Publications – Min Laboratory

Kim, D., G. Kim, R. Yu, J. Lee, S. Kim, M.R. Gleason, K. Qiu, E. Montauti, L.L. Wang, D. Fang, J. Choi, N.S. Chandel, S. Weinberg, B. Min. Inhibitory coreceptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming. Immunity 10.1016/j.immuni.2024.08.008

Iamwasat, S., R. Yu, S. Kim, N. Dvorina, K. Qiu, J. Choi, W.M. Baldwin III, B. Min. Single cell analysis uncovers striking cellular heterogeneity of lung infiltrating Tregs during eosinophilic vs. neutrophilic allergic airway inflammation. J. Immunol. 212:1867-1876. doi.org/10.4049/jimmunol.2300646
Martinez GJ, Appleton M, Kipp ZA, Loria AS, Min B, Hinds TD Jr. Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries. 2024. Physiol Rev. Jan 1;104(1):473-532. doi: 10.1152/physrev.00021.2023.

Vasquez Ayala A, Hsu CY, Oles RE, Matsuo K, Loomis LR, Buzun E, Carrillo Terrazas M, Gerner RR, Lu HH, Kim S, Zhang Z, Park JH, Rivaud P, Thomson M, Lu LF, Min B, Chu H. Commensal bacteria promote type I interferon signaling to maintain immune tolerance in mice. 2024 J Exp Med. Jan 1;221(1):e20230063. doi: 10.1084/jem.20230063.

Kim, D., S. Kim, M-s. Kang, Z. Yin, and B, Min. (2023). Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation. Scientific Reports. 2023 Feb 1;13(1):1812. doi: 10.1038/s41598-023-27413-w.
Kim, D., N. K. Rai, A. Burrows, S. Kim, A. Tripathi, S.E. Weinberg, R. Dutta, G.C. Sen, and B. Min. (2023). IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity. J. Immunol. 2023 Mar 15;210(6):721-731. doi: 10.4049/jimmunol.2200746.

Kohei, N., T. Tanaka, S. Miyairi, H. Tsuda, T. Abe, C.A. Su, D.D. Kish, K. Tanabe, A. Valujskikh, B. Min, and R.L. Fairchild. (2023). Failure of costimulatory blockade-induced Tregs to sustain long-term survival of high ischemic allografts. Transplantation. In Press.

Fink, E.E., S. Sona, U. Tran, P-E. Desprez, M. Bradley, H. Qiu, M. Eltemamy, A. Wee, M. Wolkov, M. Nicolas, B. Min, G-P. Haber, O. Wessely, B.H. Lee, and A.H. Ting. (2022). Single-cell and spatial mapping identify cell types and signaling networks in the human ureter. Developmental Cell 57:P1899-1916.
Lee, J., D. Kim, and B. Min. (2022). Tissue resident Foxp3⁺ regulatory T (TR-Treg) cells: sentinels and saboteurs in health and disease. Front. Immunol. 13:865593.
Pratumchai, I., J. Zak, Z. Huang, B. Min, M.B.A. Oldstone, and J.R. Teijaro. (2022). B cell-derived IL-27 promotes control of persistent LCMV infection. Proc. Natl. Acad. Sci. USA 119:e2116741119.2022

Lin, C-H., M-C. Chen, L-L. Lin, D. Christian, B. Min, C. Hunter, and L-F. Lu. (2021). Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes. J. Exp. Med. 218(11):e20210021. DOI: 10.1084/jem.20210021. PMCID: PMC8480671
Nguyen, Q.T., D. Kim, S. Iamsawat, H.T. Le, S. Kim, K.T. Qiu, T.D. Hinds, P. Bazeley, J.J. O’Shea, J. Choi, K. Asosingh, S.C. Erzurum, and B. Min. (2021). Cutting Edge: Steroid responsiveness in Foxp3+ regulatory T cells determines steroid sensitivity during allergic airway inflammation in mice. J. Immunol. 207:765-770. DOI: 10.4049/jimmunol.2100251 PMCID:PMC7212959
Min, B., D. Kim, and M.J. Feige. (2021). IL-30 (IL-27A): a familiar stranger in immunity, inflammation, and cancer. Experimental & Molecular Medicine. 53:823-834. DOI: 10.1038/s12276-021-00630-x. PMCID:PMC8178335

Evonuk, K.S., R.E. Doyle, C.E. Moseley, I.M. Thornell, K. Adler, A.M. Bingaman, M.O. Bevensee, C.T. Weaver, B. Min, and T.M. DeSilva. (2020). Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci. Adv. 6:eaax5936.
https://doi.org/10.1126/sciadv.aax5936

