Team

The Carvill lab is made up of a team of geneticists, molecular and computational biologists. Read more about our team members below.

We also collaborate closely with clinicians and clinical staff at the Comprehensive Epilepsy Center at Northwestern Memorial Hospital and pediatric neurology at Lurie Children’s Hospital.

Principal Investigator

Gemma L. Carvill, PhD (she/her)

Gemma L. Carvill, PhD (she/her)

Primary Investigator

Animal form – panda

Email

Assistant Professor of Neurology – Ken and Ruth Davee Department and Pharmacology

Departments of Pharmacology and Pediatrics (secondary)

Gemma Carvill is an Assistant Professor in the Department of Neurology at Northwestern University Feinberg School of Medicine in Chicago, IL. She received her Bachelor of Science from the University of Pretoria and her PhD in Human Genetics from the University of Cape Town in South Africa. Dr. Carvill performed her postdoctoral work in the laboratory of Dr. Heather Mefford at the University of Washington where she used genomic sequencing approaches to identify novel genetic etiologies in the pediatric epilepsies. Her lab at Northwestern continues to use these technologies to define the molecular basis of epilepsy and provide answers for patients and families. Her group also uses patient-derived stem cell models to study how mutations in genes involved in epigenetic mechanisms cause epilepsy. Gemma is a recipient of a NIH Pathway to Independence Award in 2014 and the NIH Innovator’s award in 2018. Her independent research was made possible by early career awards from Citizens United for Research in Epilepsy (CURE), the American Epilepsy Society (AES) and most recently, the Dravet Syndrome Foundation. At Northwestern, Dr. Carvill interfaces with the adult and pediatric clinical teams to expand neurogenetics research and to facilitate genetic diagnoses for more patients and families affected by epilepsy.

Lab Members

Meet the Carvill Lab team members. We welcome requests for information about our work and collaboration opportunities!

Jeff Calhoun, PhD (he/him)

Jeff Calhoun, PhD (he/him)

Research Assistant Professor

Animal form – dolphin

Email

Jeff received a PhD in Cellular and Molecular Biology at the University of Michigan in 2013 under the mentorship of Dr. Lori Isom. For his postdoctoral training, he studied the genetics of epilepsy in mice and humans in the laboratories of Dr. Jennifer Kearney and Dr. Gemma Carvill. His research interests focus on improving the genetic diagnosis of epilepsy through genome sequencing, machine learning, and functional characterization of variants of uncertain significance. Outside of the laboratory, Jeff enjoys volleyball and racquetball (when his knees cooperate) and attempting to reproduce recipes from the internet (with occasional success).

Sheng Tang, MD PhD (he/him)

Sheng Tang, MD PhD (he/him)

Postdoctoral Fellow

Animal form – wolf

Email

Sheng is a postdoctoral fellow who is interested in studying the genetic and epigenetic underpinnings of epilepsy. He received his MD and PhD from the University of Pennsylvania, where he studied the neural circuit mechanisms of CDKL5 deficiency disorder, a developmental and epileptic encephalopathy. Here at Northwestern, he is completing the adult neurology residency and plans to specialize in epilepsy. His current project focuses on novel noncoding variants in SCN1A that lead to Dravet syndrome. In his free time, he enjoys running, playing badminton, and baking treats for friends and family.

Jennifer Cheng (she/her)

Jennifer Cheng (she/her)

DGP PhD Student

Animal form – cat
 
 

Jennifer is a graduate student in the DGP. She graduated from the University of Illinois at Urbana-Champaign in 2018 with a BS in Biochemistry and double minors in Business and Chemistry. Throughout her undergraduate degree, she was fortunate enough to contribute to multiple areas of research, including polyphosphate as a modulator of hemostasis, optogenetic manipulation and study of Wnt signaling, and solute carrier protein crystallography. Her work in Dr. Carvill’s lab focuses on elucidating the role of CUX2 dysfunction in the pathology of developmental and epileptic encephalopathies. In her free time, Jennifer enjoys golfing, playing the piano, and updating her food Instagram (@jzchengeats) with her latest cooking and dining explorations.

