List of publications indexed in PubMed​ by ​the Ma Laboratory

Pereira Luppi M, Azcorra M, Caronia-Brown G, Poulin JF, Gaertner Z, Gatica S, Moreno-Ramos OA, Nouri N, Dubois M, Ma YC, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Cicchetti F, Dombeck DA, Awatramani R. Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins. Cell Reports. 2021 Nov 9;37(6):109975. doi: 10.1016/j.celrep.2021.109975. PubMed PMID: 34758317; PMCID: PMC8607753.

Xu Z, Ma A, Ma YC. RNA methylation preserves ES cell identity by chromatin silencing of retrotransposons. Signal Transduction and Targeted Therapy. 2021 Jul 7;6(1):258. doi: 10.1038/s41392-021-00683-4. PubMed PMID: 34234099; PMCID: PMC8263629.

Qiao A, Zhou J, Xu S, Ma W, Boriboun C, Kim T, Yan B, Deng J, Yang L, Zhang E, Song Y, Ma YC, Richard S, Zhang C, Qiu H, Habegger KM, Zhang J, Qin G. Sam68 promotes hepatic gluconeogenesis via CRTC2. Nature Communications. 2021 Jun 7;12(1):3340. doi: 10.1038/s41467-021-23624-9. PubMed PMID: 34099657; PMCID: PMC8185084.

Deng HX, Zhai H, Shi Y, Liu G, Lowry J, Liu B, Ryan ÉB, Yan J, Yang Y, Zhang N, Yang Z, Liu E, Ma YC, Siddique T. Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS. Communications Biology. 2021 Mar 25;4(1):396. doi: 10.1038/s42003-021-01942-4. PubMed PMID: 33767386; PMCID: PMC7994668.

Ryan ÉB, Yan J, Miller N, Dayanidhi S, Ma YC, Deng HX, Siddique T. Early death of ALS-linked CHCHD10-R15L transgenic mice with central nervous system, skeletal muscle, and cardiac pathology. iScience. 2021 Feb 19;24(2):102061. doi: 10.1016/j.isci.2021.102061. eCollection 2021 Feb 19. PubMed PMID: 33659869; PMCID: PMC7890413.

Hsu PJ, Shi H, Zhu AC, Lu Z, Miller N, Edens BM, Ma YC, He C. The RNA-binding protein FMRP facilitates the nuclear export of N⁶-methyladenosine-containing mRNAs. Journal of Biological Chemistry. 2019 Dec 27;294(52):19889-19895. doi: 10.1074/jbc.AC119.010078. Epub 2019 Nov 21. PubMed PMID: 31753916; PMCID: PMC6937581.

Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. FMRP Modulates Neural Differentiation through m⁶A-Dependent mRNA Nuclear Export. Cell Reports. 2019 Jul 23;28(4):845-854.e5. doi: 10.1016/j.celrep.2019.06.072. PubMed PMID: 31340148; PMCID: PMC6687293.

Gao X, Xu J, Chen H, Xue D, Pan W, Zhou C, Ma YC, Ma L. Defective Expression of Mitochondrial, Vacuolar H⁺-ATPase and Histone Genes in a C. elegans Model of SMA.Frontiers in Genetics. 2019;10:410. doi: 10.3389/fgene.2019.00410. eCollection 2019. PubMed PMID: 31130987; PubMed Central PMCID: PMC6509145.

Edens BM, Yan J, Deng HX, Siddique T, Ma YC. 2017. A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis. eLIFE, pii: e25453. doi: 10.7554/eLife.25453. (PMID: 28463112)​

Shi H, Deng HX, Gius D, Schumacker PT, Surmeier DJ, Ma YC. 2017. Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress. Human Molecular Genetics, 15; 26(10): 1915-1926. doi:10.1093/hmg/ddx100. (PMID: 27488123)

Miller N, Shi H, Zelikovich AS, Ma YC. 2016. Motor Neuron Mitochondrial Dysfunction in Spinal Muscular Atrophy. Human Molecular Genetics, 15;25(16):3395-3406. doi:10.1093/hmg/ddw262. Epub 2016 Aug 3. (PMID: 27488123). Nature Reviews Neurology Research Highlight on this article: Malkki H. 2016. Mitochondrial dysfunction could precipitate motor neuron loss in spinal muscular atrophy. Nature Reviews Neurology, 12(10):556. (PMID: 27562548)

Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, Xu Y, Chan P, Huang B, Gao XP, Song Z, Liu Z, Fecto F, Siddique N, Foroud T, Jankovic J, Ghetti B, Nicholson DA, Krainc D, Melen O, Vance JM, Pericak-Vance MA, Ma YC, Rajput AH, Siddique T. 2016. Identification of TMEM230 mutations in familial Parkinson’s disease. Nature Genetics, 48(7):733-9. doi: 10.1038/ng.3589. (PMID: 27270108)

Edens BM, Miller N, Ma YC. 2016. Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration. Frontiers in Cellular Neuroscience, 10:44. doi: 10.3389/fncel.2016.00044. (PMID: 26973461)

Miller N, Feng Z, Edens BM, Yang B, Shi H, Sze CC, Hong BT, Su SC, Cantu JA, Topczewski J, Crawford TO, Ko CP, Sumner CJ, Ma L, Ma YC. 2015. Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. Journal of Neuroscience, 35(15):6038-50. (PMID: 25878277) (Cover Article)

Nouri N, Patel MJ, Joksimovic M, Poulin JF, Anderegg A, Taketo MM, Ma YC, Awatramani R. 2015. Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors. Molecular and Cellular Neurosciences, 68:131-142. doi: 10.1016/j.mcn.2015.07.002. (PMID: 26164566)

Edens BM, Ajoud-Driss S, Ma L, Ma YC. 2014. Molecular mechanisms and animal models of spinal muscular atrophy. Biochimica et Biophysica Acta, pii: S0925-4439(14)00244-0. (PMID: 25088406)

Ma YC, Song MR, Park JP, Ho HH, Hu L, Kurtev M, Zieg J, Ma Q, Pfaff SL,Greenberg ME. 2008. Regulation of motor neuron specification by GSK3-mediated phosphorylation of Neurogenin 2. Neuron, 58:65-77. (PMID: 18400164). NeuronPreviews on this paper: Lai HC, Johnson JE. 2008. Neurogenesis or Neuronal Specification: Phosphorylation Strikes Again! Neuron, 58:3-5. (PMID: 18400155)

Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW, Dikkes P, Korsmeyer SJ, Greenberg ME. 2002. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. Developmental Cell, 3(5): 631-43. (PMID: 12431371)

Lowry WE, Huang J, Ma YC, Ali S, Wang D, Williams DM, Okada M, Cole PA,Huang XY. 2002. Csk, a critical link of protein signals to actin cytoskeletal reorganization. Developmental Cell, 2(6): 733-44. (PMID: 12062086)

Zheng B*, Ma YC*, Ostrom RS, Insel PA, Huang XY, Farquhar MG. 2001. RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. Science, 294:1939-42. (*Equal contribution) (PMID: 11729322). Science Perspectives on this paper: Zastrow MV, Mostov K. 2001. A new thread in an intricate web. Science, 294:1845-47 (PMID: 11729293)

Ma YC, Huang J, Ali S, Lowry W, Huang XY. 2000. Src tyrosine kinase is a novel direct effector of G proteins. Cell, 102: 635-646. (PMID: 11007482)