Publications

Brickner, D.G, C. Randise-Hinchliff, M. L. Corbin, J. M. Liang, S. Kim, B. Sump, A. D’Urso, S. H. Kim, A. Satomura, H. Schmit, R. Coukos, S. Hwang, R. Watson & J. H. Brickner (2019).  The role of transcription factors and nuclear pore proteins in controlling the spatial organization of the yeast genomeDevelopmental Cell 49: 936-947.

Randise-Hinchliff, C. and Brickner, J.H. (2018). Nuclear pore complexes in genome organization and gene expression in yeast. In Nuclear Pore Complexes in Genome Organization, Function and Maintenance.  Maximilliano D’Angelo, editor, Springer International Publishing AG.

Sump, B. and Brickner, J.H. (2017). Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis.  Genes & Development, 31: 2201-2203.

Sood, V. and J.H. Brickner (2017).  Genetic and epigenetic strategies potentiate Gal4 activation to enhance fitness in recently diverged yeasts.  Curr. Biol. 27: 3591-3602.

Satomura, A. & Brickner, J.H. (2017). The Nuclear Pore Complex as a nexus of regulation of developmental gene expressionTrends Cell Biol. 27: 621-622.

Varun Sood, Ivelisse Cajigas, Agustina D’Urso, William H. Light and Jason H. Brickner (2017). Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae.  Genetics 206 (4): 1895-1907.

Kim, S., Liachko, I., Brickner, D.G, Cook, K.,Noble, W.S., Brickner, J.H., Shendure, J., Dunham, M. J. (2017). The dynamic three-dimensional organization of the diploid yeast genome. eLife.

D’Urso, A. & Brickner, J.H. (2017). Memory is the treasury and guardian of all things.  Mol. Cell 66:5-6.

Brickner, J.H. (2017).  Genetic and epigenetic control of the spatial organization of the genome. Mol. Biol. Cell 28 (3): 364-369. 

D’Urso, A. & Brickner, J.H. (2016).  Epigenetic Transcriptional Memory. Curr Genet (2016). doi:10.1007/s00294-016-0661-8

Brickner, D.G., V. Sood, E. Tutucci, R. Coukos, K. Viets, R. Singer and J.H. Brickner (2016). Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms. Mol. Biol. Cell, 27: 2980-2993.

Randise-Hinchliff, C., and J. H. Brickner (2016). Transcription factors dynamically control the spatial organization of the yeast genome. Nucleus DOI:10.1080/19491034.2016.1212797

D’Urso, A., Y. Takahashi, B. Xiong, J. Marone, R. Coukos, C. Randise-Hinchliff, J.-P. Wang, A. Shilatifard and J.H. Brickner (2016).  Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory.  eLife 2016; 10.7554/eLife.16691

Randise-Hinchliff, C., R. Coukos, V. Sood, M. C. Sumner, S. Zdraljevic, L. Meldi Sholl, D.G. Brickner, S. Ahmed, L. Watchmaker and J.H. Brickner (2016). Strategies to regulate transcription factor-mediated gene positioning and interchromosomal clustering at the nuclear periphery. J. Cell Biol. 212(6): doi:10.1083/jcb.201508068.

Brickner, D.G., Coukos, R., and Brickner, J.H. (2015). INO1 transcriptional memory leads to DNA zip code dependent interchromosomal clustering. Microbial Cell. 2(12): 481-490.

Egecioglu, D.E., A. D’Urso, D.G. Brickner, W.H. Light and J. H. Brickner (2014). Approaches to studying subnuclear organization and gene-nuclear pore interactions.  In Methods in Cell Biology, Nuclear pore complex and nucleocytoplasmic transport.  Valerie Doye, editor, 122: 463-485. PMCID: PMC2857743

D’Urso, A. and Brickner, J.H. (2014). Mechanisms of epigenetic memory. Trends Gen. 30(6), 230-236.

Sood, V. and Brickner, J.H. (2014). Nuclear pore interactions with the genome. Curr. Opin. Gen. Dev.25: 43-49.

