Publications

See all publications by Dr. Bass on PubMed

PEER-REVIEWED ARTICLES:

Rizzini, L, Levine, DC, Perelis, M, Bass, J, Peek, CB, Pagano, M. 2019. Cryptochromes-mediated Inhibition of the CRL4^Cop1_Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism. Current Biology 29, 1–9.

Cedernaes, J, Huang, W, Ramsey, KM, Waldeck, N, Cheng, L, Marcheva, B, Omura, C, Kobayashi, Y, Peek, CB, Levine, DC, Dhir, R, Awatramani, R, Bradfield, CA, Wang, XA, Takahashi, JS, Mokadem, M, Ahima, RS, Bass, J. 2019.Transcriptional basis for rhythmic control of hunger and metabolism within the AgRP neuron,Cell Metab. 2019 Feb 18. pii: S1550-4131(19)30063-4. doi: 10.1016/j.cmet.2019.01.023. [Epub ahead of print]

• • • • *This paper hasbeen profiled in the following editorials:
      • Starling, S. 2019. Neuronal clock coordinates appetite. Nat Rev Endocrinol.2019 May;15(5):253. doi: 10.1038/s41574-019-0196-4.
      • Zheng, C. 2019. Temporal Control of Appetite by AgRP Clocks. Cell Metab.2019 May 7;29(5):1022-1023. doi: 10.1016/j.cmet.2019.04.009

Hong, HK, Maury, E, Ramsey, KM, Perelis, M, Marcheva, B, Omura, C, Kobayashi, Y, Guttridge, DC, Barish, GD, Bass, J. 2018. Requirement for NF-kB in Maintenance of Molecular and Behavioral Circadian Rhythms in Mice. Genes Dev.32(21-22):1367–1379.Published in Advance October 26, 2018, doi:10.1101/gad.319228.118

• • • • *This paper hasbeen profiled in the following editorials:
      • Gachon, F, Yeung, J, Naef, F. 2018. Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock. Genes Dev.32:1359–1360

Peek, CB, Levine, DC, Cedernaes, J, Taguchi, A, Kobayashi, Y, Tsai, SJ, Bonar, NA, McNulty, MR, Ramsey, KM, Bass, J. 2016. Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle. Cell Metab. 2016 Oct 19. pii: S1550-4131(16)30490-9. doi: 10.1016/j.cmet.2016.09.010.

• This paper has been reviewed and profiled in the following editorials:
• Gough, NR. 2017. Daily oxygen rhythms. Sci Signal.2017 Jan 31;10(464). pii: eaam8695. doi: 10.1126/scisignal.aam8695

Perelis, M, Marcheva, B, Ramsey, KM, Schipma, MJ, Hutchison, AL, Taguchi, A, Peek, CB, Hong, HK, Huang, W, Omura, C, Allred, AL, Bradfield, CA, Dinner, AR, Barish, GD, Bass, J. 2015. Pancreatic Beta-Cell Enhancers Regulate Rhythmic Transcription of Genes Controlling Insulin Secretion. Science. 6 November 2015: 350 (6261), aac4250 [DOI:10.1126/science.aac4250]  

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• This paper has been reviewed and profiled in the following editorials:
• Dibner, C, Schibler, U. 2015. Metabolism. A pancreatic clock times insulin release. Science. 2015 Nov 6;350(6261):628-9. doi: 10.1126/science.aad5412.

Schriewer, JM, Peek, CB, Bass, J, Schumacker, PT. 2013. ROS-Mediated PARP Activity Undermines Mitochondrial Function After Permeability Transition Pore Opening During Myocardial Ischemia-Reperfusion. JAHA. 18;2(2):e000159. doi: 10.1161/JAHA.113.000159.

Peek, CB, Affinati, AH, Ramsey, KM, Kuo, SH, Yu, W, Sena, LA, Ilkayeva, O, Marcheva, B, Kobayashi, Y, Omura, C, Levine, DC, Bacsik, DJ, Gius, D, Newgard, CB, Goetzman, E, Chander, NS, Denu, JM, Mrksisch, M, Bass, J. 2013. Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice. Science. 342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19.

• This paper has been reviewed and profiled in the following editorials:
• Muira, G. 2013. A clockwork burn. Nature Chemical Biology 9, 664 (2013) doi:10.1038/nchembio.1371
• Rey, G, Reddy, AB. 2013. Physiology. Rhythmic respiration. Science. 2013 Nov 1;342(6158):570-1. doi: 10.1126/science.1246658.

