Authors | Publication Title | Journal | Year |
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McLaren P.J., Porreca I., Iaconis G., Mok H.P., Mukhopadhyay S., Karakoc E., Cristinelli S., Pomilla C., Bartha I., Thorball C.W., Tough R.H., Angelino P., Kiar C.S., Carstensen T., Fatumo S., Porter T., Jarvis I., Skarnes W.C., Bassett A., DeGorter M.K., Sathya Moorthy M.P., Tuff J.F., Kim E.Y., Walter M., Simons L.M. , Bashirova A., Buchbinder S., Carrington M., Cossarizza A., De Luca A., Goedert J.J., Goldstein D.B., Haas D.W., Herbeck J.T., Johnson E.O., Kaleebu P., Kilembe W., Kirk G.D., Kootstra N.A., Kral A.H., Lambotte O., Luo M., Mallal S., Martinez-Picado J., Meyer L., Miro J.M., Moodley P., Motala A.A., Mullins J.I., Nam K., Obel N., Pirie F., Plummer F.A., Poli G., Price M.A., Rauch A., Theodorou I., Trkola A., Walker B.D., Winkler C.A., Zagury J.F., Montgomery S.B., Ciuffi A., Hultquist J.F. , Wolinsky S.M., Dougan G., Lever A.M.L., Gurdasani D., Groom H., Sandhu M.S., Fellay J. | Africa-specific human genetic variation near CHD1L associates with HIV-1 load | Nature | 2023 |
Soliman S.H.A., Cisneros W.J., Iwanaszko M., Aoi Y., Ganesan S., Walter M., Zeidner J.M., Mishra R.K., Kim E.Y., Wolinsky S.M., Hultquist J.F., Shilatifard A. | Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. | Science Advances | 2023 |
Vandervaart J.P., Inniss N.L., Ling-Hu T., Minasov G., Wiersum G., Rosas-Lemus M., Shuvalova L., Achenbach C.J., Hultquist J.F., Satchell K.J.F., Bachta K.E.R. | Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions. | Microbiology Spectrum | 2023 |
Vaidyanathan A., Taylor H.E., Hope T.J., D'Aquila R.T., Bartom E.T., Hultquist J.F., Peter M.E. | Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1-Induced Cytopathicity | Journal of Virology | 2023 |
Fink E.A., Bardine C., Gahbauer S., Singh I., Detomasi T.C., White K., Gu S., Wan X., Chen J., Ary B., Glenn I., O'Connell J., O'Donnell H., Fajtová P., Lyu J., Vigneron S., Young N.J., Kondratov I.S., Alisoltani A., Simons L.M., Lorenzo-Redondo R., Ozer E.A., Hultquist J.F., O'Donoghue A.J., Moroz Y.S., Taunton J., Renslo A.R., Irwin J.J., García-Sastre A., Shoichet B.K., Craik C.S. | Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors | Protein Science | 2023 |
Ozer E.A., Simons L.M., Adewumi O.M., Fowotade A.A., Omoruyi E.C., Adeniji J.A., Dean T.J., Zayas J, Bhimalli P.P., Ash M.K., Godzik A, Schneider J.R., Mamede J.I., Taiwo B.O., Hultquist J.F., Lorenzo-Redondo R | Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria | Nature Communications | 2022 |
Malikov V., Meade Nathan., Simons L.M. , Hultquist J.F., Naghavi, M.H. | FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression | Cell Reports | 2022 |
Hiatt J., Hultquist J.F., McGregor M.J., Bouhaddou M., Leenay R.T., Simons L.M., Young J.M., Haas P., Roth T.L., Tobin V., Wojcechowskyj J.A., Woo J.M., Rathore U., Cavero D.A., Shifrut E., Nguyen T.T., Haas K.M., Malik H.S., Doudna J.A., May A.P., Marson A., Krogan N.J. | A functional map of HIV-host interactions in primary human T cells. | Nature Communications | 2022 |
Yoh S.M., Mamede J.I., Lau D., Ahn N., Sánchez-Aparicio M.T., Temple J., Tuckwell A., Fuchs N.V., Cianci G.C., Riva L., Curry H., Yin X., Gambut S., Simons L.M., Hultquist J.F., König R., Xiong Y., García-Sastre A., Böcking T., Hope T.J., Chanda S.K. | Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA. | Molecular Cell | 2022 |
