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Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like Polymers

Publications

Sub-50 fs Formation of Charge Transfer States Rules the Fate of Photoexcitations in Eumelanin-Like Materials 
 
Vasilis Petropoulos, Alexandra Mavridi-Printezi, Arianna Menichetti, Dario Mordini, Piotr Kabacinski, Nathan C. Gianneschi, Marco Montalti,* Margherita Maiuri,* and Giulio Cerullo.* Journal of Physical Chemistry Letters, 2024, XXXX, XXX, XXX−XXX. DOI: 10.1021/acs.jpclett.4c00170
Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like Polymers. 
 
Kendal P. Carrow, Haylee L. Hamilton, Madeline P. Hopps, Yang Li, Baofu Qiao, N. Connor Payne, Matthew P. Thompson, Xiaoyu Zhang, Assa Magassa, Mara Fattah, Shivangi Agarwal, Michael P. Vincent, Marina Buyanova, Paul A. Bertin, Ralph Mazitschek, Monica Olvera de la Cruz, Delinda A. Johnson, Jeffrey A. Johnson, Nathan C. Gianneschi. Advanced Materials, 2024, 2311467. DOI: /10.1002/adma.202311467
 
This work was highlighted in the press! 
Topical application of synthetic melanin promotes tissue repair. 
 
Dauren Biyashev, Zofia E. Siwicka, Ummiye V. Onay, Michael Demczuk, Dan Xu, Madison K. Ernst, Spencer T. Evans, Cuong V. Nguyen, Florencia A. Son, Navjit K. Paul, Naneki C. McCallum, Omar K. Farha, Stephen D. Miller, Nathan C. Gianneschi, Kurt Q. Lu. npj Regen Med 2023, 8, 61. DOI: /10.1038/s41536-023-00331-1.
 
This work was highlighted in the press! 
Ultrafast Xanthate‐Mediated Photoiniferter Polymerization‐Induced Self‐Assembly (PISA).
 
Bowman, J. I.; Eades, C. B.; Vratsanos, M. A.; Gianneschi, N. C.; Sumerlin, B. S. Angew Chem Int Ed 2023, e202309951. DOI: 10.1002/anie.202309951.

Thrombospondin-1 Proteomimetic Polymers Exhibit Anti-Angiogenic Activity in Models of Neovascular Age-Related Macular Degeneration.

Choi, W.†; Nensel, A. K.†;Droho, S.; Fattah, M. A.; Mokashi-Punekar, S.; Swygart, D.; Burton, S. T.; Schwartz, G; Lavine, J.; Gianneschi, N. Sci. Adv. 2023, 9 (41), eadi8534. DOI: 10.1126/sciadv.adi8534.
 
This work was highlighted by the Northwestern IIN !

Enzyme-Responsive Nanoparticles for the Targeted Delivery of an MMP Inhibitor to Acute Myocardial Infarction

Holly Sullivan, Yifei Liang, Kendra Worthington, Colin Luo, Nathan Gianneschi, Karen L. Christman. Biomacromolecules, 2023, XXXX, XXX, XXX-XXX. DOI: 10.1021/acs.biomac.3c0042.

Exploration of Organic Nanomaterials with Liquid-Phase Transmission Electron Microscopy

Joanna Korpanty, Nathan C. Gianneschi. Acc. Chem. Res. 2023, 56, 17, 2298–2312. DOI: 10.1021/acs.accounts.3c00211.

The Role of Experimental Noise in a Hybrid Classical-Molecular Computer to Solve Combinatorial Optimization Problems

Veronica K. Krasecki, Abhishek Sharma, Andrew C. Cavell, Christopher Forman, Si Yue Guo, Evan Thomas Jensen, Mackinsey A. Smith, Rachel Czerwinski, Pascal Friederich, Riley J. Hickman, Nathan Gianneschi, Alán Aspuru-Guzik, Leroy Cronin*, and Randall H. Goldsmith*. ACS Cent. Sci. 2023, 9, 7, 1453–1465. DOI: 10.1021/acscentsci.3c00515. 

Enzyme-Responsive Nanoparticles for Dexamethasone Targeted Delivery to Treat Inflammation in Diabetes

Nathan Schiffmann, Yifei Liang, Carlos E. Nemcovsky, Michal Almogy, Michal Halperin-Sternfeld, Nathan C. Gianneschi, Lihi Adler-Abramovich, Eyal Rosen. Adv Healthcare Materials 2023, 2301053. DOI: 10.1002/adhm.202301053.

Upper Critical Solution Temperature Polymer Assemblies via Variable Temperature Liquid Phase Transmission Electron Microscopy and Liquid Resonant Soft X-Ray Scattering

Joanna Korpanty, Cheng Wang, and Nathan C. Gianneschi. Nat Commun. 2023, 14 (1), 3441. DOI: 10.1038/s41467-023-38781-2
 

Metal-Organic Frameworks with a Bioinspired Porous Polymer Coating for Sieving Separation

Shengyi Su, Xuhao Zhou, Xinyi Gong, Karam Idrees, Kent Kirlikovali, Timur Islamoglu, Omar Farha, Nathan Gianneschi. J. Am. Chem. Soc, 2023, 145 (24) 13195–13203. DOI: 10.1021/jacs.3c02195. 

Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Yifei Liang, Holly L. Sullivan, Kendal Carrow, Joshua M. Mesfin, Joanna Korpanty, Kendra Worthington, Colin Luo, Karen L. Christman, Nathan C. Gianneschi. J. Am. Chem. Soc. 2023, 145, 20, 11185–11194. DOI: 10.1021/jacs.3c01054

Mechanism of Structural Colors in Binary Mixtures of Nanoparticle-based Supraballs

Christian M. Heil, Anvay Patil, Bram Vanthournout, Saranshu Singla, Markus Bleuel, Jing-Jin Song, Ziying Hu, Nathan C. Gianneschi, Matthew D. Shawkey, Sunil K. Sinha, Arthi Jayaraman*, and Ali Dhinojwala.* Sci. Adv. 2023, 9 (21), eadf2859.  DOI: 10.1126/sciadv.adf2859.

Gradient Copolymer Synthesis through Self-Assembly

Georg M. Scheutz, Jared I. Bowman, Swagata Mondal, Julia Y. Rho, John B. Garrison, Joanna Korpanty, Nathan C. Gianneschi, and Brent S. Sumerlin.* ACS Macro Lett. 2023, 12, XXX, 454–461. DOI: 10.1021/acsmacrolett.3c00148

Ouzo Effect Examined at the Nanoscale via Direct Observation of Droplet Nucleation and Morphology

Maria A. Vratsanos, Wangyang Xue, Nathan D. Rosenmann, Lauren D. Zarzar, Nathan C. Gianneschi*, ACS Cent. Sci.2023, DOI: 10.1021/acscentsci.2c01194

Biomimetic Pheomelanin to Unravel the Electronic, Molecular and Supramolecular Structure of the Natural Product

Wei Cao, Haochuan Mao, Naneki C. McCallum, Xuhao Zhou, Hao Sun, Christopher Sharpe, Joanna Korpanty, Ziying Hu, Qing Zhe Ni, Michael D. Burkart, Matthew D. Shawkey, Michael R. Wasielewski, Nathan C. Gianneschi. Chem. Sci., 2023,14, 4183-4192. DOI: 10.1039/D2SC06418A 

Statistical Copolymer Metal Organic Nanotubes

Jacob A. Barrett, Nathan D. Rosenmann, Karthikeyan Gnanasekaran, Xian B. Carroll, Nathan C. Gianneschi*, and David M. Jenkins*, Chem. Sci., 2023,14, 1003-1009. DOI: 10.1039/D2SC06084A

Intravascularly Infused Extracellular Matrix Biomaterial for Targeting and Treating Inflammatory Tissues

Martin Spang, Ryan Middleton, Miranda Diaz, Jervaughn Hunter, Joshua Mesfin, Alison Banka, Holly Sullivan, Raymond Wang, Tori Lazerson, Saumya Bhatia, James Corbitt, Gavin D’Elia, Gerardo Sandoval, Rebecca Kandell, Maria Vratsanos, Karthikeyan Gnanasekaran, Takeyuki Kato, Sachiyo Igata, Colin Luo, Kent Osborn, Nathan Gianneschi, Omolola Eniola-Adefeso, Pedro Cabrales, Ester Kwon, Francisco Contijoch, Ryan Reeves, Anthony N. DeMaria, Karen Christman*, Nature BME2022, DOI: 10.1038/s41551-022-00964-5

Self-Assembly of Tunable Intrinsically Disordered Peptide Amphiphiles

Tamara Ehm, Hila Shinar, Guy Jacoby, Sagi Meir, Gil Koren, Merav Segal Asher, Joanna Korpanty, Matthew P. Thompson, Nathan C. Gianneschi, Michael M. Kozlov, Salmoa Emma Azoulay-Ginsburg, Roey J. Amir*, Joachim O. Rädler*, Roy Beck*, Biomacromolecules2022, DOI: 10.1021/acs.biomac.2c00866.

