Charnaya O, Ishaque T, Hallett A, Kimball P, Morris GP, Coppage M, Schmitz JL, Timofeeva O, Lázár-Molnár E, Zhang A, Krummey S, Hidalgo L, Segev MD DL, Tambur AR., Massie AB. The Impact of HLA-DQαβ Heterodimer Mismatch on Living Donor Kidney Allograft Outcomes. Transplantation 2024, Sept 5, PMID: 39233325 doi: 10.1097/TP.0000000000005198.
Torija A, Matignon M, Vincenti F, Casanova-Ferrer F, Pilon C, Tambur AR, Donadeu L, Crespo E, Kervella D, Meneghini M, Torres IB, Hafkamp F, Martinez-Lacalle A, Carrera C, Zúñiga J, Brar A, Cruzado J, Gaber AO, Lee H, Montgomery RA,…Bestard O. Anti-HLA serological response to CD38-targeting desensitization therapy is challenged by peripheral memory B-cells in highly sensitized kidney transplant candidates. AJT 2024, Aug 10:S1600 PMID 3913412 doi: 10.1016/j/ajt.2024.08.004
Tambur AR. Commentary on Review: Forming New Perspective Approaches to Determination of Donor Compatibility. International Journal of Immunogenetics 2024 Aug:51(4):252-253 PMID:38794787 https://doi.org/10.1111/iji.12680
Debyser T, Wellekens K, Senev A, Coemans M, Koshy P, Van Loon E, Callemeyn J, Kuyper D, Tambur AR, Emonds M-P, Naesens M. Sensitive HLA antibody testing and the risk of antibody-mediated rejection and graft failure: Value of sensitive HLA antibody testing. HLA 2024, Jun:103(6):e15586 PMID 38932739 doi: 10.1111.tan.15586
Senev A, Tambur AR, Kosmoliaptsis V, Copley HC, Garcia-Zanchez C, Usenko C, Ildstad S, Leventhal JR. HLA molecular mismatches and induced donor-specific tolerance in combined living donor kidney and hematopoietic stem cell transplantation. Frontiers in Immunology 2024 Mar 27:15:1377535 PMID: 38601147 doi: 10.3389/fimmu.2024.1377535
Meneghini M, Tambur AR. HLA (emphasis of DQ) compatibility for longer allograft survival in pediatric transplantation: modern evidence and challenges. Pediatric transplantation 2024 Feb:28(1):e14606 https://doi.org/10.1111/petr.14606
Vincenti F, Bestard O, Brar A, Cruzado JM, Seron D, Gaber AO, Ali N, Tambur AR, Lee H, Abbadessa G, Paul J-A, Dudek M, Siegel RJ, Torija A, Semiond D, Lépine L, Ternes N, Montgomery RA, Stegall M. Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant. JASN 2024; 35(3) 347-360. PMID: 38147137 doi: 10.1681/ASN.0000000000000287
Margeta D, Noguchi H, Khazaie S, Herlitz LC, Augustine JJ, Heeger PS, Tambur AR, Fairchild RL, Baldwin WM III. Compartmentalization of transcripts during antibody mediated rejection in renal transplants BioRxiv doi: https://doi.org/10.1101/2024.05.20.594331
Maguire C, Crivello P, Fleischhauer K, Isaacson D, Casillas A, Kramer CSM, Copley HC, Heidt S, Kosmoliaptsis V, Meneghini M, Gmeiner M, Schold J, Louzoun Y, Tambur AR. Qualitative, rather than quantitative, differences between HLA-DQ alleles affect HLA-DQ immunogenicity in organ transplantation. HLA: Immune Response Genetics 2024 Apr;103(4)e15455 doi:10.1111/tan.15455
Meneghini M, Tambur AR. HLA-DQ antibodies in alloimmunity, what makes them different? Curr Opin Organ Transplant 2023, ePub PMID 37219535
Tambur, AR. My life in HLA. ASHI quarterly, 2023 January issue
Lefaucheur C, Louis K, Morris AB, Taupin JL, Nickerson P, Tambur AR, Gebel HM, Reed EF; STAR 2022 Working Group. Clinical recommendations for posttransplant assessment of anti-HLA (Human Leukocyte Antigen) donor-specific antibodies: A Sensitization in Transplantation: Assessment of Risk consensus document. AJT 2023 23(1):115-132. PMID 36695614
Tambur AR, et al Sensitization in Transplantation: Assessment of Risk 2022 Working Group Meeting Report. AJT 2023; 23(1):133-149 PMID 36695615
Tambur AR, Audry B, Glotz D, Jacquelinet C. Improving equity in kidney transplant allocation policies through a novel genetic metric: the matched donor potential. AJT 2023; 23(1):45-54 PMID 36695620
Kobashigawa J, Hall S, Shah P, Fine B, Halloran P, Jackson AM, Khush KK, Margulies KB, Sani MM, Patel JK, Patel N, Petster E: conference participants. AJT 2023 Jun:23(6):727-735 PMID: 36870390 doi: 10.1016/j.ajt.2023.02.025
Naesens M, Roufosse C, Colvin RC, Haas M, ……, Tambur AR, …. Loupy A, Mengel M. The Banff 2022 Kidney Meeting Report: Re-Appraisal of Microvascular Inflammation and the Role of Biopsy-Based Transcript Diagnostics. AJT 2023: Oct 27:s1600 PMID 39491095 doi: 10.1016/j.ajt.2023.10.016.
