Recent Publications

  • Meneghini M, Tambur AR. HLA-DQ antibodies in alloimmunity, what makes them different? Curr Opin Organ Transplant 2023, ePub PMID 37219535
  • Lefaucheur C, Louis K, Morris AB, Taupin JL, Nickerson P, Tambur AR, Gebel HM, Reed EF; STAR 2022 Working Group. Clinical recommendations for posttransplant assessment of anti-HLA (Human Leukocyte Antigen) donor-specific antibodies: A Sensitization in Transplantation: Assessment of Risk consensus document. AJT 2023 23(1):115-132. PMID 36695614
  • Tambur AR, et al Sensitization in Transplantation: Assessment of Risk 2022 Working Group Meeting Report. AJT 2023; 23(1):133-149 PMID 36695615
  • Tambur AR, Audry B, Glotz D, Jacquelinet C. Improving equity in kidney transplant allocation policies through a novel genetic metric: the matched donor potential. AJT 2023; 23(1):45-54 PMID 36695620
  • Hod-Dvorai R, Lee R, Muluhngwi P, Raijmakers M, Shetty A, Tambur AR, Ison MG. Development of De Novo Donor Specific Antibodies in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction. Transpl Infect Dis. 2022 Nov 22:e13993. doi: 10.1111/tid.13993. Online ahead of print.PMID: 36413505
  • Isaacson D, Schold JD, Gmeiner MW, Copley HC, Kosmoliaptsis V, Tambur AR. HLA-DQ mismatches lead to more unacceptable antigens, greater sensitization, and increased disparities as demonstrated in repeat transplant candidates. J Am Soc Nephrol. 2022 Dec;33(12):2293-2305. doi: 10.1681/ASN.2022030296. Epub 2022 Aug 31.PMID: 36450598
  • Tambur AR, Das R. Can we use eplets (or molecular) mismatch load analysis to improve organ allocation: The hope and the hype. 2023 1:107(3):605-615. PMID: 36163639
  • Tambur AR, Schinstock C. Clinical Utility of Serial Serum Dilutions for HLA antibody Interpretation. HLA in press
  • Simons LM, Lorenzo-Redondo R, Gibson M, Kinch SL, Vandervaart JP, Reiser NL, Eren M, Lux E, McNally EM, Tambur AR, Vaughan DE, Bachta KER, Demonbreun AR, Satchell KJF, Achenbach CJ, Ozer EA, Ison MG, Hultquist JF. Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults. Open Forum Infect Dis. 2022 Feb 14;9(3):ofac027. doi: 10.1093/ofid/ofac027. eCollection 2022 Mar.
  • Saleem N, Das R, Tambur AR. Molecular Histocompatibility Beyond Tears: The Next Generation Version. Hum Immunol, in press, https://doi.org/10.1016/j.humimm.2021.12.005
  • Tambur AR, Kosmoliaptsis V, Claas FHJ, Mannon RB, Nickerson P, Naesens M. Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen-matching priorities to improve transplant outcomes? An expert review and recommendations. Kidney Int. 2021 Nov;100(5):1012-1022. doi: 10.1016/j.kint.2021.06.026. PMID: 34246656 Schinstock C, Tambur AR. Apples, oranges, and anything in between: In search of the best desensitization therapy. Am J Transplant 2021 21(12) 3824-3826 PMID: 34416097Simons LM, Lorenzo-Redondo R, Gibson M, Kinch SL, Vandervaart JP, Reiser NL, Eren M, Lux E, McNally E, Tambur AR, Vaugha DE, Bachta KR, Demonbreun AR, Satchell KJF, Achenbach CJ, Ozer EA, Ison MG, Hultquist JF. Assessment and modeling of COVID-19 outcomes in a longitudinal cohort of hospitalized adults. MedRVix 2021  org/10.1101/2021.07.02.21259665; Open Forum Infectious Diseases https://doi.org/10.1093/ofid/ofac027
  • Garcia-Sanchez C, Castillas-Abundis MA, Pinelli DF, Tambur AR, Hod-Dvorai R, Impact of SIRPα Polymorphism on Transplant Outcomes in HLA-identical Living Donor Kidney Transplantation. Clinical Transplantation.in press doi: 10.1111/ctr.14406. Online ahead of print.PMID: 34180101
  • Rachel M Engen, Anat R Tambur. Accurate eplet identification is necessary for accurate risk assessment. AJT 2021 21(10): 3540org/10.1111/ajt.16612 PMID: 33866684
  • Schinstock CA, Stegall MD, Tambur AR. Current Approaches to Desensitization in Solid Organ Transplantation. Frontiers in Immunology, section Alloimmunity and Transplantation. 2021 11;12:686271 doi: 10.3389/fimmu.2021.686271 PMID: 34046044 
  • Asano Y, Daccache J, Jain D, Ko K, Kinloch A, Veselits M, Wolfgeher D, Chang A, Josephson M, Cunningham P, Tambur A, Khan AA, Pillai S, Chong AS, Clark MR. Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection. Nature communications 2021, 12:4372  
  • Engen RM, Jedraszko AM, Conciatori MA, Tambur AR. (2021) Substituting imputation of HLA antigens for high resolution HLA typing: Evaluation of a multiethnic population and implications for molecular mismatch evaluation for clinical decision making. Am J Transplant. 21(1):344-352.