Hydrophobic Melanin via Post-Synthetic Modification for Controlled Self-Assembly

Xuhao Zhou, Shengyi Su, Bram Vanthournout, Ziying Hu, Florencia A. Son, Kexin Zhang, Zofia E. Siwicka, Xinyi Gong, Navjit Paul, Karthikeyan Gnanasekaran, Christopher Forman, Omar K. Farha, Matthew D. Shawkey*, and Nathan C. Gianneschi*, ACS Nano2022, DOI: 10.1021/acsnano.2c08114

Single-Crystalline Imine-Linked Two-Dimensional Covalent Organic Frameworks Separate Benzene and Cyclohexane Efficiently

Anusree Natraj, Woojung Ji, Junjie Xin, Ioannina Castano, David Burke, Austin Evans, Michael Strauss, Mohamed Ateia, Leslie Hamachi, Nathan C. Gianneschi, Zeid ALOthman, Junliang Sun, Kareem Yusuf, William Dichtell*, JACS2022, DOI: 10.1021/jacs.2c07166

Using Nanoscopic Solvent Defects for Spatial and Temporal Manipulation of Single Assemblies of Molecules

Soumik Das, JungHyun Noh, Wei Cao, Hao Sun, Nathan C. Gianneschi*, Nicholas Abbott*, ACS Nano Lett.2022, DOI: 10.1021/acs.nanolett.2c02454

Modeling Structural Colors from Disordered One-Component Colloidal Nanoparticle-based Supraballs using Combined Experimental and Simulation Techniques

Anvay Patil, Christian M. Heil, Bram Vanthournout, Saranshu Singla, Ziying Hu, Jan Ilavsky, Nathan C. Gianneschi, Matthew D. Shawkey, Sunil K. Sinha, Arthi Jayaraman*, and Ali Dhinojwala*, ACS Materials Lett.2022, DOI: 10.1021/acsmaterialslett.2c00524.

Aggregation-Suppressed Porous Processable Hexa-Zirconium/Polymer Compsites for Detoxification of a Nerve Agent Simulant

 Shengyi Su, Dahee Jung, Xinyi Gong, Karam Idrees, Sylvia Hanna, Timur Islamoglu, Nathan C. Gianneschi*, Omar Farha*, Chem. Mater.2022, DOI: 10.1021/acs.chemmater.2c00262.

Rapid Generation of Metal-Organic Framework Phase Diagrams by High-Throughput Transmission Electron Microscopy

Xinyi Gong, Karthikeyan Gnanasekaran, Kaikai Ma, Christopher Forman, Xingjie Wang, Shengyi Su, Omar Farha, Nathan C. Gianneschi*, J. Am. Chem. Soc2022, DOI: 10.1021/jacs.2c01095.

Direct Observation of Emulsion Morphology, Dynamics, and Demulsification

Maria A. Vratsanos, Nathan C. Gianneschi*, ACS Nano2022, DOI: 10.1021/acsnano.2c00199

Mussel Adhesive-Inspired Proteomimetic Polymer

Or Berger, Claudia Battistella, Yusu Chen, Julia Oktawiec, Zofia E. Siwicka, Danielle Tullman-Ercek, Muzhou Wang, Nathan C. Gianneschi* J. Am. Chem. Soc2022, DOI: 10.1021/jacs.1c10936

Organic Solution-Phase Transmission Electron Microscopy of Copolymer Nanoassembly Morphology and Dynamics

Joanna Korpanty, Karthikeyan Gnanasekaran, Cadapakam Venkatramani, Nanzhi Zang, Nathan C. Gianneschi* Cell Reports Physical Science2022, DOI: 10.1016/j.xcrp.2022.100772.

Featured in Cell Reports Physical Science Editors Choice, 2022

Stimuli-Responsive Liquid Crystal Printheads for Spatial and Temporal Control of Polymerization

Xin Wang†, Hao Sun†, Young-Ki Kim, Daniel B. Wright, Michael Tsuei, Nathan C. Gianneschi,* Nicholas L. Abbott* Adv. Mater.2022, DOI: 10.1002/adma.202106535.

Interfacial Polyelectrolyte–Surfactant Complexes Regulate Escape of Microdroplets Elastically Trapped in Thermotropic Liquid Crystals

Michael Tsuei, Hao Sun, Young-Ki Kim, Xin Wang, Nathan C. Gianneschi*, Nicholas L. Abbott* Langmuir2022, DOI: 10.1021/acs.langmuir.1c02580.

Structural Color Production in Melanin-Based Disordered Colloidal Nanoparticle Assemblies in Spherical Confinement

Anvay Patil, Christian M. Heil, Bram Vanthournout, Markus Bleuel, Saranshu Singla, Ziying Hu, Nathan C. Gianneschi, Matthew D. Shawkey, Sunil K. Sinha, Arthi Jayaraman*, Ali Dhinojwala*; Adv. Optical Mater.2021, DOI: 10.1002/adom.202102162

Controlled n-Doping of Naphthalene-Diimide-Based 2D Polymers

Austin M. Evans, Kelsey A. Collins, Sangni Xun, Taylor G. Allen, Samik Jhulki, Ioannina Castano, Hannah L. Smith, Michael J. Strauss, Alexander K. Oanta, Lujia Liu, Lei Sun, Obadiah G. Reid, Gjergji Sini, Danilo Puggioni, James M. Rondinelli, Tijana Rajh, Nathan C. Gianneschi, Antoine Kahn, Danna E. Freedman, Hong Li, Stephen Barlow, Garry Rumbles, Jean-Luc Brédas, Seth R. Marder, William R. Dichtel*; Adv. Mater.2021, DOI: 10.1002/adma.202101932

Stimuli Induced Uptake of Protein-Like Peptide Brush Polymers

Angela Blum*, Jian Yin, Jacqueline Kammeyer, Matthew Thompson, Michael Gilson, Helen Lin, Blayne Oliver, Nathan C. Gianneschi* Chem. Eur. J.2021, DOI: 10.1002/chem.202103438

Thermoresponsive Polymer Assemblies via Variable Temperature Liquid-Phase Transmission Electron Microscopy and Small Angle X-ray Scattering

Joanna Korpanty, Lucas R. Parent, Nicholas Hampu, Steven Weigand,and Nathan C. Gianneschi* Nature Comm.2021, DOI: 10.1038/s41467-021-2673-z

On the Origin of Proteolytic Stability of Peptide-Brush Polymers as Globular Proteomimetics

Hao Sun, Baofu Qiao, Wonmin Choi, Nicholas Hampu, Naneki C. McCallum, Matthew P. Thompson, Julia Oktawiec, Steven Weigand, Omar M. Ebrahim, Monica Olvera de la Cruz*,and Nathan C. Gianneschi* ACS Cent. Sci.2021, DOI: 10.1021/acscentsci.1c01149.

Dipeptide Nanostructure Assembly and Dynamics via in Situ Liquid-Phase Electron Microscopy

Karthikeyan Gnanasekaran, Joanna Korpanty, Or Berger, Nicholas Hampu, Michal Halperin-Sternfeld, Dana Cohen-Gerassi, Lihi Adler-Abramovich, and Nathan C. Gianneschi* ACS Nano.2021, DOI: 10.1021/acsnano.1c06130

Non-Iridescent Structural Color Control via Inkjet Printing of Self-Assembled Synthetic Melanin Nanoparticles

Ziying Hu†, Nathan Bradshaw†, Bram Vanthournout, Chris Forman, Karthik Gnanasekeran, Matthew Thompson, Paul Smeets, Ali Dhinojwala, Matthew Shawkey, Mark Hersam*, Nathan Gianneschi.* Chem. Mater.2021, DOI: 10.1021/acs.chemmater.1c01719

The Evolution of Darker Wings in Seabirds in Relation to Temperature-Dependent Flight Efficiency

Svana Rogalla†*, Michaël P. J. Nicolaï†*, Sara Porchetta†, Gertjan Glabeke, Claudia Battistella, Liliana D’Alba, Nathan C. Gianneschi, Jeroen van Beeck and Matthew D. Shawkey. J. R. Soc. Interface.2021, DOI: 10.1098/rsif.2021.0236.

Glycopolymer Microarrays with Sub-Femtomolar Avidity for Glycan Binding Proteins Prepared by Grafted-To/Grafted-From Photopolymerizations

Daniel J. Valles, Yerzhan Zholdassov, Joanna Korpanty, Samiah Uddin, Yasir Naeem, David R. Mootoo, Nathan C. Gianneschi, Adam B Braunschweig*. Angew. Chem.2021, DOI: 10.1002/anie.202105729.

