Schwartz Lab Articles
2024
A presynaptic source drives differing levels of surround suppression in two mouse retinal ganglion cell types
Swygart D, Yu WQ, Takeuchi S, Wong ROL, Schwartz GW. A presynaptic source drives differing levels of surround suppression in two mouse retinal ganglion cell types. Nat Commun. 2024 Jan 18;15(1):599. doi: 10.1038/s41467-024-44851-w. PubMed PMID: 38238324; PubMed Central PMCID: PMC10796971.
2023
Putting early sensory neurons to sleep
Fadjukov J, Schwartz G. Putting early sensory neurons to sleep. Elife. 2023 Nov 10;12. doi: 10.7554/eLife.93339. PubMed PMID: 37947192; PubMed Central PMCID: PMC10637771.
Thrombospondin-1 proteomimetic polymers exhibit anti-angiogenic activity in a neovascular age-related macular degeneration mouse model.
Choi W, Nensel AK, Droho S, Fattah MA, Mokashi-Punekar S, Swygart DI, Burton ST, Schwartz GW, Lavine JA, Gianneschi NC. Thrombospondin-1 proteomimetic polymers exhibit anti-angiogenic activity in a neovascular age-related macular degeneration mouse model. Sci Adv. 2023 Oct 13;9(41):eadi8534. doi: 10.1126/sciadv.adi8534. Epub 2023 Oct 13. PubMed PMID: 37831763; PubMed Central PMCID: PMC10575579.
Optimal Burstiness in Populations of Spiking Neurons Facilitates Decoding of Decreases in Tonic Firing.
Durian SCL, Agrios M, Schwartz GW. Optimal Burstiness in Populations of Spiking Neurons Facilitates Decoding of Decreases in Tonic Firing. Neural Comput. 2023 Jun 20;:1-41. doi: 10.1162/neco_a_01595. [Epub ahead of print] PubMed PMID: 37432862.
IRIS: Integrated Retinal Functionality in Image Sensors.
Yin Z, Kaiser MA, Camara LO, Camarena M, Parsa M, Jacob A, Schwartz G, Jaiswal A. IRIS: Integrated Retinal Functionality in Image Sensors. Front Neurosci. 2023;17:1241691. doi: 10.3389/fnins.2023.1241691. eCollection 2023. PubMed PMID: 37719155; PubMed Central PMCID: PMC10502419.
2022
Unified Classification of Mouse Retinal Ganglion Cells Using Function, Morphology, and Gene Expression
Goetz, J., Jessen, Z. F., Jacobi, A., Mani, A., Cooler, S., Greer, D., … & Schwartz, G. W. (2022). Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression. Cell Reports, 40(2), 111040.
Differences In Spike Generation Instead Of Synaptic Inputs Determine The Feature Selectivity Of Two Retinal Cell Types
Wienbar, S., & Schwartz, G. W. (2022). Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types. Neuron.
Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells.
D’Souza SP, Swygart DI, Wienbar SR, Upton BA, Zhang KX, Mackin RD, Casasent AK, Samuel MA, Schwartz GW, Lang RA. Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells. J Comp Neurol. 2022 Jun;530(8):1247-1262. doi: 10.1002/cne.25272. Epub 2021 Dec 15. PubMed PMID: 34743323; PubMed Central PMCID: PMC8969148.
Gap junctions and connexin hemichannels both contribute to the electrical properties of retinal pigment epithelium
Predicting and Manipulating Cone Responses to Naturalistic Inputs
Angueyra JM, Baudin J, Schwartz GW, Rieke F. Predicting and Manipulating Cone Responses to Naturalistic Inputs. J Neurosci. 2022 Feb 16;42(7):1254-1274. doi: 10.1523/JNEUROSCI.0793-21.2021. Epub 2021 Dec 23. PubMed PMID: 34949692; PubMed Central PMCID: PMC8883858.
2021
Color Vision: More Than Meets The Eye
Schwartz, G. W. (2021). Color vision: More than meets the eye. Current Biology, 31(15), R948-R950.
Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.