Light, W.H. and Brickner, J.H. (2013). Nuclear pore proteins regulate chromatin structure and transcriptional memory by a conserved mechanism. Nucleus 4(5), 1-4.

Gaur, N.A., J. Hasek, D.G. Brickner, H. Qiu, F. Zhang, C.-M. Wong, I. Malcova, P. Vasicova, J.H. Brickner and A. Hinnebusch (2013). Vps factors are required for efficient transcription elongation in budding yeast. Genetics 193(3): 829-51.

Light, W.H., FreaneyJ., Sood V., Thompson A., D’Urso A., et al.(2013). A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. PLoS Biol. 11(3): e1001524.

Brickner, D.G. and Brickner, J.H. (2012). Interchromosomal clustering of active genes at the nuclear pore complex. Nucleus 3:6 1-6.

Randise-Hinchliff, C.E. and Brickner, J.H. (2012). A new direction for gene looping. Dev. Cell 23: 919-921.

Brickner, D.G., S. Ahmed, L. Meldi, A. Thompson, W. Light, M. Young, T.L. Hickman, F. Chu, E. Fabre and J.H. Brickner. (2012). Transcription factor binding to a DNA zip code controls interchromosomal clustering at the nuclear periphery. Dev. Cell 22, 1-13.

Brickner, J.H. (2011). Nuclear architecture- the cell biology of a laminopathy. Curr. Biol. 21: R807-809.

Meldi, L. and J.H. Brickner (2011). Compartmentalization of the nucleus. Trends Cell Biol. 21(12): 701-8.

Leung, A. I. Cajigas, P. Jia, E. Ezhkova, J. H. Brickner, Z. Zhao, F. Geng, and W. Tansey (2011). Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat. Mol. Biol. Cell. 22: 2741-2753.

Egecioglu, D. and J.H. Brickner (2011). Gene positioning and expression. Curr. Opin. Cell Biol. 23: 338-345.

D. G. Brickner & J.H. Brickner (2011). Gene positioning is regulated by phosphorylation of the nuclear pore complex by Cdk1. Cell Cycle 10(3): 1-4.

Brickner, D.G., W.Light and J.H. Brickner (2010). Quantitative localization of chromosomal loci by immunofluorescence. Meth. Enzymol. 470: 571-582.

Light, W., D. G. Brickner, V. Brand and J.H. Brickner (2010). Interaction of a DNA zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol. Cell 40: 112-125.

Brickner, D.G. and J.H. Brickner (2010). Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle. Mol. Biol. Cell 21: 3421-3432.

Ahmed, S. and J.H. Brickner (2010). A role for DNA sequence in controlling the spatial organization of the genome.  Nucleus. 1 (5): 1-5.

Ahmed, S., D.G. Brickner, W.H. Light, I. Cajigas, M. McDonough, A.B.Froyshteter, T. Volpe., and J.H. Brickner (2010). DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery. Nat Cell Biol. 12 (2): 111-118.

Brickner, J.H. (2010). Transcriptional memory- staying in the loopCurr. Biol. 20(1): R20-R21.

Gard, S., W. Light, B. Xiong, T. Bose, A.J. McNairn, B. Harris, B. Fleharty, C. Seidel, J.H. Brickner and J.L. Gerton (2009). Cohesinopathy mutations disrupt the subnuclear organization of chromatin. J Cell Biol. 187(4): 455–462.

Brickner, J.H. (2009). Transcriptional memory at the nuclear periphery. Curr. Opin. Cell Biol. 21:1-7.

Ahmed, S. and J.H. Brickner (2007). Regulation and epigenetic control of transcription at the nuclear periphery. Trends in Genetics.

Brickner, D.G.,I. Cajigas, Y. Fondufe-Mittendorf, S. Ahmed, P.-C. Lee, J. Widom and J.H. Brickner(2007). H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS 5(4): e81.

Brickner, J.H. and P. Walter (2004). Gene recruitment of the activated INO1 locus to the nuclear membranePLoS Biol 2(11): e342.