Our manuscript Insights into Nucleosome Organization in Mouse Embryonic Stem Cells through Chemical Mapping is published in Cell.
Featured here is our cover illustration entry for the publication.
This cover was fun to make even though we didn’t get selected!
Caption: The nucleosome landscape of a cell can dramatically influence gene expression patterns. In this issue, Voong et al. develop a chemical biology approach to precisely map nucleosomes across the mammalian genome. The cover depicts the chemical mapping technology as a hot air balloon designed in the likeness of a nucleosome. The scientists on board are charting out the nucleosome landscape with a searchlight powered by reagents that catalyze the hydroxyl radical cleavage of nucleosome centers. The authors would like to dedicate the cover art to their former colleague Jon Widom (1955-2011).
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