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Precision Neuromodulation Lab at Northwestern University conducts translational research in electrophysiology of human mental functions. Our studies fundamentally investigate how neural communications across meso to macroscale levels of brain organization encode cognition and emotions in wellness and disorders. We seek to delineate general neural principles, phenotypes across the population, and functional idiosyncrasies. The Lab’s engineering focus is on developing personalized, adaptive, and closed-loop non-invasive brain stimulation techniques. We augment our neuromodulation implementations (TMS, tACS) with neuroimaging (EEG, MRI), computational head modeling (FEA), and neuronavigated robotics for the most precise stimulation delivery. Our human experimental program includes neuropsychological studies in mood regulation, decision-making, and memory as well as clinical trials in device-based interventional therapies for mental health.