Parmhans N, Fuller AD, Nguyen E, Chuang K, Swygart D, Wienbar SR, Lin T, Kozmik Z, Dong L, Schwartz GW, Badea TC. Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. J Comp Neurol. 2021 Jun;529(8):1926-1953. doi: 10.1002/cne.25065. Epub 2020 Nov 10. PubMed PMID: 33135183; PubMed Central PMCID: PMC8009822.
An Offset ON-OFF Receptive Field Is Created By Gap Junctions Between Distinct Types Of Retinal Ganglion Cells
Cooler, S. Schwartz, G. W. (2021). An offset ON–OFF receptive field is created by gap junctions between distinct types of retinal ganglion cells. Nature Neuroscience 24, 105–115.
2018
A Self-Regulating Gap Junction Network Of Amacrine Cells Controls Nitric Oxide Release In The Retina
Jacoby, J., Nath, A., Jessen, Z. F., & Schwartz, G. W. (2018). A self-regulating gap junction network of amacrine cells controls nitric oxide release in the retina. Neuron, 100(5), 1149-1162.
2017
Electrical Synapses Convey Orientation Selectivity In The Mouse Retina
Nath, A., & Schwartz, G. W. (2017). Electrical synapses convey orientation selectivity in the mouse retina. Nature communications, 8(1), 2025.
Circuit Mechanisms of a Retinal Ganglion Cell with Stimulus-Dependent Response Latency and Activation Beyond Its Dendrites
Mani, A., & Schwartz, G. W. (2017). Circuit mechanisms of a retinal ganglion cell with stimulus-dependent response latency and activation beyond its dendrites. Current Biology, 27(4), 471-482.
Three Small-Receptive-Field Ganglion Cells in the Mouse Retina Are Distinctly Tuned to Size, Speed, and Object Motion
Jacoby, J., & Schwartz, G. W. (2017). Three small-receptive-field ganglion cells in the mouse retina are distinctly tuned to size, speed, and object motion. Journal of Neuroscience, 37(3), 610-625.
Cardinal Orientation Selectivity Is Represented by Two Distinct Ganglion Cell Types in Mouse Retina
Nath, A., & Schwartz, G. W. (2016). Cardinal orientation selectivity is represented by two distinct ganglion cell types in mouse retina. Journal of Neuroscience, 36(11), 3208-3221.
An Amacrine Cell Circuit for Signaling Steady Illumination in the Retina
Jacoby, J., Zhu, Y., DeVries, S. H., & Schwartz, G. W. (2015). An amacrine cell circuit for signaling steady illumination in the retina. Cell reports, 13(12), 2663-2670.
Book
Retinal Computation
Schwartz GW. (2021). Retinal Computation. Elsevier.
Preprints
The Olivary Pretectal Nucleus Receives Visual Input of High Spatial Resolution
Levine JN, Schwartz GW (2020). The Olivary Pretectal Nucleus Receives Visual Input of High Spatial Resolution. bioRxiv:2020.06.23.168054.
Mind The Gap: Decoding Decreases In Tonic Firing In Populations Of Spiking Neurons
Durian, S., Agrios, M., & Schwartz, G. W. (2022). Mind the gap: decoding decreases in tonic firing in populations of spiking neurons. bioRxiv.
Collaborations
Retinal Patterns And The Cellular Repertoire Of Neuropsin (Opn5) Retinal Ganglion Cells
D’Souza, S. P., Swygart, D. I., Wienbar, S. R., Upton, B. A., Zhang, K. X., Mackin, R. D., … & Lang, R. A. (2022). Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells. Journal of Comparative Neurology, 530(8), 1247-1262.
Gap Junctions And Connexin Hemichannels Both Contribute To The Electrical Properties Of Retinal Pigment Epithelium
Fadjukov, J., Wienbar, S., Hakanen, S., Aho, V., Vihinen-Ranta, M., Ihalainen, T. O., … & Nymark, S. (2022). Gap junctions and connexin hemichannels both contribute to the electrical properties of retinal pigment epithelium. Journal of General Physiology, 154(4), e202112916.
Predicting and Manipulating Cone Responses to Naturalistic Inputs
Angueyra, J. M., Baudin, J., Schwartz, G. W., & Rieke, F. (2022). Predicting and manipulating cone responses to naturalistic inputs. Journal of Neuroscience, 42(7), 1254-1274.
