Our Mission
The Yvette Wong lab aims to:
- Use super-resolution live cell microscopy to uncover new cellular pathways
- Explore novel roles and regulation of inter-organelle contact sites in health and disease
- Investigate how mitochondria-lysosome contacts drive cellular &neuronal homeostasis and human disease
- Elucidate new mechanisms resulting in neurodegeneration in Parkinson’s, Charcot-Marie-Tooth, Alzheimer’s disease, ALS and Frontotemporal dementia.
Mitochondria-Lysosome Contacts
Mitochondria-lysosome contact sites allow for bidirectional crosstalk between both organelles
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Mitochondria-Lysosome Contacts
~~ We are investigating new regulators and functions of mitochondria-lysosome contact sites ~~
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Neurodegenerative Disease Mechanisms
Defects in organelle dynamics may contribute to multiple neurological diseases
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Neurodegenerative Disease Mechanisms
~~ We are discovering new pathways that contribute to the pathogenesis of neurodegenerative diseases ~~
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Join Our Lab
We welcome new members (PhD students, postdoctoral fellows & research technicians) who are interested in neurodegenerative diseases, organelle dynamics and live cell microscopy.
Our lab is located in beautiful downtown Chicago at Northwestern University’s Feinberg School of Medicine (Department of Neurology).
Read Our Publications
Read more about our published work identifying new organelle dynamics, mitochondria-lysosome contact sites, and pathways involved in neurodegeneration.