Johnson J.R., Crosby D.C., Hultquist J.F., Kurland A.P., Adhikary P., Li D., Marlett J., Swann J., Hüttenhain R., Verschueren E., Johnson T.L., Newton B.W., Shales M., Simon V.A., Beltrao P., Frankel A.D., Marson A., Cox J.S., Fregoso O.I., Young J.A.T., Krogan N.J. | Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling. | Cell Reports | 2022 |
Packard T.A., Schwarzer R., Herzig E., Rao D., Luo X., Egedal J.H., Hsiao F., Widera M., Hultquist J.F., Grimmett Z.W., Messer R.J., Krogan N.J., Deeks S.G., Roan N.R., Dittmer U., Hasenkrug K.J., Greene W.C. | CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. | mBio | 2022 |
Alisoltani A., Jaroszewski L., Godzik A., Iranzadeh A., Simons L.M., Dean T.J., Lorenzo-Redondo R., Hultquist J.F., Ozer E.A. | ViralVar: A Web Tool for Multilevel Visualization of SARS-CoV-2 Genomes. | Viruses | 2022 |
Ling Hu T., Rios Guzman E., Lorenzo-Redondo R., Ozer E.A., Hultquist J.F. | Challenges and Opportunities for Global Genomic Surveillance Strategies in the COVID-19 Era. | Viruses | 2022 |
Cisneros W.J., Cornish D., Hultquist J.F. | Application of CRISPR-Cas9 Gene Editing for HIV Host Factor Discovery and Validation. | Pathogens | 2022 |
Samer S., Thomas Y., Araínga M., Carter C., Shirreff L.M., Arif M.S., Avita J.M., Frank I., McRaven M.D., Thuruthiyil C.T., Heybeli V.B., Anderson M.R., Owen B., Gaisin A., Bose D., Simons L.M., Hultquist J.F., Arthos J., Cicala C., Sereti I., Santangelo P.J., Lorenzo-Redondo R., Hope T.J., Villinger F.J., Martinelli E. | Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo. | JCI Insight | 2022 |
Rios Guzman E., Hultquist J.F.. | Clinical and biological consequences of respiratory syncytial virus genetic diversity. | Therapeutics Advances in Infectious Disease | 2022 |
Reyna M.E., Edward P.R., Ozer E.A., Simons L.M., Hultquist J.F., Lorenzo-Redondo R., Patel A.B., Kociolek L.K. | Incidence and Clinical Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 Infection After Vaccination in Children. | Journal of Pediatrics | 2022 |
Edward P.R., Lorenzo-Redondo R., Reyna M.E., Simons L.M., Hultquist J.F., Patel A.B., Ozer E.A., Muller W.J., Heald-Sargent T., McHugh M., Dean T., Dalal R.M., John J., Manz S.C., Kociolek L.K. | Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort Study. | Journal of the Pediatric Infectious Diseases Society | 2022 |
Lorenzo-Redondo R., Ozer E.A., Hultquist J.F. | Covid-19: is omicron less lethal than delta? | BMJ | 2022 |
Fernandez-de Céspedes M.V., Hoffman H.K., Carter H., Simons L.M., Naing L., Ablan S.D., Scheiblin D.A., Hultquist J.F., van Engelenburg S.B., Freed E.O. | Rab11-FIP1C Is Dispensable for HIV-1 Replication in Primary CD4+ T Cells, but Its Role Is Cell Type Dependent in Immortalized Human T-Cell Lines. | Journal of Virology | 2022 |
Simons L.M., Ozer E.A., Gambut S., Dean T.J., Zhang L., Bhimalli P., Schneider J.R., Mamede J.I., Ison M.G., Karmali R., Gordon L.I., Lorenzo-Redondo R., Hultquist J.F. | De novo emergence of SARS-CoV-2 spike mutations in immunosuppressed patients. | Transplant Infectious Diseases | 2022 |
