Our Mission
The Yvette Wong lab aims to:
- Use super-resolution live cell microscopy to uncover new cellular pathways
- Explore novel roles and regulation of inter-organelle contact sites in health and disease
- Investigate how mitochondria-lysosome contacts drive cellular &neuronal homeostasis and human disease
- Elucidate new mechanisms resulting in neurodegeneration in Parkinson’s, Charcot-Marie-Tooth, Alzheimer’s disease, ALS and Frontotemporal dementia.

Mitochondria-Lysosome Contacts
Mitochondria-lysosome contact sites allow for bidirectional crosstalk between both organelles
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Mitochondria-Lysosome Contacts
~~ We are investigating new regulators and functions of mitochondria-lysosome contact sites ~~
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Neurodegenerative Disease Mechanisms
Defects in organelle dynamics may contribute to multiple neurological diseases
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Neurodegenerative Disease Mechanisms
~~ We are discovering new pathways that contribute to the pathogenesis of neurodegenerative diseases ~~
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Read Our Publications
Read more about our published work identifying new organelle dynamics, mitochondria-lysosome contact sites, and pathways involved in neurodegeneration.
Join Our Lab
Contact us if you are passionate about neurodegenerative diseases, organelle dynamics and live cell microscopy, and are interested in a position in our lab (PhD students, Postdoctoral Fellows & Research Technicians).
Our lab is located in beautiful downtown Chicago at Northwestern University’s Feinberg School of Medicine (Department of Neurology).