 
Aishwarya Ramamurthy (she/her)

Aishwarya Ramamurthy (she/her)

DGP PhD Student

Animal form – giraffe 

Email

Aishwarya graduated from Purdue School of Science, IUPUI in 2014 with an MS degree, where her research focused on biochemical characterization of proteasomal assembly intermediates. She then joined Dr. Steve Kron’s lab at University of Chicago where she studied DNA repair mechanisms in the context of cancer metabolism. As an undergrad, she worked in national research institutes in India where her varied projects involved investigating chaperone functions of human small heat shock proteins (sHsps), establishing a genome database for neem trees (A. Indica) and studying genetic variants in Hirschsprung’s disease. Currently in the Carvill lab, Aishwarya is investigating the role of chromatin organization to understand pathogenic mechanisms that underpin genetic epilepsies. When not in lab, you can find her hanging out by the lake, or exploring Chicago’s visual art, music and food scene.

Mia Broad (she/her)

Mia Broad (she/her)

DGP PhD Student

Animal form – dog

Email 

Mia is a graduate student in the DGP. She first started pursuing academic research at the Buck Institutes for Research on Aging in Novato, CA in the lab of Dr. Dale Bredesen, studying BACE-1 cleavage of amyloid precursor protein (APP). She then worked at Dr. Varghese John’s lab at UCLA and studied a range of neurodegenerative disorders from Alzheimer’s disease to multiple sclerosis. After graduating from UCLA in 2018 with a B.S. in Neuroscience, she worked as a research associate in Dr. Robert Mahley’s lab at the Gladstone Insititutes at UCSF studying the strongest genetic risk factor for Alzheimer’s disease, APOE. Now, she is pursuing her thesis research at the Carvill lab and is studying poison exons and their effect on neurodevelopment and epileptic disorders as a computational biologist. In her free time, she enjoys playing tennis, cooking, baking, listening to live music, and going to the beach.

Esther Yoon (she/her)

Esther Yoon (she/her)

MD/PhD Student

Animal form – quokka

Email

Esther is a MD/PhD student at Northwestern University Feinberg School of Medicine. She received her Bachelor of Science in neuroscience with minors in biology, psychology, and music from Indiana University. Her undergraduate thesis focused on the neural correlates of executive functions in EEG in toddlers. She then joined the NIH Human Motor Control Section to investigate the phenotype-genotype relationship of Parkinson’s disease using genetics, neuroimaging, and clinical data. Her interest in genetics and neurology led her to the Carvill lab, where she currently probes the role of CHD2 abundance and deficiency in neurodevelopmental disorders. Outside the lab, Esther likes to spend her time reading, playing music, running along the lakeshore, and hanging out with her friends and family.

Nico Bodkin (he/him)

Nico Bodkin (he/him)

MD/PhD Student

Animal form – mouse

Email 

Nico is an MD/PhD student at Northwestern interested in the intersection of functional genomics and computational biology. He graduated from Duke University in 2020, where he received a BS in Biology, BA in Computer Science, and a minor in Chemistry. After graduating, he spent a year at Octant where he developed tools to scale up their drug discovery platform. In the Carvill Lab, Nico is excited to apply his experience in high-throughput assays to the fields of neurogenetics and variant resolution. Outside of lab, Nico enjoys exploring Chicago’s neighborhoods, trying out new restaurants and cafés, and overspending on plants for his home.

Joe Minton (they/them)

Joe Minton (they/them)

NUIN PhD Student

Animal form – otter

Email 

Joe is a graduate student in NUIN. Joe received a BS in psychology from the University of Massachusetts, Amherst. Joe then received a MS in
pharmacology at the University of Michigan. Under the mentorship of Dr.
Lori Isom, Joe studied Sex as a Biological Variable in mouse models of
genetic epilepsies, as well as splicing of voltage-gated sodium channel
subunits. Currently, in the Carvill Lab, Joe is investigating the functional
roles CHD2 has in neurodevelopment. Outside of lab, Joe enjoys live music,
going to the beach, dinner parties with friends, antiquing, and reality tv.