Innovations in Disease State Responsive Soft Materials for Targeting Extracellular Stimuli Associated with Cancer, Cardiovascular Disease, Diabetes, and Beyond

Claudia Battistella†​, Yifei Liang†, Nathan C. Gianneschi* Adv. Mater, 2021DOI: 10.1002/adma.202007504

Degradable Polymers via Olefin Metathesis Polymerization

Hao Sun†​, Yifei Liang†, Matthew Thompson, Nathan Gianneschi* Prog. Polym. Sci, 2021. DOI: 10.1016/j.progpolymsci.2021.101427

A Molecular Computing Approach to Solving Optimization Problems via Programmable Microdroplet Arrays 

Si Yue Guo, Pascal Friederich, Yudong Cao, Tony C Wu, Christopher J Forman, Douglas Mendoza, Matthias Degroote, Andrew Cavell, Veronica Krasecki, Riley J Hickman, Abhishek Sharma, Leroy Cronin*, Nathan Gianneschi, Randall H Goldsmith, Alán Aspuru-Guzik* Matter, 2021DOI: 10.1016/j.matt.2021.03.002

Anisotropic Synthetic Allomelanin Materials via Solid State Polymerization of Self-Assembled 1,8-Dihydroxynaphthalene Dimers

Xuhao Zhou, Xinyi Gong, Wei Cao, Christopher J. Forman, Julia Oktawiec, Liliana D’ Alba, Hao Sun, Matthew P. Thompson, Ziying Hu, Utkarsh Kapoor, Naneki C. McCallum, Christos D. Malliakas, Omar K. Farha, Arthi Jayaraman, Matthew D. Shawkey and Nathan C. Gianneschi* Angew. Chemie. Int. Ed., 2021DOI: 10.1002/anie.202103447

Hydrogel Formation with Enzyme-Responsive Cyclic Peptides

Andrea S. Carlini,† Mary F. Cassidy,† Nathan C. Gianneschi*, “Peptide Macrocycles: Methods and Protocols”, 2021. ISBN: 978-1-0716-1689-5

Allomelanin: A Biopolymer of Intrinsic Microporosity

Naneki C. McCallum, Florencia A. Son, Tristan D. Clemons, Steven J. Weigand, Karthikeyan Gnanasekaran, Claudia Battistella, Brooke E. Barnes, Hashanthi Abeyratne-Perera, Zofia E. Siwicka, Christopher J. Forman, Xuhao Zhou, Martin H. Moore, Daniel A. Savin, Samuel I. Stupp, Zheng Wang, Gary J. Vora, Brandy J. Johnson, Omar K. Farha, and Nathan C. Gianneschi*, J. Am. Chem. Soc., 2021. DOI: 10.1021/jacs.1c00748.

Orthogonal Images Concealed Within a Responsive 6-Dimensional Hypersurface

Yerzhan Zholdassov, Daniel Valles, Samiha Uddin, Joanna Korpanty, Nathan Gianneschi, and Adam Braunschweig*, Adv. Mater., 2021. DOI: 10.1002/adma.202100803

Synthetic Porous Melanin

Zofia E. Siwicka, Florencia A. Son, Claudia Battistella, Martin H. Moore, Joanna Korpanty, Naneki C. McCallum, Zheng Wang, Brandy J. Johnson, Omar K. Farha, and Nathan C. Gianneschi, J. Am. Chem. Soc., 2021. DOI: 10.1021/jacs.0c10465.

Mapping Grains, Boundaries, and Defects in 2D Covalent Organic Framework Thin Films

Ioannina Castano, Austin Evans, Roberto dos Reis, Vinayak Dravid, Nathan Gianneschi, William Dichtel.  Chem. Mater., 2021. DOI: 10.1021/acs.chemmater.0c04382.

Transient Catenation in a Zirconium-Based Metal–Organic Framework and Its Effect on Mechanical Stability and Sorption Properties

Lee Robison, Xinyi Gong, Austin M. Evans, Florencia A. Son, Xingjie Wang, Louis R. Redfern, Megan C. Wasson, Zoha H. Syed, Zhijie Chen, Karam B. Idrees, Timur Islamoglu, Massimiliano Delferro, William R. Dichtel, François-Xavier Coudert, Nathan C. Gianneschi*, and Omar K. Farha*.  J. Am. Chem. Soc., 2021. DOI: 10.1021/jacs.0c11266

Targeted Nanoscale Therapeutics for Myocardial Infarction

Holly L. Sullivan, Nathan C. Gianneschi*, and Karen L. Christman*. Biomater. Sci, 2021. DOI: 10.1039/D0BM01677B

Probing Thermoresponsive Polymerization-Induced Self-Assembly with Variable-Temperature Liquid-Cell Transmission Electron Microscopy

Georg M. Schuetz, Mollie A. Touve, Andrea S. Carlini, John B. Garrison, Karthikeyan Gnanasekaran, Brent S. Sumerlin, and Nathan C. Gianneschi.* Matter, 2020. DOI: 10.1016/j.matt.2020.11.017

Unraveling the Structure and Function of Melanin through Synthesis

Wei Cao, Xuhao Zhou, Naneki McCallum, Zihying Hu, Qing Ni, Utkarsh Kapoor, Christian Heil, Kristine Cay, Tara Zand, Alex Mantanona, Arthi Jayaraman, Ali Dhinojwala, Dimitri Deheyn, Matthew Shawkey, Michael Burkart, Jeffrey Rinehart, Nathan Gianneschi.  J. Am. Chem. Soc., 2021. DOI: 10.1021/jacs.0c12322.

pH-Responsive Charge-Conversion Progelator Peptides

Andrea S. Carlini*, Wonmin Choi, Naneki C. McCallum, and Nathan C. Gianneschi*. Adv. Funct. Mater. 2021, 2007733. DOI: 10.1002/adfm.202007733.

High Efficiency Loading of Micellar Nanoparticles with a Light Switch for Enzyme-Induced Rapid Release of Cargo

Wonmin Choi, Claudia Batistella, and Nathan C. Gianneschi*. Biomat. Science, 2021. DOI: 10.1039/d0bm01713b

100th Anniversary of Macromolecular Science Viewpoint: Polymeric Materials by In Situ Liquid-Phase Transmission Electron Microscopy

Lucas R. Parent, Karthikeyan Gnanasekaran, Joanna Korpanty, and Nathan C. Gianneschi*.  ACS Macro Lett. 2021, 10, XXX, 14-38DOI: 10.1021/acsmacrolett.0c00595

Structurally Colored Inks from Synthetic Melanin-Based Crosslinked Supraparticles

Ziying Hu, Hao Sun, Matthew P. Thompson, Ming Xiao, Michael C. Allen, Xuhao Zhou, Qing Zhe Ni, Zhao Wang, Weiyao Li, Michael D. Burkart*, Dimitri D. Deheyn*, Ali Dhinojwala*, Matthew D. Shawkey*, and Nathan C. Gianneschi*.  ACS Materials Lett., 2021, 3, XXX, 50–55DOI: 10.1021/acsmaterialslett.0c00432

Electronically Coupled 2D Polymer/MoS2 Heterostructures

Halleh B. Balch, Austin M. Evans, Raghunath R. Dasari, Hong Li, Ruofan Li, Simil Thomas, Danqing Wang, Ryan P. Bisbey, Kaitlin Slicker, Ioannina Castano, Sangni Xun, Lili Jiang, Chenhui Zhu, Nathan Gianneschi, Daniel C. Ralph, Jean-Luc Bredas, Seth R. Marder, William R. Dichtel, Feng Wang. JACS., 2020, DOI: 10.1021/jacs.0c10151

Characterization of Broadband Complex Refractive Index of Synthetic Melanin Coatings and Their Changes after Ultraviolet Irradiation

Weiyao Li, Anvay Patil, Xuhao Zhou, Zhao Wang, Ming Xiao, Matthew D. Shawkey, Nathan C. Gianneschi*, Ali Dhinojwala*. Appl. Phys. Lett. 117, 203701 2020, DOI: 10.1063/5.0024229

Cyclic (Alkyl)(Amino)Carbene (CAAC) Gold(I) Complexes as Chemotherapeutic Agents

Maria T. Proetto, Kelsey Alexander, Mohand Melaimi, Guy Bertrand, Nathan C. Gianneschi. Chem. Eur., 2020, DOI: 10.1002/chem.202004317.

Bioinspired Chemoenzymatic Route to Artificial Melanin for Hair Pigmentation

Claudia Battistella, Naneki McCallum, Bram Vanthournout, Christopher Forman, Qing Zhe Ni, James La Clair, Michael Burkart, Matthew Shawkey, Nathan Gianneschi. Chem. Mat., 2020, 32 (21), 9201–9210. DOI: 10.1021/acs.chemmater.0c02790.

Insights into the Structure and Dynamics of Metal-Organic Frameworks via Transmission Electron Microscopy

Xinyi Gong, Karthikeyan Gnanasekaran, Zhijie Chen, Lee Robison, Megan C. Wasson, Kyle C. Bentz, Seth M. Cohen*, Omar K. Farha*, Nathan C. Gianneschi.*  J. Am. Chem. Soc., 2020142 (41), 17224–17235. DOI: 10.1021/jacs.0c08773

Inside PolyMOFs: Layered Structures in Polymer-Based Metal-Organic Frameworks

Kyle C. Bentz, Karthikeyan Gnanesekaran, Jake B. Bailey, Sergio Ayala, Jr., F. Akif Tezcan, Nathan C. Gianneschi*, Seth M. Cohen.*  Chem. Sci, 2020, 11, 10523-10528. DOI: 10.1039/D0SC03651J.

