Preprint
Belaghzal H, Borrman T, Stephens AD, Lafontaine DL, Venev SV Weng Z, Marko JF, Dekker J. Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C. Submitted to Nature Genetics. Preprint on bioRxiv. https://www.biorxiv.org/content/10.1101/704957v1
Published
Gladstein S, Almassalha LM, Cherkezyan L, Chandler JE, Eshein A, Eid A, Zhang D, Wu W, Bauer GM, Stephens AD, Morochnik S, Subramanian H, Marko J, Ameer GA, Szleifer I, Backman V. (2018). Multimodal interferometric imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm. Nat Commun. 10(1) 1652. https://www.nature.com/articles/s41467-019-09717-6
Stephens AD*, Liu PZ*, Kandula V, Chen H, Herman C, Almassahla LM, O’Halloran T, Backman V, Adam S, Goldman R, Banigan EJ, Marko JF. (2018). Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation. * co-first authors. Mol Biol Cell E19-05-0286-T. https://www.molbiolcell.org/doi/10.1091/mbc.E19-05-0286
Stephens AD, Banigan EJ, Marko JF. (2019) Chromatin’s physical properties shape the nucleus and its functions. Curr Opin Cell Biol. 58:76-84. https://authors.elsevier.com/c/1YkAi3PA3sD5G3
Biggs R, Liu P, Stephens AD, Marko F. (2019). Effects of altering histone post-translational modifications on mitotic chromosome structure and mechanics. Mol Biol Cell. 30:820-827. https://www.molbiolcell.org/doi/10.1091/mbc.E18-09-0592.
Stephens AD, Liu PZ, Banigan EJ, Almassahla LM, Backman V, Adam S, Goldman R , Marko JF. (2018). Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins. Mol Biol Cell. 29: 220-233. http://www.molbiolcell.org/content/29/2/220.abstract
*** We were also highlighted and got the cover!
Stephens AD, Banigan EJ, Marko JF . (2017). Separate roles for chromatin and lamins in nuclear mechanics. Nucleus. Dec 28:1-6. http://www.tandfonline.com/eprint/XjQ2r86HruFEyHqfHAhu/full
Banigan EJ, Stephens AD, Marko JF. (2017). Mechanics and buckling of biopolymeric shells and cell nuclei. Biophys J. 8: 1654-1663. http://www.sciencedirect.com/science/article/pii/S0006349517309293
Stephens AD, Banigan EJ, Adam S, Goldman R, Marko JF. (2017). Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus. Mol Biol Cell. 28: 1984-1996. http://www.molbiolcell.org/content/28/14/1984.full
Stephens AD, Snider CE, Bloom K. (2015). The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation. Cell Cycle. 14: 2206-2218. http://www.tandfonline.com/doi/full/10.1080/15384101.2015.1046656
Snider CE, Stephens AD, Kirkland JG, Hamdani O, Kamakaka RT, Bloom K. (2014) Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis. J Cell Biol. 201405028. http://jcb.rupress.org/content/early/2014/10/14/jcb.201405028
Verdaasdonk JS, Stephens AD, Haase J, Bloom K. (2014). Bending the rules: widefield microscopy and the Abbe limit of resolution. J Cell Physiol. 229: 132-138. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076117/
Stephens AD, Quammen CW, Chang B, Haase J, Taylor 2nd RM, Bloom K. (2013). The spatial segregation of pericentric cohesin and condensin in the mitotic spindle. Mol Biol Cell. 23: 2560-2570. http://www.molbiolcell.org/content/24/24/3909.full
Stephens AD, Snider CE, Haase J, Haggerty RA, Vasquez PA, Forest GM, Bloom K. (2013). Individual pericentromeres display coordinated motion and stretching in the yeast spindle. J Cell Biol. 203: 407-16. http://jcb.rupress.org/content/early/2013/10/28/jcb.201307104
Haase J, Mishra PK, Stephens A, Haggerty RA, Quammen C, Taylor 2nd RM, Yeh E, Basrai MA, Bloom K. (2013). A 3D map of the yeast kinetochore reveals the presence of core and accessory centromere-specific histone. Curr. Biol. 23: 1939-1944. http://www.sciencedirect.com/science/article/pii/S096098221300972X
Stephens AD, Haggerty RA, Vasquez PA, Vicci L, Snider CE, Shih F, Quammen C, Mullins C, Haase J, Taylor 2nd RM, Verdaasdonk JS, Falvo M, Jin Y, Forest G, Bloom K. (2013). Pericentric chromatin loops function as a nonlinear spring in mitotic force balance. J Cell Biol. 200: 757- 72. http://jcb.rupress.org/content/200/6/757.full
Verdaasdonk JS, Gardner R, Stephens AD, Yeh E, Bloom K. (2012). Tension-dependent nucleosome remodeling at the pericentromere in yeast. Mol Biol Cell. 23: 2560-2570. http://www.molbiolcell.org/content/23/13/2560.full
Haase J, Stephens A, Verdaasdonk J, Yeh E, Bloom K. (2012). Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics. Curr Biol. 22: 471-481. http://www.sciencedirect.com/science/article/pii/S0960982212001248
Stephens AD, Haase J, Vicci L, Taylor 2nd RM, Bloom K. (2011). Cohesin, condensin, and the Intramolecular centromere loop together generate the mitotic chromatin spring. J Cell Biol. 193: 1167-1180. http://jcb.rupress.org/content/193/7/1167.full
Li Z, Vizeacoumar FJ, Bahr S, Li J, Warringer J, Vizeacoumar FS, Min R, VanderSluis B, Bellay J, DeVit M, Fleming JA, Stephens A, et al. (2011). Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nature Biotechnol. 29: 361-367. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286520/
Bekker JM, Colantonio JR, Stephens AD, Clarke WT, King SJ, Hill KL, Crosbie RH. (2007). Direct interaction of Gas11 with microtubules: implications for the dynein regulatory complex. Cytoskeleton. 64: 461-473. https://www.ncbi.nlm.nih.gov/pubmed/17366626
Culver-Hanlon TL, Lex SA, Stephens AD, Quintyne NJ, King SJ. (2006). A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules. Nat Cell Biol. 8: 264. https://www.ncbi.nlm.nih.gov/pubmed/16474384
***A list of publications and citations can be found on my Google Scholar page.