Department of Molecular Biosciences
Mechanism and regulation of mithocondrial positioning
We are interested in the fundamental question of how mitochondria are positioned in cells. Central to mitochondrial positioning are molecular tethers that function to anchor mitochondria to specific cellular sites. Using multidisciplinary biochemical, cytological and genetic approaches that take advantage of the facile yeast system, we are working to elucidate the molecular mechanism, regulation and physiological significance of mitochondrial tethering.