Lucas R. Parent, Maria Vratsanos, Biao Jin, James J. De Yoreo, Nathan C. Gianneschi.  MRS Bulletin, 2020, 45 (9) , 727-737. DOI: 10.1557/mrs.2020.224.

Enzyme-Directed Functionalization of Designed, Two-Dimensional Protein Lattices

Rohit Subramanian, Yuta Suzuki, Lorillee Tallorin, Swagat Sahu, Matthew P. Thompson, Nathan C. Gianneschi, Michael Burkart, F. Akif Tezcan.* ACS Biochemistry, 2020, DOI: 10.1021/acs.biochem.0c00363.


Yijun Xie, Kelsey A. Krug, Kristine S. Cay, Mark Kalaj, Naneki C. McCallum, Zofia E. Siwicka, Zhao Wang, Nathan C. Gianneschi, Michael D. Burkart, Jeffrey D. Rinehart.*
CCS Chemistry, 2020, 2, 1483–1490. DOI: 10.:31635/ccschem.020.202000307.

 Degradable Polyphosphoramidate via Ring-Opening Metathesis Polymerization

Yifei Liang, Hao Sun,* Wei Cao, Matthew P. Thompson, Nathan C. Gianneschi.* ACS Macro Lett.20209 (10), 1417–1422. DOI: 10.1021/acsmacrolett.0c00401.

 

 

Proapoptotic Peptide Brush Polymer Nanoparticles via Photoinitiated Polymerization-Induced Self-Assembly

Hao Sun, Wei Cao, Nanzhi Zang,Tristan D. Clemons, Georg M. Scheutz, Ziying Hu, Matthew P. Thompson, Yifei Liang, Maria Vratsanos, Xuhao Zhou, Wonmin Choi, Brent S. Sumerlin, Samuel Stupp, Nathan C. Gianneschi.* Angew. Chemie. Int. Ed. 2020, DOI: 10.1002/anie.202006385

Selenomelanin: An Abiotic Selenium Analogue of Pheomelanin

Wei Cao, Naneki C. McCallum, Qing Zhe Ni, Weiyao Li, Hannah Boyce, Haochuan Mao, Xuhao Zhou, Hao Sun, Matthew P. Thompson, Claudia Battistella, Michael R. Wasielewski, Ali Dhinojwala, Matthew D. Shawkey,* Michael D. Burkart,* Zheng Wang, * Nathan C. Gianneschi.* J. Am. Chem. Soc.2020142 (29), 12802–12810. DOI: 10.1021/jacs.0c05573.

Self-Assembly of Macromolecules within Single Topological Defects of Nematic Solvents

JungHyun Noh, Wei Cao, Hao Sun, Yu Yang, Nathan C. Gianneschi,* Nicholas Abbott.* Chem. Mater., 202032 (15), 6753–6764. DOI: 10.1021/acs.chemmater.0c02415.

Radical-Enriched Artificial Melanin

Wei Cao, Alex J. Mantanona, Haochuan Mao, Naneki C. McCallum, Yang Jiao, Claudia Battistella, Valeria Caponetti, Nanzhi Zang, Matthew P. Thompson, Marco Montalti, J. Fraser Stoddart, Michael R. Wasielewski, Jeffrey D. Rinehart,* Nathan C. Gianneschi.* Chem. Mater., 202032 (13), 5759–5767. DOI: 10.1021/acs.chemmater.0c01573.

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In Situ Monitoring of the Seeding and Growth of Silver Metal-Organic Nanotubes by Liquid-Cell Transmission Electron Microscopy

Karthikeyan Gnanasekaran, Kristina M. Vailonis, David M. Jenkins,* Nathan C. Gianneschi.* ACS Nano, 202014 (7), 8735–8743. DOI: 10.1021/acsnano.0c03209

Complex Nanoparticle Diffusional Motion in Liquid Cell Transmission Electron Microscopy

Evangelos Bakalis, Lucas Parent, Maria Vratsanos, Chiwoo Park, Nathan C. Gianneschi, Francesco Zerbetto.* J. Phys. Chem C, 2020124 (27), 14881–14890. DOI: 10.1021/acs.jpcc.0c03203.

In Situ Ni2+ Stain for Liposome Imaging by Liquid-Cell Transmission Electron Microscopy

Karthikeyan Gnanasekaran, HanByul Chang, Paul J. M. Smeets, Joanna Korpanty, Franz M. Geiger,* Nathan C. Gianneschi.* Nano Letters, 202020 (6), 4292–4297. DOI: 10.1021/acs.nanolett.0c00898.

Printing a Wide Gamut of Saturated Structural Colors Using Binary Mixtures, With Applications in Anticounterfeiting

Mario Echeverri, Anvay Patil, Ziying Hu, Matthew D. Shawkey, Nathan C. Gianneschi, Ali Dhinojwala.* ACS Appl. Mater. Interfaces, 2020,12 (17), 19882–19889. DOI: 10.1021/acsami.0c01449.

Paclitaxel-terminated peptide brush polymers

Jialei Zhu, Hao Sun, Cassandra E. Callmann, Matthew P. Thompson, Claudia Battistella, Maria T. Proetto, Andrea S. Carlini, Nathan C. Gianneschi.* Chem. Comm., 2020, 56, 6778-6781. DOI: 10.1039/C9CC10023G.

Biomolecular Densely Grafted Brush Polymers: Oligonucleotides, Oligosaccharides and Oligopeptides

Wonmin Choi, Hao Sun, Claudia Battistella, Or Berger, Maria Vratsanos, Max Wang, Nathan C. Gianneschi.* Angew. Chemie Int. Ed., 2020. DOI: 10.1002/anie.202005379

Mimicking Natural Human Hair Pigmentation with Synthetic Melanin

 Claudia Battistella, Naneki C. McCallum, Karthikeyan Gnanasekaran, Xuhao Zhou, Valeria Caponetti, Marco Montalti, Nathan C. Gianneschi.* ACS Central Science, 2020, 6 (7), 1179–1188. DOI: 10.1021/acscentsci.0c00068

Click here for ACS First Reactions article describing this work: Drop the Toxins! Bioinspired Hair Dye Offers a Safer Alternative

Multicolor Polymeric Nanoparticle Neuronal Tracers

 Nanzhi Zang, John B. Issa, Treffly B. Ditri, Dante S. Bortone, Mollie A. Touve, Anthony M. Rush, Massimo Scanziani, Daniel A. Dombeck, Nathan C. Gianneschi.* ACS Central Science, 2020, 6 (3), 436-445. DOI:1 0.1021/acscentsci.0c00027

Phase Transitions in Metal-Organic Frameworks Directly Monitored through In Situ Variable Temperature Liquid-Cell Transmission Electron Microscopy and In Situ X-Ray Diffraction

Jiafei Lyu, Xinyi Gong, Seung-Joon Lee, Karthikeyan Gnanasekaran, Xuan Zhang, Megan Wasson, Xingjie Wang, Peng Bai, Xianghai Guo, Nathan Gianneschi,* Omar Farha.* Journal of the American Chemical Society, 2020, 142 (10), 4609–4615. DOI: 10.1021/jacs.0c00542.

Polymer Brush Hypersurface Photolithography

Carlos Carbonell, Daniel Valles, Alexa M. Wong, Andrea S. Carlini, Mollie A. Touve, Joanna Korpanty, Nathan C. Gianneschi, Adam B. Braunschweig.* Nature Communications, 2020, 11, 1244. DOI: 10.1038/s41467-020-14990-x.

Acid Exfoliation of Imine-linked Covalent Organic Frameworks Enables Solution Processing into Crystalline Thin Films 

David W. Burke, Chao Sun, Ioannina Castano, Nathan C. Flanders, Austin M. Evans, Edon Vitaku, David C. McLeod, Robert H. Lambeth, Lin X. Chen, Nathan C. Gianneschi, William R. Dichtel.* Angewandte Chemie, 2020, 132 (13), 5203-5209. DOI: 10.1002/ange.201913975. 

Optical Monitoring of Polymerizations in Droplets with High Temporal Dynamic Range 

Andrew C. Cavell, Veronica K. Krasecki, Guoping Li, Abhishek Sharma, Hao Sun, Matthew P. Thompson, Christopher J. Forman, Si Yue Guo, Riley J. Hickman, Katherine A. Parrish, Alan Aspuru-Guzik, Leroy Cronin, Nathan C. Gianneschi, Randall H. Goldsmith.* Chemical Science, 2020, 11, 2647-2656. DOI: 10.1039/c9sc05559b.

Poly(peptide): Synthesis, Structure, and Function of Peptide-Polymer Amphiphiles and Protein-like Polymers

Cassandra Callmann, Matthew Thompson, Nathan Gianneschi.* Accounts of Chemical Research, 2020. 53 (2) 400-413. DOI: 10.1021/acs.accounts.9b00518.

Single Crystals of Electrically Conductive Two-Dimensional Metal-Organic Frameworks: Structural and Electrical Transport Properties

Robert Day, D. Kwabena Bediako, Mehdi Rezaee, Lucas Parent, Grigorii Skorupskii, Maxx Arguilla, Christopher Hendon, Ivo Stassen, Nathan Gianneschi, Philip Kim, Mircea Dinca.* ACS Central Science, 2019, 5 (12), 1959-1964. DOI: 10.1021/acscentsci.9b01006.