Mash Bandouil (they/them)

Mash Bandouil (they/them)

Research Technologist III

Animal form – alpaca

Email 

Mash is a graduate from Loyola University of Chicago with a BS in Biology and a BA in Dance. In the lab of Dr. Jennifer Mierisch, Mash researched gene conservation in the Insulin signaling pathway. They then spent 2 years as a Research Technologist in the Carvill lab analyzing the genetic causes of epilepsy – namely, the impact of CHD2 on neuronal development in cerebral organoids. Afterwards, Mash spent a year in the Biological Modeling Laboratory at Tempus AI generating organoids from human tumor samples to be used in various cancer drug assays. Mash is so happy to be back in the Carvill lab where they will continue their work with 3D cell models as well as various gene editing projects. Outside of lab, Mash is a professional dancer and has a passion for using dance to make science more accessible. They create dance films (many with graduate student Jennifer Cheng!) that have been showcased at benefit concerts, science communication conferences, and the international Dance your PhD competition. 

Ojasi Joshi (she/her)

Ojasi Joshi (she/her)

Research Technologist II

Animal form – deer

Email 

Ojasi completed her undergraduate degree in Pharmacy in India. She moved to US and graduated from University at Buffalo, SUNY in 2024 with an MS degree in Pharmacology and Toxicology, where her research focused on investigating the localization of various membrane proteins to the large dense core vesicles of the human dorsal root ganglion neurons. Currently, in the Carvill Lab, as a Research Tech, she is having fun exploring the world of Epilepsy while collaborating and learning new techniques and approaches to find cure. Outside the lab, Ojasi loves singing, dancing, listening to music, occasional baking and going on long drives!

Maggie Johnson (she/her)

Maggie Johnson (she/her)

Undergraduate

Animal form – gazelle

Email 

My name is Maggie Johnson and I am an undergraduate student at Northwestern majoring in Biological Sciences with a concentration in Human Health and Disease, with a minor in data science and a minor in cognitive science. Outside of the Carvill lab, I enjoy participating in both the Northwestern club swim team and club water polo team, as well as serving as the chapter co-president of the Northwestern chapter of NMDP (National Marrow Donor Program). In my free time, I enjoy spending time with friends and family, finding cool dinner spots in Chicago, and spending time at the beach (when it’s warm :)).

Adult Epilepsy Genetics Team

This program is co-directed by Dr. Elizabeth Gerard (left), a clinical epileptologist, and Dr. Carvill (center-right) along with Senior Genetic Counselor, Lisa Kinsley (MS, CGC) (right) and clinical research associate support from Irena Bellinski(center-left). Dr. Gerard and Lisa Kinsley see patients clinically with suspected genetic causes of epilepsy, and we recruit interested patients and families in research studies to find genetic causes of epilepsy as well as study these variants in cellular models.

Alumni 

Carina Briar, Research Technologist I, now PhD student at University of Washington

Cole Pfeifer, Research Technologist I

Likhita Aluru, Undergraduate

Karthik Sathish, Undergraduate

Julia Schnipper, Undergraduate

Lauren Petreanu, DGP PhD Student

Masha Bandouil, Research Technologist II, now Research Associate II at Tempus Labs, Inc.

Hannah Happ, DGP PhD Student, now Postdoc at University of Utah

Haritha Potineni, Research Technologist II

Jung HongResearch Technologist III, now on 2 year Japan adventure

Kay Marie-LamarPostdoc, now AAAS Science and Technology Policy Fellow

Eleanor Goes, Undergraduate

Patricia Schneider, Postdoc, now Assistant Professor at LSU

Jonathan Gunti, Bioinformatician, now Senior Bioinformatics Software Developer at the National Institute of Health

Mimi Aziz, Research Technologist II, now PhD student at University of Utah

Marta Amador, Undergraduate, now PhD Student at University of Edinburgh

Aishwarya Ramamurthy, Research Technologist II, now DGP PhD student at Northwestern University

Michele Arnoldi, Visiting Research Scientist, now PhD student at The University of Trento, Italy

MC Schultz, Research Technologist II, now PhD student at the University of Chicago

Mattina Alonge, Research Technologist II, now PhD student at UC Berkley

Kristy Zheng, Undergraduate, now medical student at Feinberg School of Medicine

Chris Miller, Research Technologist II

Katherine Anjali Fleck, Summer Undergraduate Student