Ke R., Martinez P.P., Smith R.L., Gibson L.L., Achenbach C.J., McFall S., Qi C., Jacob J., Dembele E., Bundy C., Simons L.M., Ozer E.A., Hultquist J.F., Lorenzo-Redondo R., Opdycke A.K., Hawkins C., Murphy R.L., Mirza A., Conte M., Gallagher N., Luo C.H., Jarrett J., Conte A., Zhou R., Farjo M., Rendon G., Fields C.J., Wang L., Fredrickson R., Baughman M.E., Chiu K.K., Choi H., Scardina K.R., Owens A.N., Broach J., Barton B., Lazar P., Robinson M.L., Mostafa H.H., Manabe Y.C., Pekosz A., McManus D.D., Brooke C.B. | Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution. | Open Forum Infectious Diseases | 2022 |
Agarwal D.K., Hunt A.C., Shekhawat G.S., Carter L., Chan S., Wu K., Cao L., Baker D., Lorenzo-Redondo R., Ozer E.A., Simons L.M., Hultquist J.F., Jewett M.C., Dravid V.P. | Rapid and Sensitive Detection of Antigen from SARS-CoV-2 Variants of Concern by a Multivalent Minibinder-Functionalized Nanomechanical Sensor. | Analytical Chemistry | 2022 |
Lundberg A.L., Lorenzo-Redondo R., Hultquist J.F., Hawkins C.A., Ozer E.A., Welch S.B., Prasad P.V.V., Achenbach C.J., White J.I., Oehmke J.F., Murphy R.L., Havey R.J., Post L.A. | Overlapping Delta and Omicron Outbreaks During the COVID-19 Pandemic: Dynamic Panel Data Estimates. | JMIR Public Health and Surveillance | 2022 |
Mithal L.B., Otero S., Simons L.M., Hultquist J.F., Miller E.S., Ozer E.A., Shanes E.D., Goldstein J.A. | Low-level SARS-CoV-2 viremia coincident with COVID placentitis and stillbirth. | Placenta | 2022 |
Madden P.J., Thomas Y., Blair R.V., Samer S., Doyle M., Midkiff C.C., Doyle-Meyers L.A., Becker M.E., Arif M.S., McRaven M.D., Simons L.M., Carias A.M., Martinelli E., Lorenzo-Redondo R., Hultquist J.F., Villinger F.J., Veazey R.S., Hope T.J. | An immunoPET probe to SARS-CoV-2 reveals early infection of the male genital tract in rhesus macaques. | BioRxiv (preprint) | 2022 |
Selyutina A., Simons L.M., Kirby K.A., Bulnes-Ramos A., Hu P., Sarafianos S.G., Hultquist J.F., Diaz-Griffero F. | TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection | Viruses | 2022 |
Simons, L.M, Lorenzo-Redondo R., Gibson M, Kinch S.L., Vandervaart J.P., Reiser N.L., Eren M., Lux E., McNally E.M., Tambur A.R., Vaughan D.E., Bachta K.E.R., Demonbreun A.R., Satchell K.J.F., Achenbach C.J., Ozer E.A., Ison M.G., Hultquist J.F. | Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults | Open Forum Infectious Diseases | 2022 |
Lundberg A.L., Lorenzo-Redondo R, Ozer E.A., Hawkins C.A., Hultquist J.F., Welch S.B., Prasad P.V.V., Oehmke J.F., Achenbach C.J., Murphy R.L., White J.I., Havey R.J., Post L.A. | Has Omicron Changed the Evolution of the Pandemic? | JMIR Public Health Surveillance | 2022 |
Siddiqui S.M., Bowman K.A., Zhu A.L., Fischinger S, Beger S, Maron J.S., Bartsch Y.C., Atyeo C, Gorman M.J., Yanis A, Hultquist J.F. , Lorenzo-Redondo R, Ozer E.A., Simons L.M., Talj R, Rankin D.A., Chapman L, Meade K, Steinhart J, Mullane S, Siebert S, Streeck H, Sabeti P, Halasa N, Musk E.R., Barouch D.H., Menon A.S., Nilles E.J., Lauffenburger D.A., Alter G. | Serological Markers of SARS-CoV-2 Reinfection. | mBio | 2022 |
Luo Z., Li M., Li T.W., Lv Z., Ye Z., Cisneros W.J., Zhang J., Yuan L., Hultquist J.F., Migueles S.A., Huang L., Zhu J., Jiang W. | Differential Expression of CREM/ICER Isoforms Is Associated with the Spontaneous Control of HIV Infection | mBio. | 2022 |
Ke R, Martinez P.P., Smith R.L., Gibson L.L., Achenbach C.J., McFall S, Qi C, Jacob J, Dembele E, Bundy C, Simons L.M., Ozer E.A., Hultquist J.F., Lorenzo-Redondo R, Opdycke A.K., Hawkins C, Murphy R.L., Mirza A, Conte M, Gallagher N, Luo C.H., Jarrett J, Conte A, Zhou R, Farjo M, Rendon G, Fields C.J., Wang L, Fredrickson R, Baughman M.E., Chiu K.K., Choi H, Scardina K.R., Owens A.N., Broach J, Barton B, Lazar P, Robinson M.L., Mostafa H.H., Manabe Y.C., Pekosz A, McManus D.D., Brooke C.B. | Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveal limited infectious virus shedding and restricted tissue distribution | OFID (in press). | 2022 |