Emissive Single-Crystalline Boroxine-Linked Colloidal Covalent Organic Frameworks

Austin Evans, Ioannina Castano, Alexandra Brumberg, Lucas Parent, Amanda Corcos, Rebecca Li, Nathan Flanders, David Gosztola, Nathan Gianneschi, Richard Schaller, William Dichtel.* Journal of the American Chemical Society, 2019, 141 (50), 19728-19735. DOI: 10.1021/jacs.9b08815.

The Mechanism of UVA Degradation of Synthetic Melanin

Weiyao Li, Zhao Wang, Ming Xiao, Toshikazu Miyoshi, Xiaozhou Yang, Ziying Hu, Cheng Liu, Steven S.C. Chuang, Matthew Shawkey, Nathan Gianneschi, Ali Dhinojwala.* Biomacromolecules, 2019, 20 (12), 4593-4601. DOI: 10.1021/acs.biomac.9b01433.

Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme-Directed Assembly

Claudia Battistella, Cassandra E. Callmann, Matthew P. Thompson, Shiyin Yao, Anjana V. Yeldandi, Tomoko Hayashi, Dennis A. Carson, Nathan C. Gianneschi.* Advanced Healthcare Materials, 2019, 1901105. DOI: 10.1002/adhm.201901105.

Chemical Control Over Nucleation and Anisotropic Growth of Two Dimensional Covalent Organic Frameworks

Ioannina Castano, Austin Evans, Haoyuan Li, Edon Vitaku, Michael Strauss, Jean-Luc Brédas,* Nathan Gianneschi,* William Dichtel.* ACS Central Science2019, 5 (11), 1892-1899. DOI: 10.1021/acscentsci.9b00944.


Mollie A. Touve, Andrea S. Carlini, Nathan Gianneschi.
* Nature Communications2019, 10, 4837. DOI: 10.1038/s41467-019-12660-1


Hao Sun, Wonmin Choi, Nanzhi Zang, Claudia Battistella, Matthew P. Thompson, Wei Cao, Xuhao Zhou, Christopher Forman, Nathan Gianneschi.
* Angewandte Chemie2019, 58, 2-8. DOI:10.1002/ange.201908634

Andrea Carlini, Mollie Touve, Héctor Fernández-Caro, Matthew Thompson, Mary Cassidy, Wei Cao, Nathan Gianneschi.* Faraday Discuss2019, 219, 44-57. DOI: 10.1039/C9FD00026G.

Xuhao Zhou, Naneki C. McCallum, Ziying Hu, Wei Cao, Karthikeyan Gnanasekaran, Yuanning Feng, J. Fraser Stoddart, Zhao Wang,* Nathan Gianneschi.* ACS Nano, 2019. DOI: 10.1021/acsnano.9b02160.

Experimental and Theoretical Evidence for Molecular Forces Driving Surface Segregation in Photonic Colloidal Assemblies

Ming Xiao, Ziying Hu, Thomas E. Gartner III, Xiaozhou Yang, Weiyao Li, Arthi Jayaraman,* Nathan C. Gianneschi,* Matthew D. Shawkey,* Ali Dhinojwala.* Science Advances, 2019, 5 (9), eaax1254DOI: 10.1126/sciadv.aax1254.

 Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin

Cassandra E. Callmann, Clare L. M. LeGuyader, Spencer T. Burton, Matthew P. Thompson, Robert Hennis, Christopher Barback, Niel M. Henriksen, Warren C. Chan, Matt J. Jaremko, Jin Yang, Arnold Garcia, Michael D. Burkart, Michael K. Gilson, Jeremiah D. Momper, Paul A. Bertin, Nathan C. Gianneschi*, J. Am. Chem. Soc., 2019, 141 (30), 11765-11769. DOI: 10.1021/jacs.9b04272

Efficient Delivery of a Gene Editing Protein to Stem Cells via Peptide Brush Polymers

Angela Blum, David Nelles, Francisco Hidalgo, Mollie Touve, Deborah Sim, Assael A. Madrigal, Gene Yeo,* Nathan C. Gianneschi.* Angewandte Chemie2019, DOI: 10.1002/anie.201904894

Block Copolymer Amphiphile Phase Diagrams by High-Throughput Transmission Electron Microscopy

Mollie A. Touve, Daniel B. WrightChen Mu, Hao Sun, Chiwoo Park, Nathan C. Gianneschi*, Macromolecules, 2019DOI: 10.1021/acs.macromol.9b00563

Kristina Vailonis, Karthikeyan Gnanasekaran, Xian Powers, Nathan Gianneschi*, David Jenkins*,  Journal of the American Chemical Society, 2019, 141 (26), 10177-10182. DOI: 10.1021/jacs.9b04586

Fluorous-Phase Iron Oxide Nanoparticles as Enhancers of Acoustic Droplet Vaporization of Perfluorocarbons with Supra-Physiologic Boiling Point

Alexander M. Vezeridis, Caroline de Gracia Lux, Sarah A. Barnhill, Sejung Kim, Zhe Wu, Sungho Jin, Jacques Lux, Nathan C. Gianneschi,* Robert F. Mattrey,* Journal of Controlled Release, 2019, 302, 54-62 DOI: 10.1016/jconrel.2019.03.013

Spatiotemporal Control Over the Host-Guest Characteristics of a Stimulus-Triggerable Trifunctional Polymer Assembly

Piyachai Khomein, Kingshuk Duttta, Karthikeyan Gnanasekaran, Nathan C. Gianneschi, S. Thayumanavan, Polymer Chemistry2019, 10 (12), 1423-1430 DOI: 10.1039/c8py01788c

Entropic Effects Enable Life at High Temperatures

Young Hun Kim, Geoffray Leriche, Karthik Diraviyam, Takaoki Koyanagi, Kafu Gao, David Onofrei, Joseph Patterson, Anirvan Guha, Nathan C. Gianneschi, Gregory P. Holland, Michael K. Gilson, Michael Mayer, David Sept, Jerry Yang*, Science Advances, 2019, 5 (5). DOI: 10.1126/sciadv.aaw4783

One-pot Universal Initiation-Growth Methods from a Liquid Crystalline Block Copolymer

Bixin Jin, Koki Sano, Satoshi Aya, Yasuhiro Ishida, Nathan Gianneschi, Yunjun Luo,* Xiaoyu Li,* Nature Communications2019, 10.2397 DOI: 10.1038/s41467-019-10341-7

Design and Synthesis of Two-Dimensional Covalent Organic Frameworks with Four-Arm Cores: Prediction of Remarkable Ambipolar Charge-Transport Properties

Simil Thomas, Hong Li, Raghunath R. Dasari, Austin M. Evans, Ioannina Castano, Taylor G. Allen, Obadiah G. Reid, Garry Rumbles, William R. Dichtel, Nathan C. Gianneschi, Seth R. Marder*, Veaceslav Coropceanu*, Jean-Luc Brédas*, Materials Horizons, 2019 DOI: 10.1039/c9mh00035f

Bacterial Model Membranes Deform (resp. Persist) Upon Ni2+ Binding to Inner Core (resp. O-Antigen) of Lipopolysaccharides

HanByul Chang, Karthikeyan Gnanasekaran, Nathan C. Gianneschi*, and Franz M. Geiger,* J.Phys. Chem. B., 2019, 123 (19), 4258-4270 DOI: 10.1021/acs.jpcb.9b0262 

 Enzyme-Induced Kinetic Control of Peptide-Polymer Micelle Morphology

Daniel B. Wright, Abelardo Ramírez-Hernández, Mollie A. Touve, Andrea S. Carlini, Matthew P. Thompson, Joseph P. Patterson, Juan J. de Pablo*, & Nathan C. Gianneschi*, ACS Macro Letters, 2019, 8 (6), 676-681 DOI: 10.1021/acsmacrolett.8b00887

Enzyme-Responsive Progelator Cyclic Peptides for Minimally Invasive Delivery to the Heart Post-Myocardial Infarction

Andrea S. Carlini, Roberto Gaetani, Rebecca L. Braden, Colin Luo, Karen L. Christman* & Nathan C. Gianneschi*, Nature Communications2019, 10, 1735 DOI: 10.1038/s41467-019-09587-y

Ring-Opening Metathesis Polymerization-Induced Self-Assembly (ROMPISA) of a Cisplatin Analogue for High Drug-Loaded Nanoparticles

Daniel B. Wright, Maria T. Proetto, Mollie A. Touve, Nathan C. Gianneschi* Polymer Chemistry2019 DOI:10.1039/c8py01539b.