Identification Of Retinal Ganglion Cell Types And Brain Nuclei Expressing The Transcription Factor Brn3c/Pou4f3 Using A Cre Recombinase Knock-in Allele
Parmhans N, Fuller AD, Nguyen E, Chuang K, Swygart D, Wienbar SR, Lin T, Kozmik Z, Dong L, Schwartz GW, Badea TC (2020). Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. Journal of Comparative Neurology. 1-28
Acute Hyperglycemia Reverses Neurovascular Coupling During Dark to Light Adaptation in Healthy Subjects on Optical Coherence Tomography Angiography
Kwan CC, Lee HE, Schwartz G, Fawzi AA. (2020). Acute Hyperglycemia Reverses Neurovascular Coupling During Dark to Light Adaptation in Healthy Subjects on Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. Apr 9;61(4):38.
Caffeine Delays Retinal Neurovascular Coupling during Dark to Light Adaptation in Healthy Eyes Revealed by Optical Coherence Tomography Angiography
Zhang YS, Lee HE, Kwan CC, Schwartz GW, Fawzi AA. (2020). Caffeine Delays Retinal Neurovascular Coupling during Dark to Light Adaptation in Healthy Eyes Revealed by Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. Apr 9;61(4):37.
Molecular Signatures Of Retinal Ganglion Cells Revealed Through Single Cell Profiling
Laboissonniere LA, Goetz JJ, Martin GM, Bi R, Lund TJS, Ellson L, Lynch MR, Mooney B, Wickham H, Liu P, Schwartz GW, Trimarchi JM. (2019). Molecular signatures of retinal ganglion cells revealed through single cell profiling. Sci Rep. Oct 31;9(1):15778.
Hemodynamic Response of the Three Macular Capillary Plexuses in Dark Adaptation and Flicker Stimulation Using Optical Coherence Tomography Angiography
Nesper PL, Lee HE, Fayed AE, Schwartz GW, Yu F, Fawzi AA. (2019). Hemodynamic Response of the Three Macular Capillary Plexuses in Dark Adaptation and Flicker Stimulation Using Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. Feb 1;60(2):694-703. 9.
Review & Viewpoints
Color Vision: More Than Meets The Eye
Schwartz, G.W. (2021). Color vision: More than meets the eye. Current Biology, 31 (15)
Circuits for Feature Selectivity in the Inner Retina (Featured in The Senses: A Comprehensive Reference)
Schwartz, G.W. & Swygart, D. (2020). Circuits for Feature Selectivity in the Inner Retina. in The Senses: A Comprehensive Reference. Ed. Bernd Fritzsch.
Typology and Circuitry of Suppressed-by-Contrast Retinal Ganglion Cells
Jacoby, J., & Schwartz, G. W. (2018). Typology and circuitry of Suppressed-by-Contrast retinal ganglion cells. Frontiers in cellular neuroscience, 12.
The Dynamic Receptive Fields Of Retinal Ganglion Cells
Wienbar, S., & Schwartz, G. (2018). The dynamic receptive fields of retinal ganglion cells. Progress in retinal and eye research.
Nonlinear Spatial Encoding By Retinal Ganglion Cells: When 1 + 1 ≠ 2
Schwartz, G., & Rieke, F. (2011). Nonlinear spatial encoding by retinal ganglion cells: when 1+ 1≠ 2. The Journal of general physiology, 138(3), 283-290.
An Expanding View Of Dynamic Electrical Coupling In The Mammalian Retina
Cafaro, J., Schwartz, G. W., & Grimes, W. N. (2011). An expanding view of dynamic electrical coupling in the mammalian retina. The Journal of physiology, 589(9), 2115-2116
The Retina as Embodying Predictions about the Visual World
Berry, M. J., & Schwartz, G. (2011). The retina as embodying predictions about the visual world. Predictions in the Brain: Using Our Past to Generate a Future, 295.
Gregory Schwartz Articles
*equal contribution
Receptive Field Center-surround Interactions Mediate Context-dependent Spatial Contrast Encoding In The Retina
Turner, M. H., Schwartz, G. W., & Rieke, F. (2018). Receptive field center-surround interactions mediate context-dependent spatial contrast encoding in the retina. eLife, 7, e38841.
