Yap Laboratory

The Yap Lab is part of the Department of Microbiology-Immunology at Northwestern University Feinberg School of Medicine in Chicago. The lab is located in the Streeterville neighborhood of Chicago along the shores of beautiful Lake Michigan. We are a bacteriology lab broadly interested in understanding the role of accessory factors, antibiotics, and rRNA-modifying enzymes in regulating the efficiency and fidelity of mRNA translation. We use a multi-disciplinary approach that spans genetics, structural biology, omics technologies, biochemistry, and whole animal infection studies to investigate how these factors and small molecules affect ribosome function in methicilin-resistant Staphylococcus aureus (MRSA).

Our group members hail from different countries (1, 2, 3, 4, 5, 6, 7, 8), bringing distinct perspectives, life experiences, and identities. We are committed to maintaining a safe and collaborative lab environment that celebrates open-mindedness, kindness, and curiosity in all its forms.