Martin-Sancho L, Lewinski M.K., Pache L, Stoneham C.A., Yin X, Becker M.E., Pratt D, Churas C, Rosenthal S.B., Liu S, Weston S, De Jesus P.D., O'Neill A.M., Gounder A.P., Nguyen C, Pu Y, Curry H.M., Oom A.L., Miorin L, Rodriguez-Frandsen A, Zheng F, Wu C, Xiong Y, Urbanowski M, Shaw M.L., Chang M.W., Benner C, Hope T.J., Frieman M.B., García-Sastre A, Ideker T, Hultquist J.F. , Guatelli J, Chanda S.K. | Functional landscape of SARS-CoV-2 cellular restriction | Molecular Cell | 2021 |
Lorenzo-Redondo R, Nam H.H., Roberts S.C., Simons L.M., Jennings L.J., Qi C, Achenbach C.J., Hauser A.R., Ison M.G., Hultquist J.F., Ozer E.A. | A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways. | EBioMedicine | 2021 |
Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus P.D., Yang C.C., Herbert K.M., Yoh S, Hultquist J.F., García-Sastre A, Chanda S.K. | MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells | Cell Reports | 2021 |
Martin-Sancho L, Tripathi S, Rodriguez-Frandsen A, Pache L, Sanchez-Aparicio M, McGregor M.J., Haas K.M., Swaney D.L., Nguyen T.T., Mamede J.I., Churas C, Pratt D, Rosenthal S.B., Riva L, Nguyen C, Beltran-Raygoza N, Soonthornvacharin S, Wang G, Jimenez-Morales D, De Jesus P.D., Moulton H.M., Stein D.A., Chang M.W., Benner C, Ideker T, Albrecht R.A., Hultquist J.F., Krogan N.J., García-Sastre A, Chanda S.K. | Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy | Nature Microbiology | 2021 |
Chai Q, Li S, Collins M.K., Li R, Ahmad I, Johnson S.F., Frabutt D.A., Yang Z, Shen X, Sun L, Hu J, Hultquist J.F., Peterlin B.M., Zheng Y | HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity | Cell Reports | 2021 |
Kociolek L.K., Patel A.B., Hultquist J.F., Ozer E.A., Simons L.M., McHugh M, Muller W.J., Lorenzo-Redondo R | Viral whole-genome sequencing to assess impact of universal masking on SARS-CoV-2 transmission among pediatric healthcare workers. | Infection Control & Hospital Epidemiology (Epub ahead of print) | 2021 |
Selyutina A, Hu P, Miller S, Simons L.M. , Yu H.J., Hultquist J.F., Lee K, KewalRamani V.N., Diaz-Griffero F. | GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors. | iScience | 2021 |
Edward P.R., Reyna M.E., Daly M.K., Hultquist J.F., Muller W.J., Ozer EA, Lorenzo-Redondo R, Seed P.C., Simons L.M., Sheehan K, Staples J, Kociolek | Screening Students and Staff for Asymptomatic Coronavirus Disease 2019 in Chicago Schools | The Journal of Pediatrics | 2021 |
Edward P.R., Lorenzo-Redondo R, Reyna M.E., Simons L.M., Hultquist J.F., Patel A.B., Ozer E.A., Muller W.J., Heald-Sargent T, McHugh M, Dean T.J., Dalal R.M., John J, Manz S.C., Kociolek L.K. | Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort Study | medRxiv (preprint) | 2021 |
Hiatt J, Cavero D.A., McGregor M.J., Zheng W, Budzik J.M., Roth T.L., Haas K.M., Wu D, Rathore U, Meyer-Franke A, Bouzidi M.S., Shifrut E, Lee Y, Kumar V.E., Dang E.V., Gordon D.E., Wojcechowskyj J.A., Hultquist J.F., Fontaine K.A., Pillai S.K., Cox J.S., Ernst J.D., Krogan N.J., Marson A | Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins | Cell Reports | 2021 |