Nonlinear Spatiotemporal Integration by Electrical and Chemical Synapses in the Retina
Kuo, S. P., Schwartz, G. W., & Rieke, F. (2016). Nonlinear spatiotemporal integration by electrical and chemical synapses in the retina. Neuron, 90(2), 320-332.
The Synaptic And Circuit Mechanisms Underlying A Change In Spatial Encoding In The Retina
Grimes, W. N.*, Schwartz, G. W.*, & Rieke, F. (2014). The synaptic and circuit mechanisms underlying a change in spatial encoding in the retina. Neuron, 82(2), 460-473.
Interplay Of Cell-autonomous And Non-autonomous Mechanisms Tailors Synaptic Connectivity Of Converging Axons In Vivo
Okawa, H., Della Santina, L., Schwartz, G. W., Rieke, F., & Wong, R. O. (2014). Interplay of cell-autonomous and nonautonomous mechanisms tailors synaptic connectivity of converging axons in vivo. Neuron, 82(1), 125-137.
Visual Space Is Represented by Nonmatching Topographies of Distinct Mouse Retinal Ganglion Cell Types
Bleckert, A., Schwartz, G. W., Turner, M. H., Rieke, F., & Wong, R. O. (2014). Visual space is represented by nonmatching topographies of distinct mouse retinal ganglion cell types. Current Biology, 24(3), 310-315.
Controlling Gain One Photon At A Time
Schwartz, G. W., & Rieke, F. (2013). Controlling gain one photon at a time. Elife, 2, e00467.
Alert Response to Motion Onset in the Retina
Chen, E. Y., Marre, O., Fisher, C., Schwartz, G., Levy, J., da Silveira, R. A., & Berry, M. J. (2013). Alert response to motion onset in the retina. Journal of Neuroscience, 33(1), 120-132.
The Spatial Structure Of A Nonlinear Receptive Field
Schwartz, G. W., Okawa, H., Dunn, F. A., Morgan, J. L., Kerschensteiner, D., Wong, R. O., & Rieke, F. (2012). The spatial structure of a nonlinear receptive field. Nature neuroscience, 15(11), 1572. (Faculty of 1000 recommendation by Brent Doiron)
Low Error Discrimination Using A Correlated Population Code
Schwartz, G.*, Macke, J.*, Amodei, D., Tang, H., & Berry, M. J. (2012). Low error discrimination using a correlated population code. Journal of neurophysiology, 108(4), 1069-1088.
Fine Spatial Information Represented in a Population of Retinal Ganglion Cells
Soo, F. S., Schwartz, G. W., Sadeghi, K., & Berry, M. J. (2011). Fine spatial information represented in a population of retinal ganglion cells. Journal of Neuroscience, 31(6), 2145-2155.
An Oscillatory Circuit Underlying The Detection Of Disruptions In Temporally-periodic Patterns
Gao, J., Schwartz, G., Berry, M. J., & Holmes, P. (2009). An oscillatory circuit underlying the detection of disruptions in temporally-periodic patterns. Network: Computation in Neural Systems, 20(2), 106-135.
Sophisticated Temporal Pattern Recognition in Retinal Ganglion Cells
Schwartz, G., & Berry 2nd, M. J. (2008). Sophisticated temporal pattern recognition in retinal ganglion cells. Journal of neurophysiology, 99(4), 1787-1798.
Synchronized Firing among Retinal Ganglion Cells Signals Motion Reversal
Schwartz, G., Taylor, S., Fisher, C., Harris, R., & Berry II, M. J. (2007). Synchronized firing among retinal ganglion cells signals motion reversal. Neuron, 55(6), 958-969.
(Faculty of 1000 recommendation by Leonard Maler)
Detection And Prediction Of Periodic Patterns By The Retina
Schwartz, G., Harris, R., Shrom, D., & Berry II, M. J. (2007). Detection and prediction of periodic patterns by the retina. Nature neuroscience, 10(5), 552.
(Faculty of 1000 recommendation by Bruce Cumming)
Shadows Of The Past: Temporal Retrieval Effects In Recognition Memory
Schwartz, G., Howard, M. W., Jing, B., & Kahana, M. J. (2005). Shadows of the past: Temporal retrieval effects in recognition memory. Psychological Science, 16(11), 898-904.