 

Recent Advances in Amphiphilic Polymer-Oligonucleotide Nanomaterials via Living/Controlled Polymerization Technologies

Hao Sun, Lu Yang, Matthew Thompson, Steve Schara, Wei Cao, Wonmin Choi, Ziying Hu, Nanzhi Zang, Weihong Tan, Nathan Gianneschi* Bioconjugate Chemistry, 2019 DOI: 10.1021/acs.bioconjchem.9b00166

Interrogating Kinetic versus Thermodynamic Topologies of Metal-Organic Frameworks via Combined Transmission Electron Microscopy and X-ray Diffraction Analysis

Xinyi Gong, Hyunho Noh, Nathan Gianneschi*, Omar Farha*, Journal of the American Chemical Society, 2019, 141 (15). DOI: 10.1021/jacs.9b01789

Controlled Growth of Imine-Linked Two-Dimensional Covalent Organic Framework Nanoparticles

Rebecca Li, Nathan C. Flanders, Austin Evans, Woojung Ji, Ioannina Castano, Lin Chen, Nathan Gianneschi,
William Dichtel* Chemical Science, 2019, 10 (13), 3796-3801 DOI: 10.26434/chemrxiv.7604642.v1

Bait-and-Switch Supramolecular Strategy to Generate Noncationic RNA-Polymer Complexes for RNA Delivery

Ziwen Jiang, Wei Cui, Priyaa Prasad, Mollie A. Touve, Nathan C. Gianneschi,* Jesse Mager,* and S. Thayumanavan*, Biomacromolecules, 2019, 20 (1), 435-442 DOI: 10.1021/acs.biomac.8b01321

Jeanne E. Lemaster, Zhao Wang, Ali Hariri, Fang Chen, Ziying Hu, Yuran Huang, Christopher V. Barback, Richard Cochran, Nathan C. Gianneschi,* and Jesse V. Jokerst,* Chem. Mater.201931 (1), 251–259 DOI: 10.1021/acs.chemmater.8b04333

Lorillee Tallorin, JiaLei Wang, Woojoo E. Kim, Swagat Sahu, Nicolas M. Kosa, Pu Yang, Matthew P. Thompson, Michael K. Gilson, Peter I. Frazier,* Michael D. Burkart,* and Nathan C. Gianneschi* Nature Communications, 2018, 9, 5253 DOI: 10.1038/s41467-018-07717-6

 

 

Lucas R. Parent, David Onofrei, Dian Xue, Dillan Stengel, John D. Roehling, J. Bennett Addison, Christopher Forman, Samrat A. Amin, Brian R. Cherry, Jeffery L. Yarger, Nathan C. Gianneschi,* and Gregory P. Holland* Proc. Natl. Acad. Sci., 2018,  DOI: 10.1073/pnas.1810203115

*Photo Credit: Holland Lab, SDSU

Maria T. Proetto, Cassandra E. Callmann, John Cliff, Craig J. Szymanski, Dehong Hu, Stephen B. Howell, James E. Evans, Galya Orr, and Nathan C. Gianneschi* ACS Central Science, 2018, ASAP, DOI: 10.1021/acscentsci.8b00444

Daniel B. Wright, Matthew P. Thompson, Mollie A. Touve, Andrea S. Carlini and Nathan C. Gianneschi*, Macromolecular Rapid Communications, 2019, 40, 1800467, DOI: 10.1002/marc.201800467

Geraldine Polidoa, Xiangyan Shi, Dian Xu, Chengchen Guo, Rich Thai, Joseph P. Patterson, Nathan C. Gianneschi, Thomas M. Suchyna, Frederick Sachs, and Gregory P. Holland*, BBA Biomembranes2019, 1861 (1), 151-160, DOI: 10.1016/j.bbamem.2018.08.004

Austin M. Evans, Lucas R. Parent, Nathan C. Flanders, Ryan P. Bisbey, Edon Vitaku, Matthew S. Kirschner1, Richard D. Schaller, Lin X. Chen, Nathan C. Gianneschi, and William R. Dichtel* Science, 2018, 360 (6395), 3618–3622, DOI: 10.1126/science.aar7883

Geoffray Leriche, Arash Manafirad, Steven Nguyen, Nia Bell, Joseph Patterson, Sankaran Thayumanavan, Jerry Yang, Anthony Dinsmore, and Nathan C. Gianneschi* Chemistry of Materials, 2018, 30 (11), 3618–3622, DOI: 10.1021/acs.chemmater.8b00992

Young-Ki Kim, Yuran Huang, Michael Tsuei, Xin Wang, Nathan C. Gianneschi,* and Nicholas L. Abbott* ChemPhysChem, 2018, 19 (16), 2037–2045,DOI: 10.1002/cphc.201800106

Mollie A. Touve, Adrian C. Figg, Daniel B. Wright, Chiwoo Park, Joshua Cantlon, Brent Sumerlin,* and Nathan C. Gianneschi* ACS Central Science, 2018, 4 (5), 543–547, DOI: 10.1021/acscentsci.8b00148

Daniel B. Wright, Mollie A. Touve, Matthew P. Thompson, and Nathan C. Gianneschi* ACS Macro Letters, 2018, 7, 401–405, DOI: 10.1021/acsmacrolett.8b00091

Lisa Adamiak, Joel Pendery, Jiawei Sun, Kazuki Iwabata, Nathan C. Gianneschi,* and Nicholas Abbott* Macromolecules, 2018, 51 (5), 1978–1985, DOI: 10.1021/acs.macromol.7b02140

Michael S Denny, Jr., Lucas R. Parent, Joseph P. Patterson, Santosh Kumar Meena, Huy Pham, Patricia Abellan, Quentin M. Ramasse, Francesco Paesani, Nathan C. Gianneschi,* and Seth M. Cohen* J. Am. Chem. Soc., 2018, 140 (4), 1348–1357, DOI: 10.1021/jacs.7b10453

Lucas R. Parent, Evangelos Bakalis, Maria Proetto, Yiwen Li, Chiwoo Park, Francesco Zerbetto, and Nathan C. Gianneschi* Acc. Chem. Res., 2018, 51 (1), 3–11, DOI: 10.1021/acs.accounts.7b00331

Alexander Roloff, David A. Nelles, Matthew P. Thompson, Gene W. Yeo, and Nathan C. Gianneschi* Bioconjugate Chemistry, 2018, 29 (1), 126–135, DOI: 10.1021/acs.bioconjchem.7b00657

Lucas R. Parent, Evangelos Bakalis, Abelardo Ramírez-Hernández, Jacquelin K. Kammeyer, Chiwoo Park, Juan de Pablo, Francesco Zerbetto, Joseph P. Patterson, and Nathan C. Gianneschi* J. Am. Chem. Soc., 2017, 139 (47), 17140–17151, DOI: 10.1021/jacs.7b09060

*Watch Micelles Fuse in Real Time

Celia C. Homyak, Ann Fernandez, Mollie A. Touve, Bo Zhao, Francesca Anson, Jeanne A. Hardy, Richard W. Vachet, Nathan C. Gianneschi,* Jennifer L. Ross,* and S. Thayumanavan* Biomacromolecules, 2018, 19 (1), 132–140, DOI: 10.1021/acs.biomac.7b01300

Alexander Roloff,* Andrea S. Carlini, Cassandra E. Callmann, and Nathan C. Gianneschi*J. Am. Chem. Soc., 2017, 139 (46), 16442–16445, DOI: 10.1021/jacs.7b07799

Lucas R. Parent, Huy Pham, Joseph P. Patterson, Michael S Denny, Jr., Seth M. Cohen,* Nathan C. Gianneschi,* and Francesco Paesani* J. Am. Chem. Soc., 2017, 139 (40), 13973–13976, DOI: 10.1021/jacs.7b06585

Lisa Adamiak, Mollie A. Touve, Clare L. M. LeGuyader, and Nathan C. Gianneschi* ACS Nano, 2017, 11 (10), 9877–9888, DOI: 10.1021/acsnano.7b03686

Zhao Wang, Fabio Carniato, Yijun Xie, Yuran Huang, Yiwen Li, Sha He, Nanzhi Zang, Jeffrey D. Rinehart,* Mauro Botta,* and Nathan C. Gianneschi.* Small, 2017, 13 (43), DOI: 10.1002/smll.201701830

Ming Xiao, Ziying Hu, Zhao Wang, Yiwen Li, Alejandro Diaz Tormo, Nicolas Le Thomas, Boxiang Wang, Nathan C. Giannneschi,* Matthew D. Shawkey,* and Ali Dhinojwala.* Science Advances, 2017, 3 (9), e1701151, DOI: 10.1126/sciadv.1701151

Ming Xiao, Matthew D. Shawkey, and Nathan C. Gianneschi* Chem, 2017, 3, 17–30, DOI: 10.1016/j.chempr.2017.06.020

**Commentary on recent, 2017 Ulijn group contribution in Science

Zhao Wang, Yijun Xie, Yiwen Li, Yuran Huang, Lucas R. Parent, Treffly Ditri, Nanzhi Zang, Jeffrey D. Rinehart,* and Nathan C. Gianneschi*
Chemistry of Materials, 2017, 29 (19), 8195–8201, DOI: 10.1021/acs.chemmater.7b02262

Daniel B. Wright, Mollie A. Touve, Lisa Adamiak, and Nathan C. Gianneschi* ACS Macro Letters, 2017, 6 (9), 925-929, DOI: 10.1021/acsmacrolett.7b00408