Hod-Dvorai R, Lee R, Muluhngwi P, Raijmakers M, Shetty A, Tambur AR, Ison MG. Development of De Novo Donor Specific Antibodies in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction. Transpl Infect Dis. 2022 Nov 22:e13993. doi: 10.1111/tid.13993. Online ahead of print.PMID: 36413505
Isaacson D, Schold JD, Gmeiner MW, Copley HC, Kosmoliaptsis V, Tambur AR. HLA-DQ mismatches lead to more unacceptable antigens, greater sensitization, and increased disparities as demonstrated in repeat transplant candidates. J Am Soc Nephrol. 2022 Dec;33(12):2293-2305. doi: 10.1681/ASN.2022030296. Epub 2022 Aug 31.PMID: 36450598
Tambur AR, Das R. Can we use eplets (or molecular) mismatch load analysis to improve organ allocation: The hope and the hype. 2023 1:107(3):605-615. PMID: 36163639
Maguire C, Tambur AR. Potential implication of HLA-DQ heterodimer high-resolution typing on kidney transplant outcomes and equity. Current Transplant Reports 2023 DOI: 10.1007/s40472-023-00407-3
Tambur AR, Schinstock C. Clinical Utility of Serial Serum Dilutions for HLA antibody Interpretation. HLA in press
Garcia-Sanchez C, Castillas-Abundis MA, Pinelli DF, Tambur AR, Hod-Dvorai R, Impact of SIRPα Polymorphism on Transplant Outcomes in HLA-identical Living Donor Kidney Transplantation. Clinical Transplantation.in press doi: 10.1111/ctr.14406. Online ahead of print.PMID: 34180101
Rachel M Engen, Anat R Tambur. Accurate eplet identification is necessary for accurate risk assessment. AJT 2021 21(10): 3540org/10.1111/ajt.16612 PMID: 33866684
Schinstock CA, Stegall MD, Tambur AR. Current Approaches to Desensitization in Solid Organ Transplantation. Frontiers in Immunology, section Alloimmunity and Transplantation. 2021 11;12:686271 doi: 10.3389/fimmu.2021.686271 PMID: 34046044
Asano Y, Daccache J, Jain D, Ko K, Kinloch A, Veselits M, Wolfgeher D, Chang A, Josephson M, Cunningham P, Tambur A, Khan AA, Pillai S, Chong AS, Clark MR. Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection. Nature communications 2021, 12:4372
Engen RM, Jedraszko AM, Conciatori MA, Tambur AR. (2021) Substituting imputation of HLA antigens for high resolution HLA typing: Evaluation of a multiethnic population and implications for molecular mismatch evaluation for clinical decision making. Am J Transplant. 21(1):344-352.
Dong R, Shetty A, Tambur AR, Ison MG. Outcomes of Repeat Kidney Transplantation Following Prior Graft Failure Due to BK Nephropathy: A Single Center Retrospective Study” in its current form for publication in Transplant Infectious Disease. Transplant Infectious Disease 2021 23(4):e13672 PMID: 34153164 DOI: 10.1111/tid.13672
Mathew J, Kurian S, Cravedi P, Tambur A, Kexin G, Zhao L, Levitsky J: Immune and Gene Expression Profiling During Tacrolimus to Everolimus Conversion Early After Liver Transplantation. Hum Immunol 2021 82(2): 81-88 doi: 10.1016/j.humimm.2020.10.012. PMID: 33213941
Maguire CH, Schinstock CA, Tambur AR. (2020). Measuring human leukocyte antigen alloantibodies: beyond a binary decision. Curr Opin Organ Transplant. 25(6):529-535
Tambur AR, Campbell P, Chong AS, Feng S, Ford ML, Gebel H, Gill RG, Kelsoe G, Kosmoliaptsis V, Mannon RB, Mengel M, Reed EF, Valenzuela NM, Wiebe C, Dijke IE, Sullivan HC, Nickerson P. (2020) Sensitization in Transplantation: Assessment of Risk (STAR) 2019 Working Group Meeting Report. Am J Transplant. 20(10):2652-2668
Tambur AR, Schinstock C, Maguire C, Lowe D, Smith B, Stegall M. (2020). Estimating alloantibody levels in highly sensitized renal allograft candidates: Using serial dilutions to demonstrate a treatment effect in clinical trials. Am J Transplant. 21(3):1278-1284
Senev A, Coemans M, Lerut E, Van Sandt V, Kerkhofs J, Daniëls L, Vanden Driessche L, Compernolle V, Sprangers B, Van Loon E, Callemeyn J, Claas F, Tambur AR, Verbeke G, Kuypers D, Emonds M-P, Naesens M. (2020) The impact of eplet mismatch load on de novo occurrence of donor-specific anti-HLA antibodies, rejection, and graft failure after kidney transplantation: an observational cohort study. J Am Soc Nephrol. 31(9):2193-2204
Garcia-Sanchez C, Usenko CY, Herrera ND, Tambur AR. (2020) The shared epitope phenomenon – a potential impediment to virtual crossmatch accuracy. Clinical Transplantation 34(8):e13906.