PMID: 31934627
Le, H.T., K. Kaslar, Q.T. Nguyen, B.R. Blazar, B.K. Hamilton, and B. Min. (2020). Interleukin-27 enforces regulatory T cell functions to prevent graft versus host diseases. Front. Immunol. 11:181.
https://doi.org/10.3389/fimmu.2020.00181

PMID: 32117306
Kim, D., Q.T. Nguyen, J. Lee, S.H. Lee, S. Kim, K. Kaslar, N. Dvorina, K. Weiss, K. Asosingh, S.C. Erzurum, W.M. Baldwin, J-S. Lee, and B. Min. (2020). Anti-inflammatory roles of glucocorticoids are mediated by Foxp3+ regulatory T cells via a miR-342-dependent mechanism. Immunityhttps://doi.org/10.1016/j.immuni.2020.07.002. PMID: 32707034

Nguyen, Q.T., E. Jang, H. Le Thi, S. Kim, S. Comhair, S.C. Erzurum, and B. Min. (2019) IL-27 targets Foxp3+ Tregs to mediate antiinflammatory functions during experimental allergic airway inflammation. JCI Insight 4(2):e123216.
https://doi.org/10.1172/jci.insight.123216

PMID: 30674714
Kim, D., Q.T. Nguyen, S. Kim, J. Lee, and B. Min. (2019). Cutting Edge: IL-27 attenuates autoimmune neuroinflammation via Treg/Lag3-dependent but IL-10-independent mechanisms in vivo. J. Immunol. 202:1680-1685.
https://doi.org/10.4049/jimmunol.1800898

PMID: 30700587
He, Y., J. Shi, Q.T. Nguyen, E. You, H. Liu, X. Ren, J. Li, W. Qiu, S.K. Khoo, T. Yang, W. Yi, X. Huang, K. Melcher, B. Min*, and H.E. Xu*. (2019). Development of novel highly potent glucocorticoids for steroid-resistant severe asthma. Proc. Natl. Acad. Sci. USA 116:6932-6937. *Co-corresponding author
https://doi.org/10.1073/pnas.1816734116

PMID: 30894497
Ayasoufi, K., D.B. Zwick, R. Fan, S. Hasgur, V. Gorbacheva, K.S. Keslar, B. Min, R.L. Fairchild, and A. Valujskikh. (2019). Interleukin-27 promotes CD8 T cell reconstitution following antibody-mediated lymphoablation. JCI Insight. 4(7):e125489.
https://doi.org/10.1172/jci.insight.125489

Tsuda, H., C. Su, T. Tanaka, K. Ayasoufi, B. Min, A. Valujskikh, and R. Fairchild. (2018). Allograft dendritic cell p40 homodimers activate donor-reactive memory CD8 T cells. JCI Insight. 3:e96940.
Min B. (2018). Spontaneous T cell proliferation: A physiologic process to create and maintain homeostatic balance and diversity of the immune system. Front. Immunol. 9:547.
https://doi.org/10.3389/fimmu.2018.00547

Do J-S, Kim S, Keslar K, Jang E, Huang E, Fairchild RL, Pizarro TT, Min B. γδ T cells coexpressing gut homing α4β7 and αE integrins define a novel subset promoting intestinal inflammation. (2017) J. Immunol. 198:908-915.
https://doi.org/10.4049/jimmunol.1601060

PMID: 27927968
Min B. Heterogeneity and Stability in Foxp3+ Regulatory T Cells. (2017) J. Interferon Cytokine Res. 37:386-397.
https://doi.org/10.1089/jir.2017.0027

PMID: 28696819
Do J, Kim D, Kim S, Valentin-Torres A, Dvorina N, Jang E, Nagarajavel V, DeSilva TM, Li X, Ting AH, Vignali DAA, Stohlman SA, Baldwin WM, Min BTreg specific IL-27Ra deletion uncovers a key role for IL-27 in Treg functions to control autoimmunity independent of IL-10⁺ Tr1 cells. (2017) Proc. Natl. Acad. Sci. USA 114:10190-10195.
https://doi.org/10.1073/pnas.1703100114

PMID: 28874534
Jang E, Nguyen QT, Kim S, Kim D, Le THN, Keslar K, Dvorina N, Aronica MA, Min B. Lung infiltrating Foxp3⁺ regulatory T cells are quantitatively and qualitatively different during eosinophilic and neutrophilic allergic airway inflammation but essential to control the inflammation. (2017) J. Immunol. 199:3943-3951.
https://doi.org/10.4049/jimmunol.1700211

PMID: 29093062