 

Jessica Ungerleider, Jacquelin Kammeyer, Rebecca L Braden, Karen L Christman,* and Nathan C. Gianneschi* Polymer Chemistry, 2017, 8 (34), 5212-5219, DOI: 10.1039/C7PY00568G

 

Yuran Huang, Yiwen Li , Ziying Hu, Xiujun Yue, Maria T. Proetto, Ying Jones, and Nathan C. Gianneschi* ACS Cent. Sci., 2017, 3(6), 564–569, DOI: 10.1021/acscentsci.6b00230

 

Swagat Sahu, Po Ling Cheung, Charles W. Machan, Steven A. Chabolla, Clifford P. Kubiak,* and Nathan C. Gianneschi* Chem. Eur. J., 2017, 23, 1–5, DOI: 10.1002/chem.201701901

 

Cassandra E. Callmann and Nathan C. Gianneschi* Biomedical Nanotechnology, Protocol, 2017, 1570, 223–238, DOI: 10.1007/978-1-4939-6840-4_15

 

Steven Chabolla, Charles W. Machan, Jian Yin, Edward A. Dellamary, Swagat Sahu, Nathan C. Gianneschi, Michael K. Gilson, Faik A. Tezcan, Clifford P. Kubiak* Faraday Discussions, 2017, 198, 279–300, DOI: 10.1039/C7FD00003K

 

Geoffray Leriche, Jessica L. Cifelli, Kevin C. Sibucao, Joseph P. Patterson, Takaoki Koyanagi, Nathan C. Gianneschi, and Jerry Yang* 

Org. Biomol. Chem., 2017, 15, 2157–2162, DOI: 10.1039/C6OB02832B

 

Brian Smith, Lucas Parent, Anna Overholts, Peter Beaucage, Ryan Bisbey, Anton Chavez, Nicky Hwang, Chiwoo Park, Austin Evans, Nathan C. Gianneschi,* William Dichtel* ACS Central Science, 2017, 3 (1), 58–65, DOI: 10.1021/acscentsci.6b00331

 

Yuran Huang, Alexander Vezeridis, James Wang, Zhao Wang, Matthew Thompson, Robert Mattrey, and Nathan C. Gianneschi*
J. Am. Chem. Soc., 2017, 139 (1), 15–18, DOI: 10.1021/jacs.6b08800

 

Yiwen Li, Yijun Xie, Zhao Wang, Nanzhi Zang, Fabio Carniato, Yuran Huang, Christopher M. Andolina, Lucas R. Parent, Treffly B. Ditri, Eric D. Walter, Mauro Botta, Jeffrey D. Rinehart,* and Nathan C. Gianneschi* ACS Nano, 2016, 10 (11), 10186–10194, DOI: 10.1021/acsnano.6b05502

 

Mark E. Johnson, Judy Shon, Brian M. Guan, Joseph P. Patterson, Nathan J. Oldenhuis, Alexander C. Eldredge, Nathan C. Gianneschi, and Zhibin Guan* Bioconjugate Chemistry, 2016, 27 (8), 17849–1788, DOI: 10.1021/acs.bioconjchem.6b00216

 

Ming Xiao, Yiwen Li, Jiuzhou Zhao, Zhao Wang, Min Gao, Nathan C. Gianneschi*, Ali Dhinojwala*, and Matthew D. Shawkey*
Chemistry of Materials, 2016, 28 (15), 5516–5521, DOI: 10.1021/acs.chemmater.6b02127

 

Andrea S. Carlini, Lisa Adamiak, and Nathan C. Gianneschi* Macromolecules, 2016, 49 (12), 4379–4394, DOI: 10.1021/acs.macromol.6b00439

 

Joseph P. Patterson, Lucas R. Parent, Joshua Cantlon, Holger Eickhoff, Guido Bared, James E. Evans, and Nathan C. Gianneschi*
Microscopy and Microanalysis, 2016, 22 (3), 507–514, DOI: 10.1017/S1431927616000659

 

Maria T. Proetto, Christopher R. Anderton, Dehong Hu, Craig J. Szymanski, Zihua Zhu, Joseph P. Patterson, Jacquelin Kammeyer, Lizanne G. Nilewski, Anthony M. Rush, Nia C. Bell, James E. Evans, Galya Orr, Stephen B. Howell, and Nathan C. Gianneschi*
ACS Nano, 2016, 10 (4), 4046–4054, DOI: 10.1021/acsnano.5b06477

 

Lyndsay M. Randolph, Clare L. M. LeGuyader, Michael E. Hahn, Christopher M. Andolina, Joseph P. Patterson, Robert F. Mattrey, Jill E. Millstone, Mauro Botta, Miriam Scadeng, Nathan C. Gianneschi* Chemical Science, 2016, 7, 4230–4236, DOI: 10.1039/C6SC00342G

 

Daniel B. Wright, Joseph P. Patterson, Nathan C. Gianneschi, Christophe Chassenieux, Oliver Colombani, and Rachel K. O’Reilly*
Polymer Chemistry, 2016, 7, 1577–1583, DOI: 10.1039/C5PY02006A

 

Joseph Patterson*, Douglas Collins, Jennifer Michaud, Jessica Axson, Camille Sultana,Trever Moser, Abigail Dommer, Jack Conner, Vicki Grassian, M. Stokes, Grant Deane, James Evans, Michael Burkart, Kimberly Prather, Nathan C. Gianneschi
ACS Central Science, 2016, 2 (1), 40–47, DOI: 10.1021/acscentsci.5b00344

 

Kevin B. Daniel, Cassandra E. Callmann, Nathan C. Gianneschi* and Seth M. Cohen* Chemical Communications, 2016, 52, 2126–2128, DOI: 10.1039/C5CC09164K

 

Angela P. Blum, Jacqueline K. Kammeyer, Nathan C. Gianneschi* Chemical Science, 2016, 7, 989–994, DOI: 10.1039/C5SC03417E

 

Kate M. Veccharelli, Venus K. Tong, Jennifer L. Young, Jerry Yang*, and Nathan C. Gianneschi* Chemical Communications, 2016, 52, 567–570, DOI: 10.1039/C5CC07882B

 

Joseph P. Patterson, Maria T. Proetto, and Nathan C. Gianneschi* Perspectives in Science, 2015, 6, 106–112, DOI: 10.1016/j.pisc.2015.10.003

 

Yiwen Li, Yuran Huang, Zhao Wang, Fabio Carniato, Yijun Xie, Joseph P. Patterson, Matthew P. Thompson, Christopher M. Andolina, Treffly B. Ditri, Jill E. Millstone, Joshua S. Figueroa, Jeffrey D. Rinehart, Miriam Scadeng, Mauro Botta, and Nathan C. Gianneschi* Small, 2015, 12 (5), 668–677, DOI: 10.1002/smll.201502754

 

Zhao Wang, Yiwen Li, Yuran Huang, Matthew P. Thompson, Clare L. M. LeGuyader, Swagat Sahu, and Nathan C. Gianneschi*
Chemical Communications, 2015, 51, 17108–17111, DOI: 10.1039/C5CC05653E

 

C. Derek Ma, Lisa Adamiak, Daniel S. Miller, Xiaoguang Wang, Nathan C. Gianneschi* and Nicholas L. Abbott*
Small, 2015, 11 (43), 5722, DOI: 10.1002/smll.201502137

Daniel B. Wright, Joseph P. Patterson, Anaïs Pitto-Barry, Annhelen Lu, Nigel Kirby, Nathan C. Gianneschi, Christophe Chassenieux, Olivier Colombani, and Rachel K. O’Reilly* Macromolecules, 2015, 48 (18), 6516–6522, DOI: 10.1021/acs.macromol.5b01426

 

Nia C. Bell, Samantha J. Doyle, Giulia Battistelli, Clare L. M. LeGuyader, Matthew P. Thompson; Ambata M. Poe, Arnold Rheingold, Curtis Moore, Marco Montalti, S. Thayumanavan, Michael J. Tauber, Nathan C. Gianneschi* Langmuir, 2015, 31 (35), 9707–9717, DOI: 10.1021/acs.langmuir.5b01822

 

Mary M. Nguyen, Andrea S. Carlini, Miao-Ping Chien, Sonya Sonnenberg, Colin Luo, Rebecca L. Braden, Kent G. Osborn, Yiwen Li, Nathan C. Gianneschi*, and Karen L. Christman* Advanced Materials, 2015, 27 (37), 5547–5552, DOI: 10.1002/adma.201502003

 

Cassandra E. Callmann, Christopher V. Barback, Matthew P. Thompson, David J. Hall, Robert F. Mattrey, and Nathan C. Gianneschi
Advanced Materials, 2015, 27 (31) 4611–4615, DOI:10.1002/adma.201501803

 

Joseph P. Patterson, Patricia Abellan, Michael S. Denny, Jr., Chiwoo Park, Nigel D. Browning, Seth M. Cohen, James E. Evans, and Nathan C. Gianneschi*  J. Am. Chem. Soc., 2015, 137 (23), 7322–7328, DOI: 10.1021/jacs.5b00817