Agarwal D.K., Nandwana V, Henrich S.E., Josyula V.P.V.N., Thaxton C.S., Qi C, Simons L.M., Hultquist J.F., Ozer E.A., Shekhawat G.S., Dravid V.P.. | Highly sensitive and ultra-rapid antigen-based detection of SARS-CoV-2 using nanomechanical sensor platform | Biosensors and Bioelectronics | 2021 |
Demonbreun A.R., McDade T.W., Pesce L, Vaught L.A., Reiser N.L., Bogdanovic E, Velez M.P., Hsieh R.R., Simons L.M., Saber R, Ryan D.T., Ison M.G., Hultquist J.F., Wilkins J.T., D'Aquila R.T., Mustanski B, McNally E.M. | Patterns and persistence of SARS-CoV-2 IgG antibodies in Chicago to monitor COVID-19 exposure | JCI Insight | 2021 |
Lorenzo-Redondo R, Ozer EA, Achenbach CJ, D'Aquila RT, Hultquist J.F. | Molecular epidemiology in the HIV and SARS-CoV-2 pandemics | Current Opinion in HIV and AIDS | 2021 |
Selyutina A., Simons L.M., Bulnes-Ramos A., Hultquist J.F., & Diaz Griffero, F. | Restriction of HIV-1 viruses bearing the capsid mutation N74D by human TRIM5a in lymphocytes is due to a loss of Cyclophilin A protection. | Cell Reports. | 2020 |
Hiatt J.*, Hultquist J.F.*, Leenay R.T., Rheinemann L., McGregor M.J., Haas P., Roth T.L., Wojcechowskyj J.A., Sperber H., Tobin V., Woo J., Rathore U., Cavero D., Nguyen T.,Pillai S., Sundquist W., May A.P., Marson A., & Krogan N.J. | A Functional Map of HIV-Host Interactions in Primary CD4+ T Cells. | Nature Immunology. | 2020 |
Selyutina A., Persaud M., Simons L.M., Bulnes-Ramos A., Buffone C., Martinez-Lopez A., Scoca V., Di Nunzio F., Hiatt J., Marson A., Krogan N.J., Hultquist J.F., & Diaz Griffero, F. | Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking TRIM5a Binding to the Viral Core. | Cell Reports. 30: 3766-3777. | 2020 |
Du Y., Hultquist J.F., Zhou Q., Olson A., Tseng Y., Zhang T., Hong M., Tang K., Chen L., Meng X., McGregor M.J., Dai L., Gong D., Martin-Sancho L., Chanda S., Li X., Bensenger S., Krogan N.J., & Sun R. | mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1. | Nature Communications. 11: 2449. PMID: 32415096. | 2020 |
Eckhardt M.*, Hultquist J.F.*, Kaake R., Huttenhain R., & Krogan, N.J. | A Systems Approach to Infectious Disease. | Nature Reviews Genetics. 21: 339-354. PMID: 32060427. | 2020 |
Leenay R.T., Aghazadeh A., Hiatt J., Tse D., Roth T., Apathy R., Shifrut E., Hultquist J.F., Krogan N.J., Wu Z., Cirolia G., Canaj H., Leonetti M.D., Marson A., May A.P., & Zou J. | Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells. | Nature Biotechnology. 37: 1034-1037. PMID: 31359007. | 2019 |
Huttenhain R., Xu J., Burton L.A., Gordon D., Hultquist J.F., Johnson J.R., Satkamp L., Hiatt J., Rhee D.Y, Baek K., Crosby D.C., Frankel A.D., Marson A., Harper J.W., Alpi A.F., Schulman B.A., Gross J.D., & Krogan N.J. | ARIH2 is a Vif-dependent Regulator of CUL5-mediated APOBEC3G Degradation in HIV Infection. | Cell Host and Microbe. S1931-3128: 30253-30257. PMID: 31253590. | 2019 |
Hultquist J.F., Hiatt J., Schumann K., McGregor M.J., Roth T.L., Haas P., Doudna J., Marson A., & Krogan, N.J. | CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions. | Nature Protocols. 14: 1-27. PMID: 30559373. | 2019 |
Batra J.*, Hultquist J.F.*, Liu D., Shtanko O., Von Dollen J., Satkamp L., Jang G.M., Luthra P., Schwarz T.M., Small G.I., Arnett E., Anantpadma M., Reyes A., Leung D.W., Kaake R., Haas P., Schmidt C.B., Schlesinger L.S., LaCount D.J., Davey R.A., Amarasinghe G.K., Basler C.F., & Krogan N.J. | Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication. | Cell. 175: 1917-1930. PMID: 30550789. | 2018 |
