Our Mol. Biol. Evol. paper shows that, judging by the transcriptomic response, C. elegans male pheromone ascr#10 feminizes hermaphrodite germline. Unfortunately for the recipient that’s not all…
Author: Denis Faerberg
Serotonin and germline quality
Our Developmental Biology paper reports that pharmacological stimulation of serotonin signaling improves oocyte quality in C. elegans and D. melanogaster. Click on the title for press release. https://news.northwestern.edu/stories/2023/05/happy-worms-have-healthy-eggs/
Sex-specificity of the C. elegans metabolome
The effort led by the Schroeder Lab (Cornell) is now published in Nature Communications. In collaboration with the Lee (Cornell) and Portman (Rochester) Labs, we documented hundreds of male-specific metabolites in C. elegans males.
Serotonergic circuit regulates reproductive behavior and germline development
Our Proc. Biol. Sci. paper elaborated the serotonergic circuit that regulates several reproductive behaviors and germline proliferation.
Male-specific metabolites in C. elegans
We collaborated with the Schroeder lab (Cornell) effort to characterize all male-specific metabolites in C. elegans (see the bioRxiv preprint).
Serotonergic circuit regulates reproduction and germline
We released a bioRxiv preprint which shows that a specific serotonergic circuit coordinately regulates reproductive behaviors and germline development in C. elegans.
Male pheromone improves oogenic germline
In a PNAS paper we showed how C. elegans male pheromone improves the quality of the oogenic germline.