 

Ming Xiao, Yiwen Li, Michael Allen, Dimitri Deheyn, Xiujun Yue, Juizhou Zhao, Nathan Gianneschi, Matthew Shawkey, and Ali Dhinojwala
ACS Nano, 2015, 9 (5), 5454–5460, DOI:10.1021/acsnano.5b01298

 

Mary M. Nguyen, Nathan C. Gianneschi, and Karen L. Christman Current Opinion in Biotechnology, 2015, 34, 225-231, DOI:10.1016/j.copbio.2015.03.016/ma502163j

 

Anthony M. Rush, Carrie R. James, Nathan C. Gianneschi
Handbook of Metathesis-Polymer Synthesis, 2015, 3 (Ch.6), 116–145, Editors: Robert. H. Grubbs and Ezat Khosravi, ISBN: 978-3-527-33950-1

 

Sarah A. Barnhill, Nia C. Bell, Joseph P. Patterson, Daniel P. Olds, and Nathan C. Gianneschi* Macromolecules, 2015, 48 (4), 1152–1161, DOI: 10.1021/ma502163j

 

Angela P. Blum, Jacquelin K. Kammeyer, Anthony M. Rush, Cassandra E. Callmann, Michael E. Hahn, Nathan C. Gianneschi*
J. Am. Chem. Soc., 2014, Perspective 137 (6), 2140–2140, DOI: 10.1021/ja510147n

 

Ti-Hsuan Ku, Swagat Sahu, Nicolas M. Kosa, Kevin M. Pham, Michael D. Burkart, and Nathan C. Gianneschi
J. Am. Chem. Soc., 2014, 136 (50), 17378–17381, DOI: 10.1021/ja509827s

 

Angela P. Blum, Jacquelin K. Kammeyer, Jian Yin, Dustin T. Crystal, Anthony M. Rush, Michael K. Gilson, Nathan C. Gianneschi*
J. Am. Chem. Soc., 2014, 136 (43), 15422–15437, DOI: 10.1021/ja5088216z
 

Carrie R. James, Anthony M. Rush, Thomas Insley, Lela Vuković, Lisa Adamiak, Petr Král, Nathan C. Gianneschi* J. Am. Chem. Soc., 2014, 136 (32), 11216–11219, DOI: 10.1021/ja503142s

 

Anthony M. Rush, David A. Nelles, Angela P. Blum, Sarah A. Barnhill, Erick T. Tatro, Gene W. Yeo, Nathan C. Gianneschi*
J. Am. Chem. Soc., 2014, 136 (21), 7615–7618, DOI: 10.1021/ja503598z

 

Maria T. Proetto, Anthony M. Rush, Miao-Ping Chien, Patricia Abellan Baeza, Joe P. Patterson, Matthew P. Thompson, Norman H. Olson, Curtis E. Moore, Arnold L. Rheingold, Christopher Andolina, Jill Millstone, Stephen B. Howell, Nigel D. Browning, James E. Evans, and Nathan C. Gianneschi 
J. Am. Chem. Soc., 2014, 136 (4), 1162-1165, DOI: 10.1021/ja408513m

 

Matthew P. Thompson, Lyndsay M. Randolph, Carrie R. James, Ashley N. Davalos, Michael E. Hahn, and Nathan C. Gianneschi
Poly. Chem., 2014, 5, 1954-1964, DOI: 10.1039/C3PY01338C

 

Yu-Ru V. Shih, YongSung Huang, Ameya Phadke, Heemin Kang, Nathaniel S. Hwang, Eduardo Caro, Steven Nguyen, Michael Siu, Emmanuel A. Theodorakis, Nathan C. Gianneschi, Kenneth S. Vecchio, Shu Chien, Oscar K. Lee, and Shyni Varghese
PNAS, 2013, DOI: 10.1073/pnas.1321717111

 

Nuclease-Resistant DNA via High-Density Packing in Polymeric Micellar Nanoparticle Corona
 

Anthony M. Rush, Matthew P. Thompson, Erick T. Tatro, Nathan Gianneschi*, ACSNano2013DOI: 10.1039/C2SC20165H

 

Miao-Ping Chien, Andrea S. Carlini, Dehong Hu, Christopher V. Barback, Anthony M. Rush, David J. Hall, Galya Orr, and Nathan C. Gianneschi
J. Am. Chem. Soc., 2013, 135 (50), 18710-18713, DOI: 10.1021/ja408182p

 

Miao-Ping Chien, Matthew P. Thompson, Christopher V. Barback, David J. Hall, and Nathan C. Gianneschi* Adv. Mat., 2013, 25 3599-3604, DOI: 10.1002/adma.201300823

 

Jacquelin K. Kammeyer, Angela P. Blum, Lisa Adamiak, Michael E. Hahn, and Nathan C. Gianneschi* Poly. Chem., 2013, 4, 3929-3933, DOI: 10.1039/C3PY00526G

 

Michael E. Hahn, Lyndsay M. Randolph, Lisa Adamiak, Matthew P. Thompson and Nathan C. Gianneschi
Chem. Comm., 2013, 49, 2873-2875, DOI: 10.1039/C3CC40472B

 

Miao-Ping Chien, Matthew P. Thompson, Eugene C. Lin and Nathan C. Gianneschi* Chem. Sci., 2012, 3, 2690-2694, DOI: 10.1039/C2SC20165H

 

Lyndsay M. Randolph, Miao-Ping Chien and Nathan C. Gianneschi* Chem. Sci., 2012, 3, 1363-1380, DOI: 10.1039/C2SC00857B

 

Michael E. Hahn and Nathan C. Gianneschi Chem. Comm., 2011, 47, 11814-11821, DOI: 10.1039/C1CC15220C

 

Joseph M. Kinsella, Rebecca E. Jimenez, Priya P. Karmali, Anthony M. Rush, V. Ramana Kotamraju, Nathan C. Gianneschi, Erkki Ruoslahti, Dwayne Stupack, Michael J. Sailor Angew. Chem. Int. Ed., 2011, 50, 12308-12311, DOI: 10.1002/anie.201104507

 

Joseph M. Kinsella, Shalini Ananda, Jennifer S. Andrew, Joel F. Grondek, Miao-Ping Chien, Miriam Scadeng, Nathan C. Gianneschi, Erkki Ruoslahti, Michael J. Sailor Adv. Mat., 2011, 23, H248-H253, DOI: 10.1002/adma.201101877

 

Miao-Ping Chien and Nathan C. Gianneschi Small, 2011, 7, 2041-2046, DOI: 10.1002/smll.201101014

 

Ti-Hsuan Ku, Miao-Ping Chien, Matthew P. Thompson, Robert S. Sinkovits, Norman H. Olson, Timothy S. Baker, and Nathan C. Gianneschi* J. Am. Chem. Soc., 2011, 133 (22), 8392-8395, DOI: 10.1021/ja2004736

 

Miao-Ping Chien, Matthew P. Thompson, and Nathan C. Gianneschi* Chem. Comm., 2011, 47, 167-169, DOI: 10.1039/C0CC02291H

 

Mark Rubinshtein, Carrie R. James, Jennifer L. Young, Yanyan J. Ma, Yoshihisa Kobayashi, Nathan C. Gianneschi, and Jerry, Yang
Org. Lett., 2010, 12 (15), 3560-3563, DOI: 10.1021/ol101433v

 

Matthew P. Thompson, Miao-Ping Chien, Ti-Hsuan Ku, Anthony M. Rush, and Nathan C. Gianneschi* Nano Lett., 2010, 10 (7), 2690-2693, DOI: 10.1021/nl101640k

 

Miao-Ping Chien, Anthony M. Rush, Matthew P. Thompson, and Nathan C. Gianneschi
Angew. Chem. Int. Ed., 2010, 49, 5076-5080, DOI: 10.1002/anie.201000265

 

Selected Publications – Northwestern University, The Scripps Research Institute

 

Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme
Nathan C. Gianneschi, and M. Reza Ghadiri ANGEWANDTE CHEMIE-INTERNATIONAL EDITION200746, 3955-3958

Development of a coordination chemistry-based approach for functional supramolecular structures
Nathan C. Gianneschi, Martin S. Masar III, and Chad A. Mirkin ACCOUNTS OF CHEMICAL RESEARCH200538, 825-837

Signal amplification and detection via a supramolecular allosteric catalyst
Nathan C. Gianneschi, SonBinh T. Nguyen, and Chad A. Mirkin JOURNAL OF THE AMERICAN CHEMICAL SOCIETY2005127, 1644-1645

Reversibly addressing an allosteric catalyst in situ: catalytic molecular tweezers
Nathan C. Gianneschi, SonBinh T. Nguyen, and Chad A. Mirkin ANGEWANDTE CHEMIE-INTERNATIONAL EDITION200443,5503-5507

A supramolecular approach to an allosteric catalyst 
Nathan C. Gianneschi, Paul A. Bertin, SonBinh T. Nguyen, Chad A Mirkin, Lev N Zakharov, and Arnold L. Rheingold JOURNAL OF THE AMERICAN CHEMICAL SOCIETY2003125, 10508-10509