2016

Guo Y, Klüppel M, Tang H, Tan S, Zhang P, Chen Z. Lentivirus-mediated transfection of chondroitinase ABC gene without the bacterial leader sequence enables long-term secretion of functional chondroitinase ABC in human bone marrow stromal cells. Biotechnol Lett. 2016 Feb 24. [Epub ahead of print]

2014

Willis CM, Klüppel M. Chondroitin sulfate-E is a negative regulator of a pro-tumorigenic Wnt/beta-catenin-Collagen 1 axis in breast cancer cells. PLoS One. 2014 Aug 4;9(8).

Prinz RD, Willis CM, van Kuppevelt TH, Klüppel M. Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. PLoS One. 2014 Mar 25;9(3)

2012

Willis, C.M., Kluppel, M. Inhibition by chondroitin sulfate-E can specify functional Wnt/β-catenin signaling thresholds in NIH3T3 fibroblasts. J Biol Chem. 2012 Aug 22.

Klüppel, M., Samavarchi-Tehrani, P., Liu, K., Wrana, J.L., Hinek, A. C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome. Eur J Hum Genet. 2012 Aug;20(8):870-7.

2011

Klüppel, M. (2011). Efficient secretion of biologically active Chondroitinase ABC from mammalian cells in the absence of a N-terminal signal peptide. Mol. Cell.

Prinz RD, Willis CM, Viloria-Petit A, Klüppel M. Elimination of breast tumor-associated chondroitin sulfate promotes metastasis. Genet Mol Res. 2011 Dec 8;10(4):3901-13.

2009

Willis, C.M., Wrana J.L. and Klüppel, M. (2009) Identification and characterization of TGFβ-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 Genet. Mol. Res. 8 (4): 1331-1343.