Schinstock CA, Mannon RB, Budde K, Chong AS, Haas M, Knechtle S, Lefaucheur C, Montgomery RA, Nickerson P, Tullius SG, Ahn C, Askar M, Crespo M, Chadban SJ, Feng S, Jordan SC, Man K, Mengel M, Morris RE, O’Doherty I, Ozdemir BH, Seron D, Tambur AR, Tanabe K, Taupin J, O’Connell PJ. (2020). Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: The 2019 Expert Consensus From the Transplantion Society Working Group. Transplantation 104(5):911-922.
Pinelli DF, Tambur AR. (2020). Virtual crossmatching for deceased donor transplantation: one size does not fit all. Kidney Int 97:659-662
Kaur N, Pinelli D, Kransdorf EP, Pando MJ, Smith G, Murphey CL, Kamoun M, Bray RA, Tambur A, Gragert L (2020) A blueprint for electronic utilization of ambiguous molecular HLA typing data in organ allocation systems and virtual crossmatch. Human Immunology 81:65-72
Maguire AH, Schinstock CA, Tambur AR. Measuring HLA alloantibodies – beyond a binary decision. Current Opinion in Organ Transplantation 2020, 25:529-535.
Manski CF, Tambur AR, Gmeiner M (2019) Predicting kidney transplant outcomes with partial knowledge of HLA mismatch. PNAS 116(41):20339-20345
Pinelli DF, Zachary AA, Friedewald JJ, Gjertson DW, Evans MA, Chatroop EN, Leffell MS, Vo AA, Jordan SC, Montgomery RA, Tambur AR (2019) Prognostic tools to assess candidacy for and efficacy of antibody-removal therapy. Am J Transplant 19:381-390
Tambur AR, McDowell H, Hod-Dvorai R, Abundis MAC, Pinelli DF (2019) The quest to decipher HLA immunogenicity: Telling friend from foe. Am J Transplant 19:2910-2925
Schinstock CA, Mannon RB, Budde K, Chong AS, Haas M, Knechtle S, Lefaucheur C, Montgomery RA, Nickerson P, Tullius SG, Ahn C, Askar M, Crespo M, Chadban SG, Feng S, Jordan SC, Man K, Mengel M, Morris RE, O’Doherty I, Ozdemir BH, Seron D, Tambur AR, Tanabe K, Taupin J-L, O’Connell PJ (2019) Recommended treatment for antibody mediated rejection after kidney transplantation: the 2019 expert consensus from The Transplant Society working group. Transplantation
Schold J, Tambur AR, Mohan S, Kaplan B. Calibration of Priority Points for Sensitization Status of Kidney Transplant Candidates in the United States. CJASN 2024 June 1:19(6):767-777. doi: 10.2215/CJN.0000000000000449
Tambur AR (2018) HLA Epitope Matching or Eplet Risk Stratification – the Devil is in the Details. Frontiers in Immunology 9:2010
Tambur AR (2018) Human Leukocyte Antigen matching in organ transplantation: what we know and how can we make it better (Revisiting the past, improving the future). Curr Opin Organ Transplant 23:470-476
Wiebe C, Tambur A, Nickerson PW (2018) A Call for Action – The transplant recipient’s expectation of precision in transplant medicine. Am J Transplant 18:2845-2846
Tambur AR, Camplbell P, Class FH……. Nickerson P (2018) Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report. Am J Transplant 18:1604-1614.
Leventhal JR, Miller J, Mathew JM, Kurian S, Tambur AR, Friedewald J, Charrette J, Abecassis MM (2018) Updated follow up of a tolerance protocol in HLA identical renal transplant pairs given donor hematopoietic stem cells. Human Immunol 79:277-282.
Tambur AR, Wiebe C (2018) HLA diagnostics: evaluating DSA strength by titration. Transplantation 102 S23-30.