Liu D., Small G., Hultquist J.F., Krogan N.J., Batra J., Basler C., Leung D.W., & Amarasinghe G.K. | Biochemical and structural characterization of a host protein that binds Ebola VP30. | Journal of Immunology. 200: S182.32. | 2018 |
Zhao N., Sebastiano V., Moshkina N., Mena N., Hultquist J.F., Jimenez-Morales D., Ma Y., Rialdi A., Albrecht R., Fenouil R., Sanchez-Aparicio M., Ayllon J., Ravisankar S., Haddad B., Ho J.S.Y., Low D., Jin J., Yurchenko V., Prinja R.K., Tarakhovsky A., Squatrito M., Pinto D., Allette K., Byun M., Smith M.L., Sebra R., Guccione E., Tumpey T., Krogan N.J., Greenbaum B., van Bakel H., Garcia-Sastre A., & Marazzi, I. | Influenza virus infection causes global RNAPII termination defects. | Nature Structural & Molecular Biology. 25: 885–893. PMID: 30177761. | 2018 |
Chen S., Jang G.M., Hüttenhain R., Gordon D.E., Du D., Newton B.W., Johnson J.R., Hiatt J., Hultquist J.F., Johnson T.L., Liu Y., Burton L.A., Ye J., Reichermeier K.M., Stroud R.M., Marson A., Debnath J., Gross J.D., & Krogan N.J. | CRL4 AMBRA1 targets ElonginC for ubiquitination and degradation to modulate CRL5 signaling. | EMBO. e97508. PMID: 30166453. | 2018 |
Dornfield D., Dudek A., Vausselin T., Gunther S., Hultquist J.F., Giese S., Khokhlova-Cubberley D., Chew Y.C., Krogan N.J., Garcia-Sastre A., Schwemmle M., & Shaw M.L. | SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses. | Scientific Reports. 8: 2092. PMID: 29391557 | 2018 |
Binning J., Smith A., Hultquist J.F., Craik C.S., Caretta N., Campbell M.G., Burton L., La Greca F., McGregor M.J., Ta H.M., Bartholomeeusen K., Peterlin B.M., Krogan N.J., Sevillano N., Cheng Y., & Gross J.D. | Fab-based inhibitors reveal ubiquitin independent functions of HIV Vif neutralization of APOBEC3 restriction factors. | PLoS Pathogens. 14: e1006830. PMID: 29304101. | 2018 |
Rialdi A., Hultquist J.F., Jimenez-Morales D., Peralta Z., Campisi L., Fenouil R., Moshkina N., Wang Z., Laffleur B., Kaake R., McGregor M., Haas K., Pefanis E., Albrecht R.A., Pache L., Chanda S., Jen J., Ochando J., Byun M., Basu U., Garcia-Sastre A., Krogan N.J., van Bakel H., & Marazzi, I. | The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. | Cell. 169: 679-692. PMID: 28475896. | 2017 |
Rauch B.J., Silvis M.R., Hultquist J.F., Waters C., McGregor M.J., Krogan N.J., & Bondy-Demony J. | Inhibition of CRISPR-Cas9 with Bacteriophage Proteins. | Cell. 168: 150-158. PMID: 28041849. | 2017 |
Park R.*, Wang T.*, Koundakjian D., Hultquist J.F., LaMothe-Molina P., Monel B., Schumann K., Yu H., Krupzcak K.M., Garcia-Beltran W., Piechocka-Trocha A., Krogan N.J., Marson A., Sabatini D., Lander E., Hacohen N., & Walker, B.D. | A Genome-Wide CRISPR Screen Reveals a Remarkably Restricted Set of HIV Host Dependency Factors. | Nature Genetics. 2016 Dec 19. doi: 10.1038/ng.3741. PMID: 27992415. | 2016 |
Hultquist J.F.*, Schumann K.*, Woo J., Manganaro L., Simon V., Doudna J., Krogan N.J., & Marson, A. | A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells. | Cell Reports. 17: 1438-1452. PMID: 27783955. | 2016 |