  • Maguire CH, Schinstock CA, Tambur AR. (2020). Measuring human leukocyte antigen alloantibodies: beyond a binary decision. Curr Opin Organ Transplant. 25(6):529-535
  • Tambur AR, Campbell P, Chong AS, Feng S, Ford ML, Gebel H, Gill RG, Kelsoe G, Kosmoliaptsis V, Mannon RB, Mengel M, Reed EF, Valenzuela NM, Wiebe C, Dijke IE, Sullivan HC, Nickerson P. (2020) Sensitization in Transplantation: Assessment of Risk (STAR) 2019 Working Group Meeting Report. Am J Transplant20(10):2652-2668
  • Tambur AR, Schinstock C, Maguire C, Lowe D, Smith B, Stegall M. (2020). Estimating alloantibody levels in highly sensitized renal allograft candidates: Using serial dilutions to demonstrate a treatment effect in clinical trials. Am J Transplant. 21(3):1278-1284
  • Senev A, Coemans M, Lerut E, Van Sandt V, Kerkhofs J, Daniëls L, Vanden Driessche L, Compernolle V,  Sprangers B, Van Loon E, Callemeyn J, Claas F, Tambur AR, Verbeke G, Kuypers D, Emonds M-P, Naesens M. (2020) The impact of eplet mismatch load on de novo occurrence of donor-specific anti-HLA antibodies, rejection, and graft failure after kidney transplantation: an observational cohort study. J Am Soc Nephrol. 31(9):2193-2204
  • Garcia-Sanchez C, Usenko CY, Herrera ND, Tambur AR. (2020) The shared epitope phenomenon – a potential impediment to virtual crossmatch accuracy. Clinical Transplantation 34(8):e13906.
  • Schinstock CA, Mannon RB, Budde K, Chong AS, Haas M, Knechtle S, Lefaucheur C,  Montgomery RA, Nickerson P, Tullius SG, Ahn C, Askar M, Crespo M, Chadban SJ, Feng S, Jordan SC, Man K, Mengel M, Morris RE, O’Doherty I, Ozdemir BH, Seron D, Tambur AR, Tanabe K, Taupin J, O’Connell PJ. (2020). Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: The 2019 Expert Consensus From the Transplantion Society Working Group. Transplantation 104(5):911-922.
  • Pinelli DF, Tambur AR. (2020). Virtual crossmatching for deceased donor transplantation: one size does not fit all. Kidney Int 97:659-662
  • Kaur N, Pinelli D, Kransdorf EP, Pando MJ, Smith G, Murphey CL, Kamoun M, Bray RA, Tambur A, Gragert L (2020) A blueprint for electronic utilization of ambiguous molecular HLA typing data in organ allocation systems and virtual crossmatch. Human Immunology 81:65-72
  • Manski CF, Tambur AR, Gmeiner M (2019) Predicting kidney transplant outcomes with partial knowledge of HLA mismatch. PNAS 116(41):20339-20345
  • Pinelli DF, Zachary AA, Friedewald JJ, Gjertson DW, Evans MA, Chatroop EN, Leffell MS, Vo AA, Jordan SC, Montgomery RA, Tambur AR (2019) Prognostic tools to assess candidacy for and efficacy of antibody-removal therapy. Am J Transplant 19:381-390
  • Tambur AR, McDowell H, Hod-Dvorai R, Abundis MAC, Pinelli DF (2019) The quest to decipher HLA immunogenicity: Telling friend from foe. Am J Transplant 19:2910-2925
  • Schinstock CA, Mannon RB, Budde K, Chong AS, Haas M, Knechtle S, Lefaucheur C, Montgomery RA,  Nickerson P, Tullius SG, Ahn C, Askar M, Crespo M, Chadban SG, Feng S, Jordan SC, Man K, Mengel M, Morris RE, O’Doherty I, Ozdemir BH, Seron D, Tambur AR, Tanabe K, Taupin J-L, O’Connell PJ (2019) Recommended treatment for antibody mediated rejection after kidney transplantation: the 2019 expert consensus from The Transplant Society working group. Transplantation
  • Tambur AR (2018) HLA Epitope Matching or Eplet Risk Stratification – the Devil is in the Details. Frontiers in Immunology 9:2010
  • Tambur AR (2018) Human Leukocyte Antigen matching in organ transplantation: what we know and how can we make it better (Revisiting the past, improving the future). Curr Opin Organ Transplant 23:470-476
  • Wiebe C, Tambur A, Nickerson PW (2018) A Call for Action – The transplant recipient’s expectation of precision in transplant medicine. Am J Transplant 18:2845-2846
  • Tambur AR, Camplbell P, Class FH……. Nickerson P (2018) Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report. Am J Transplant  18:1604-1614.
  • Leventhal JR, Miller J, Mathew JM, Kurian S, Tambur AR, Friedewald J, Charrette J, Abecassis MM (2018) Updated follow up of a tolerance protocol in HLA identical renal transplant pairs given donor hematopoietic stem cells. Human Immunol 79:277-282.