Loupy A, Haas M, Solez K, Racusen L, Glotz D, Seron D….. Tambur AR, Zeevi A, Mengel M (2017) The Banff 2015 kidney meeting report: current challenges in rejection classification and prospects for adopting molecular pathology. Am J Transplant 17:28-41.
Tambur AR, Audry B, Antoine C, Suberbielle C, Glotz D, Jacquelinet C (2017) Harnessing Scientific and Technological Advances to Improve Equity in Kidney Allocation Policies. Am J Transplant 17:3149-3158
Pinelli DF, Fridewald JJ, Haarberg KMK, Radhakrishnan SL, Zitzner JR, Hanshew WE, Tambur AR (2017) Assessing the potential of angiotensin II type 1 receptor and donor specific anti-endothelial cell antibodies to predict long term kidney graft outcome. Human Immunol 78:421-427.
Hod Dvorai R, Pinelli DF, Tambur, AR. (2016) HLA Epitopes – Are We Ready for Clinical Prime Time? Historic Perspective and Future Needs. Clinical Transplantation 32:63-71
Levitsky J, Kaneku H, Jie C, Walsh RC, Abecassis M, Tambur AR (2016) Donor-Specific HLA Antibodies in Living Versus Deceased Donor Liver Transplant Recipients. Am J Transplant 16 2437–2444
Tambur AR (2016) HLA-DQ antibodies: are they real? Are they relevant? Why so many? Curr Opinn Organ Transplant 21(4):441-6
Tambur AR (2016) Hiding in plain Sight – or a new look at HLA epitopes. A personal viewpoint. Am J Transplant 16:3286-3291
Tambur AR, Glotz D, Herrera ND, Chatroop EN, Roitberg T, Friedewald JJ, Gjersten D (2016) Can solid phase assays be better utilized to measure efficacy of antibody removal therapies? Human Immunology 77(8):624-30
Tambur AR & Lavee J (2016) Incorporating HLA antibodies results into clinical practice. Perspective J Heart Lung Transplant 35(7):851-6
Fernandez R, Chiu S, Raparia K, Garcha P, Farver C, Budev M, Tambur AR, DeCamp MM, Budinger S, Perlman H, Mohanakumar T, and Bharat A (2016) Humoral Human Lung Allograft Rejection by Tissue Restricted non-HLA antibodies. Ann Thorac Surg 102:339-341
Leventhal JR, Mathew J, Salomon DR, Kurian SM, Friedewald JJ, Gallon L, Konieczna I, Tambur AR, Charette J, Levitsky J, Jie C, Kanwar YS, Abecassis MM, Miller J (2016) Non-Chimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers Am J Transplant 16:221-234
Cusick MF & Tambur AR (2015) Advancing histocompatibility testing for solid organ transplantation – what is needed? A personal opinion. Clinical Transplants 31:193-201
Duquesnoy RJ, Gebel HM, Woodle ES, Nickerson P, Baxter-Lowe LA, Bray RA, Claas FH, Eckels DD, Friedewald JJ, Fuggle SV, Gerlach JA, Fung JJ, Kamoun M, Middleton D, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A (2015) High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms. Am J Transplant 15(10):2780-1
Tambur AR, Haarberg KMK, Freidewald JJ, Leventhal JR, Cusick MF, Jaramillo A, Abecassis MM, Kaplan B (2015) Unintended consequences of the new national kidney allocation policy in the US. Am J Transplant. 15(9):2465-9
Tambur AR, Herrera ND, Haareberg KMK, Cusick MF, Gordon RA, Leventhal JR, Friedewald JJ, Glotz D (2015) Assessing antibody strength: comparison of MFI, C1q, and Titer information. Am J Transplant 15(9):2421-30
Glotz D, Tambur A (2015) Stratifying Patients Based on Epitope Mismatching: Ready for Primetime? Am J Transplant. 15(8):2021-2
Frankfurt O, Zitzner J, Tambur AR. (2015) Real-time qPCR for chimerism assessment in allogeneic hematopoietic stem cell transplants from unrelated adult and double umbilical cord blood. Human Immunology76:155-160
Duquesnoy RJ, Kamoun M, Baxter-Lowe LA, Woodle ES, Bray RA, Claas FHJ, Eckels DD, Friedewald JJ, Fuggle SV, Gebel HM, Gerlach JA, Fung JJ, Middleton D, Nickerson O, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A (2015) Personal Viewpoint: Should HLA Mismatch Acceptability for Sensitized Transplant Candidates Be Determined at the High-Resolution rather than the Antigen Level? Am J Transplant15:923-930
Tambur AR and Claas FH (2015) HLA epitopes as viewed by antibodies: what is it all about? Am J Transplant15:1148-1154
