Publications

Wisniewski BT and Lackner LL. (2024) Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA. bioRxiv DOI: 10.1101/2024.07.18.604121

Casler JC, Harper CS, White AJ, Anderson HL, and Lackner LL. (2024) Mitochondria-ER-PM contacts regulate PI(4)P distribution and mitochondrial division. Journal of Cell Biology. DOI: 10.1083/jcb.202308144

Harper CS, Casler JC, and Lackner LL. (2023) Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering. MBoC DOI: 10.1091/mbc.E23-05-0168

White AJ, Harper CS, Rosario EM, Dietz JV, Addis HG, Fox JL, Khalimonchuk O, and Lackner LL. (2022) Loss of Num1-mediated cortical dynein anchoring negatively impacts respiratory growth. Journal of Cell Science. DOI: 10.1242/jcs.259980

Anderson HL, Casler JC, and Lackner LL. (2022) Hierarchical integration of mitochondrial and nuclear positioning pathways by the Num1 EF hand. MBoC. DOI: 10.1091/mbc.E21-12-0610-T

Casler JC and Lackner LL. (2021) Cnm1: A bridge between mitochondria and nuclear ER. JCB. DOI: 10.1083/jcb.202109021

Gibson SB, Harper CS, Lackner LL, and Andersen EC. (2021) The Caenorhabditis elegans and Haemonchus contortus beta-tubulin genes cannot substitute for loss of the Saccharomyces cerevisiae beta-tubulin gene. MicroPubl Biol. DOI: 10.17912/micropub.biology.000411

Hoppins S, Lackner LL, Lee JE, Mears JA. (2020) Chapter 20 – In vitro and in vivo assays for mitochondrial fission and fusion. Method Cell Biol. DOI: 10.1016/bs.mcb.2019.11.010

Harper CS*, White AJ*, and Lackner LL. (2020) The multifunctional nature of mitochondria contact site proteins. Curr Opin Cell Biol DOI: 10.1016/j.ceb.2020.02.010 *co-first authors, listed in alphabetical order

Abrisch RG, Gumbin SC, Wisniewski BT, Lackner LL, and Voeltz GK. (2020) Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology. JCB. DOI: 10.1083/jcb.201911122.

Lackner LL. (2019) The Expanding and Unexpected Functions of Mitochondria Contact Sites. Trends Cell Biol. DOI: 10.1016/j.tcb.2019.02.009.

Kraft LM and Lackner LL. (2019) A conserved mechanism for mitochondria-dependent dynein anchoring. MBoC. DOI: 10.1091/mbc.E18-07-0466.

Chen W, Ping HA, Lackner LL. (2018) Direct membrane binding and self-interaction contribute to Mmr1 function in mitochondrial inheritance. MBoC. DOI: 10.1091/mbc.E18-02-0122.

Schmit HL, Kraft LM, Lee-Smith CF, Lackner LL. (2018) The role of mitochondria in anchoring dynein to the cell cortex extends beyond clustering the anchor protein. Cell Cycle. DOI: 10.1080/15384101.2018.1480226.

Kraft LM and Lackner LL. (2017) Mitochondrial-driven assembly of a cortical anchor for mitochondria and dynein. JCB. DOI: 10.1083/jcb.201702022.

Kraft LM and Lackner LL. (2017) Mitochondrial anchors: Positioning mitochondria and more. Biochem Biophys Res Commun. DOI: 10.1016/j.bbrc.2017.06.193.

Ping HA, Kraft LM, Chen W, Nilles AE, Lackner LL. (2016) Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities. JCB. DOI: 10.1083/jcb.201511021.

Lackner LL. (2014) Shaping the dynamic mitochondrial network. BMC Biol. DOI: 10.1186/1741-7007-12-35.

Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. (2013) ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. eLife. DOI: 10.7554/eLife.00422.

Lackner LL. (2013) Determining the shape and cellular distribution of mitochondria: the integration of multiple activities. Curr Opin Cell Biol. DOI: 10.1016/j.ceb.2013.

Lackner LL, Graef M, Murley A, Ping H and Nunnari J. (2013) Endoplasmic reticulum associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria. PNAS. DOI: 10.1073/pnas.1215232110.

Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, DeVay RM, Lackner LL, Schuldiner M, Westermann B, Weissman JS, and Nunnari J. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Journal of Cell Biology. DOI: 10.1083/jcb.201107053.

Friedman JR, Lackner LL, West M, DiBenedetto JR, Nunnari J, Voeltz GK. (2011) ­ER tubules mark sites of mitochondrial division. Science. DOI: 10.1126/science.1207385.

Mears JA, Lackner LL, Fang S, Ingerman E, Nunnari J, Hinshaw JE. (2011) Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission. Nature Structural Molecular Biology. DOI: 10.1038/nsmb.1949.

Lackner LL, Nunnari J. (2010) Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine. Chemistry and Biology. DOI: 10.1016/j.chembiol.2010.05.016.

DeVay RM, Dominguez-Ramirez L, Lackner LL, Hoppins S, Stahlberg H, Nunnari J. (2009) The roles of mitochondrial inner membrane dynamin isoforms in fusion. Journal of Cell Biology. DOI: 10.1083/jcb.200906098.

Lackner LL, Horner JS, Nunnari J. (2009) Mechanistic Analysis of a Dynamin Effector. Science. DOI: 10.1126/science.1176921.

Lackner LL, Nunnari J. (2009) The Molecular Mechanism and Cellular Functions of Mitochondrial Division. Biochimica et Biophysica Acta. DOI: 10.1016/j.bbadis.2008.11.011.

Lackner LL, Hoppins S, Nunnari J. (2007) The machines that divide and fuse mitochondria. Annual Review of Biochemistry. DOI: 10.1146/annurev.biochem.76.071905.090048.