  • Tambur AR, Wiebe C (2018) HLA diagnostics: evaluating DSA strength by titration. Transplantation 102 S23-30.
  • Loupy A, Haas M, Solez K, Racusen L, Glotz D, Seron D….. Tambur AR, Zeevi A, Mengel M (2017) The Banff 2015 kidney meeting report: current challenges in rejection classification and prospects for adopting molecular pathology. Am J Transplant 17:28-41.
  • Tambur AR, Audry B, Antoine C, Suberbielle C, Glotz D, Jacquelinet C (2017) Harnessing Scientific and Technological Advances to Improve Equity in Kidney Allocation Policies. Am J Transplant 17:3149-3158
  • Pinelli DF, Fridewald JJ, Haarberg KMK, Radhakrishnan SL, Zitzner JR, Hanshew WE, Tambur AR (2017) Assessing the potential of angiotensin II type 1 receptor and donor specific anti-endothelial cell antibodies to predict long term kidney graft outcome. Human Immunol 78:421-427.
  • Hod Dvorai R, Pinelli DF, Tambur, AR. (2016) HLA Epitopes – Are We Ready for Clinical Prime Time? Historic Perspective and Future Needs. Clinical Transplantation 32:63-71
  • Levitsky J, Kaneku H, Jie C, Walsh RC, Abecassis M, Tambur AR (2016) Donor-Specific HLA Antibodies in Living Versus Deceased Donor Liver Transplant Recipients. Am J Transplant 16 2437–2444
  • Tambur AR (2016) HLA-DQ antibodies: are they real? Are they relevant? Why so many? Curr Opinn Organ Transplant 21(4):441-6
  • Tambur AR (2016) Auto and allo epitopes in DQ alloreactivity. Curr Opin Organ Transplant 21(4):355-61
  • Tambur AR (2016) Hiding in plain Sight – or a new look at HLA epitopes. A personal viewpoint. Am J Transplant 16:3286-3291
  • Tambur AR, Glotz D, Herrera ND, Chatroop EN, Roitberg T, Friedewald JJ, Gjersten D (2016) Can solid phase assays be better utilized to measure efficacy of antibody removal therapies? Human Immunology  77(8):624-30
  • Tambur AR & Lavee J (2016) Incorporating HLA antibodies results into clinical practice. Perspective J Heart Lung Transplant 35(7):851-6
  • Fernandez R, Chiu S, Raparia K, Garcha P, Farver C, Budev M, Tambur AR, DeCamp MM, Budinger S, Perlman H, Mohanakumar T, and Bharat A (2016) Humoral Human Lung Allograft Rejection by Tissue Restricted non-HLA antibodies. Ann Thorac Surg 102:339-341
  • Leventhal JR, Mathew J, Salomon DR, Kurian SM, Friedewald JJ, Gallon L, Konieczna I, Tambur AR, Charette J, Levitsky J, Jie C, Kanwar YS, Abecassis MM, Miller J (2016) Non-Chimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers Am J Transplant 16:221-234
  • Cusick MF & Tambur AR (2015) Advancing histocompatibility testing for solid organ transplantation – what is needed? A personal opinion. Clinical Transplants  31:193-201
  • Duquesnoy RJ, Gebel HM, Woodle ES, Nickerson P, Baxter-Lowe LA, Bray RA, Claas FH, Eckels DD, Friedewald JJ, Fuggle SV, Gerlach JA, Fung JJ, Kamoun M, Middleton D, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A (2015) High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms. Am J Transplant 15(10):2780-1
  • Tambur AR, Haarberg KMK, Freidewald JJ, Leventhal JR, Cusick MF, Jaramillo A, Abecassis MM, Kaplan B (2015) Unintended consequences of the new national kidney allocation policy in the US. Am J Transplant. 15(9):2465-9
  • Tambur AR, Herrera ND, Haareberg KMK, Cusick MF, Gordon RA, Leventhal JR, Friedewald JJ, Glotz D (2015) Assessing antibody strength: comparison of MFI, C1q, and Titer information. Am J Transplant 15(9):2421-30
  • Glotz D, Tambur A (2015) Stratifying Patients Based on Epitope Mismatching: Ready for Primetime? Am J Transplant. 15(8):2021-2
  • Frankfurt O, Zitzner J, Tambur AR. (2015) Real-time qPCR for chimerism assessment in allogeneic hematopoietic stem cell transplants from unrelated adult and double umbilical cord blood. Human Immunology 76:155-160
  • Duquesnoy RJ, Kamoun M, Baxter-Lowe LA, Woodle ES, Bray RA, Claas FHJ, Eckels DD, Friedewald JJ, Fuggle SV, Gebel HM, Gerlach JA, Fung JJ, Middleton D, Nickerson O, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A (2015) Personal Viewpoint: Should HLA Mismatch Acceptability for Sensitized Transplant Candidates Be Determined at the High-Resolution rather than the Antigen Level? Am J Transplant 15:923-930
  • Tambur AR and Claas FH (2015) HLA epitopes as viewed by antibodies: what is it all about? Am J Transplant 15:1148-1154