Research Overview
Our research program studies mechanisms that govern cell fate specification, stem cell maintenance, aging, cancer and human skin diseases. We use single-cell genomics and computational tools, live animal imaging and genetically engineered mouse models to study gene expression regulation mediated by transcription factors, epigenetic regulators, miRNAs and RNA binding proteins as well as metabolic genes at the single-cell resolution.
Research Areas
Maintenance and aging of skin stem cells
Single cell genomic analyses of gene regulatory network
Imaging of molecular and cellular events in live animals
