The Pollack Lab is a cancer immunology lab located on the downtown campus of Northwestern University’s Feinberg School of Medicine and Robert H. Lurie Comprehensive Cancer Center, in the heart of Chicago. Our lab is dedicated to curing sarcomas, cancers of the bone and soft tissue. Our ground-breaking work has led to important discoveries resulting in multiple clinical trials that are actively shaping the care of sarcoma patients all around the world. Furthermore, through the careful study of these unique cancers, we have uncovered fundamental insights that are shaping the development of immunotherapy for all cancers.
Our Mission
CAR-T Immunotherapy
Use genetically engineered T cells, CARs, as an immunotherapy for pet dogs bearing naturally occurring sarcomas to gain insights on how it can be translated into human patients.
Developing understanding of immune microenvironment of synovial and myxoid sarcomas
Conduct deep analysis of the immune microenvironment of synovial sarcoma and myxoid liposarcoma, two sarcoma subtypes that have very strong expression of highly immunogenic antigens but very cold microenvironments.
Understating the role of some key T cell receptors in T cell response
Characterize T Cell Receptor sequences that appear to have special importance in clinical settings.