, S., Woodruff, T.K., Wignall, S.M., & O’Halloran, T.V. (2022). “Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans.” Biology of Reproduction. Apr23:ioac064.
Wolff, I. D., Divekar, N. S., & Wignall, S. M. (2022). “Methods for Investigating Cell Division Mechanisms in C. elegans.” In Mitosis (pp. 19-35). Humana, New York, NY.
Divekar, N. S., Davis-Roca, A. C., Zhang, L., Dernburg, A. F., & Wignall, S. M. (2021). “A degron-based strategy reveals new insights into Aurora B function in C. elegans.” PLOS Genetics. 17(5), e1009567.
Divekar, N. S., Horton H.E. , and Wignall S.M. (2021). “Methods for Rapid Protein Depletion in C. elegans using Auxin‐Inducible Degradation.” Current Protocols 1.2: e16.
Hollis, J. A., Glover, M. L., Schlientz, A. J., Cahoon, C. K., Bowerman, B., Wignall, S. M.*, & Libuda, D. E.* (2020). “Excess crossovers impede faithful meiotic chromosome segregation in C. elegans.” PLOS Genetics, 16(9), e1009001.
Heath, C.M. and Wignall S.M. (2019). “Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis” Molecular Biology of the Cell. 30(14): 1691-1704. (PDF)
Mullen, T.J.*, Davis-Roca A.C.*, and Wignall S.M. (2019). “Spindle assembly and chromosome dynamics during oocyte meiosis.” Current Opinion in Cell Biology. 60: 53-59. (PDF)
Davis-Roca A.C., Divekar N.S., Ng R.K., Wignall S.M. (2018). “Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in C. elegans.” PLOS Genetics. 14(9): e1007626. (PDF)
Mullen, T.J. and Wignall, S.M. (2017). “Interplay between microtubule bundling and sorting factors ensures acentriolar spindle stability during C. elegans oocyte meiosis.” PLOS Genetics. 13(9): e1006986. (PDF)
Davis-Roca, A.C., Muscat, C.C., and Wignall, S.M. (2017). “C. elegans oocytes detect meiotic errors in the absence of canonical end-on kinetochore attachments.” Journal of Cell Biology. 216(5). (PDF)
Mendoza, A.D., Woodruff, T.K., Wignall, S.M., and O’Halloran, T.V. (2017). “Zinc availability during germline development impacts embryo viability in Caenorhabditis elegans.” Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology. 191: 194-202. http://doi.org/10.1016/j.cbpc.2016.09.007
Wolff, I.D., Tran, M.V., Mullen, T.J., Villeneuve, A.M., and Wignall, S.M. (2016). “Assembly of C. elegans acentrosomal spindles occurs without evident MTOCs and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1.” Molecular Biology of the Cell. 27(20): 3122-3131. (PDF)
Muscat, C.C.*, Torre-Santiago, K.M.*, Tran, M.V., Powers, J.A., and Wignall, S.M. (2015). “Kinetochore-independent chromosome segregation driven by lateral microtubule bundles.” eLife.10.7554/eLife.06462. (PDF)
Wignall, S.M. (2015). “Cell Division: Stem Cells Take the Stage.” Current Biology. 25(9): 376-378. (PDF)
Schvarzstein, M., Wignall, S.M., and Villeneuve, A. (2010). “Coordinating cohesion, coorientation and congression during meiosis: Lessons from holocentric chromosomes.” Genes and Development. 24(3): 219-228. (PDF)
Wignall, S.M. and Villeneuve, A. (2009). “Lateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis.” Nature Cell Biology. 11(7): 839-844. (PDF)
Wignall, S.M., Gray, N.S., Chang, Y.T., Juarez, L., Jacob, R., Burlingame, A., Schultz, P.G., and Heald, R. (2004). “Identification of a novel protein regulating microtubule stability using a chemical approach.” Chemistry and Biology. 11(1): 135-146. (PDF)
Wignall, S.M., Deehan, R., Maresca, T., and Heald, R. (2003). “The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts” Journal of Cell Biology. 161(6): 1041-1051. (PDF)
Wignall, S.M., and Heald, R. (2001). “Methods for the study of centrosome-independent spindle assembly in Xenopus extracts.” Methods in Cell Biology. 67: 241-256. (PDF)