Heaton N.S., Moshkina N., Fenouil R., Gardner T.J., Aguirre S., Shah P.S., Zhao N., Manganaro L., Hultquist J.F., Noel J., Sachs D.H., Hamilton J., Leon P.E., Chawdury A., Tripathi S., Melegari C., Campisi L., Hai R., Metreveli G., Gamarnik A.V., García-Sastre A., Greenbaum B., Simon V., Fernandez-Sesma A., Krogan N.J., Mulder L.C., van Bakel H., Tortorella D., Taunton J., Palese P., & Marazzi I. | Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. | Immunity. 44: 46-58. PMID: 26789921. | 2016 |
Kane J.R., Hultquist J.F., Stanley D.J., Binning J.M., Johnson J.R., Johnson T., Newton W., Franks-Skiba K., Harris R.S., Gross J.D., & Krogan, N.J. | Lineage-Specific Hijacking of Non-Canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Lentiviral Vif Anti-APOBEC3 Activity. | Cell Reports. 11: 1236-1250. PMID: 25981045. | 2015 |
Refsland E.W., Hultquist J.F., Luengas E.M., Ikeda T., Shaban N.M., Law E.K., Brown W.L., Emerman M., & Harris, R.S. | Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity. | PLoS Genetics. 10: e1004761. PMID: 25411794. | 2014 |
Land A.M., Shaban N.M., Evans L., Hultquist J.F., Albin J.S., & Harris, R.S. | APOBEC3F Determinants of HIV-1 Vif Sensitivity. | Journal of Virology. 88: 12923-12927. PMID: 25142588. | 2014 |
McDougle, R.M., Hultquist J.F., & Harris, R.S. | D316 is Critical for the Enzymatic Activity and HIV-1 Restriction Potential of Human and Rhesus APOBEC3B. | Virology. 441: 31-39. PMID: 23542011. | 2013 |
Harris R.S., Hultquist J.F., & Evans D.T. | The Restriction Factors of Human Immunodeficiency Virus. | J. Biol. Chem. 287: 40875-40883. PMID: 23043100. | 2012 |
Hultquist J.F., McDougle R.M., Anderson B.A., & Harris R.S. | HIV Type 1 Viral Infectivity Factor and the RUNX Transcription Factors Interact with Core Binding Factor β on Genetically Distinct Interfaces. | ARHR. 28: 1543-1551. PMID: 22725134. | 2012 |
Refsland E.W., Hultquist J.F., & Harris R.S. (2012). | Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n. | PLoS Pathogens. 8: e1002800. PMID: 22807680. | 2012 |
Lackey L., Demorest Z.L., Land A.M., Hultquist J.F., Brown W.L., & Harris R.S. | APOBEC3B and AID Have Similar Nuclear Import Mechanisms. | J. Mol. Biol. 419: 301-314. PMID: 22446380. | 2012 |
Hultquist J.F., Binka M., LaRue R.S., Simon V., & Harris R.S. | Vif Proteins of Human and Simian Immunodeficiency Viruses Require Cellular CBFβ to Degrade APOBEC3 Restriction Factors. | Journal of Virology. 86: 2874-2877. PMID: 22205746. | 2012 |
Jäger S.*, Kim D.*, Hultquist J.F.*, Shindo K., LaRue R., Kwon E., Li M., Anderson B., Yen L., Stanley D., Mahon C., Kane J., Franks-Skiba K., Cimermancic P., Burlingame A., Sali A., Craik C., Harris R.S., Gross J., & Krogan N. | Vif Hijacks CBFβ to Degrade APOBEC3G and Promote HIV-1 Infection. | Nature. 481: 371-375. PMID: 22190037. | 2012 |
Hultquist J.F., Lengyel J.A., LaRue R.S., Lackey L.L., Brown W.L., & Harris R.S. | Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity to Restrict Vif-deficient HIV-1. | Journal of Virology. 85: 11220-11234.¬ PMID: 21835787. | 2011 |
Albin J.S., Hache G., Hultquist J.F., Brown W.L., & Harris R.S. | Long term Restriction by APOBEC3F Selects Human Immunodeficiency Type 1 Variants with Restored Vif Function. | Journal of Virology. 84: 10209-10219. PMID: 20686027. | 2010 |
Hultquist J.F. & Harris R.S. | Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. | Future Virology. 4: 605-619. PMID: 20174454. | 2009 |
Hultquist J.F. & Dorweiler J.E. | Feminized Tassels of Maize mop1 and ts1 Mutants Exhibit Altered Levels of miR156 and Specific SBP-box Genes. | Planta. 229: 99-113. PMID: 18800226. | 2008 |