Shimomura, K, Kumar, V, Koike, N, Kim, TK, Chong, J, Buhr, ED, Whiteley, AR, Low, SS, Omura C, Fenner, D, Owens, JR, Richards, M, Yoo, SH, Hong, HK, Vitaterna, MH, Bass, J, Pletcher, MT, Wiltshire, T, Hogenesch, JB, Lowrey, PL, Takahashi, JS. 2013. Usf1, a Suppressor of the Circadian Clock Mutant Reveals the Nature of the DNA-binding of the CLOCK: BLMAL1 complex. eLIFE. 2013 Apr 9;2:e00426. doi: 10.7554/eLife.00426

Doliba, NM, Fenner, D, Zelent, B, Bass, J, Matschinsky, FM. 2012. Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation. Diabetes Obes Metab. 2012 Oct;14 Suppl 3:109-19. doi: 10.1111/j.1463-1326.2012.01652.x

Horvath, TL, Abizaid, A, Dietrich, MO, Li, Y, Takahashi, JS, Bass, J. 2012. Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center. Molecular Metabolism. 1(2012):79–85 10.1016/j.molmet.2012.08.003 (Epub ahead of print, Aug 2012).  

Jeyaraj, D, Scheer F, Pipperger, JA, Haldar, SM, Lu, Y, Prosdocimo, DA, Eapen, SJ, Cui, Y, Mahabeleshwar, GH, Lee H, Smith, MA, Casadesus, G, Mintz, EM, Sun, H, Wang, Y, Ramsey, KM, Bass, J, Shea, SA, Albrecht, U, Jain, MK. 2012. Klf15 orchestrates circadian nitrogen homeostasis. Cell Metab. Mar 7; 15(3):311-23

Zelent, B, Odili, S, Buettger, C, Zelent, DK, Chen P, Fenner D, Bass J, Stanley C, Laberge M, Vanderkooi JM, Sarabu, R, Grimsby, J, Matschinsky, FM. 2011. Mutational Analysis of Allosteric Activation and Inhibition of Glucokinase. Biochem J. Dec 1;440(2):203-15

Fenner, D, Odili, S, Hong, HK, Kobayashi, Y, Kohsaka, A, Siepka, SM, Vitaterna, MH, Chen P, Zelent, B, Grimsby, J, Takahashi, JS, Matschinsky, FM, Bass, J. 2011. Generation of N-ethyl-N-nitrosourea (ENU) Diabetes Models in the Mouse Demonstrates Genotype-specific Action of Glucokinase Activators. J Biol Chem. Nov 11;286(45):39560-72. Epub 2011 Sep 15.  

Marcheva,B, Ramsey, KM, Buhr, ED, Kobayashi, Y, Su, H, Ko, CH, Ivanova, G, Omura, C, Mo, S, Vitaterna, MH, Lopez, JP, Philipson, LH, Bradfield, CA, Crosby, SA, JeBailey, L, Wang, X, Takahashi, JS, Bass, J. 2010. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. Jul 29;466(7306):571-2. 

• This paper has been reviewed and profiled in the following editorials:
• Lamia, KA, Evans, RM. 2010. Metabolism: Tick, tock, a β-cell clock. Nature 466, 571-572.
• Yoshino, J, Imai, S. 2010. A clock ticks in pancreatic beta cells. Cell Metab. 4;12(2):107-8.

Su, H, Marcheva, B, Meng, S, Liang, FA, Kohsaka, A, Kobayashi, Y, Xu, AW, Bass, J, Wang, X. 2010. Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice. Dev Biol. Mar 1; 339 (1): 38-50 [Epub 2009 Dec 16].

Arble, D, Bass, J, Laposky, AD, Vitaterna, MH, Turek, FW. 2009. Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring). Nov;17(11):2100-2 [Epub 2009 Sep 3].

Chen WS, Peng XD, Wang Y, Xu PZ, Chen ML, Luo Y, Jeon SM, Coleman K, Haschek WM, Bass J, Philipson LH, Hay N. 2009. Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol Cell Biol. Jun;29(11):3151-62 [Epub ahead of print Mar 16]

Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva, B, Hong, HK, Chong, JL, Buhr, ED, Lee, C, Takahashi JS, Imai SI, and Bass J. 2009. Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science. 324(5927):651-4 [Epub ahead of print March 19].

• This paper has been reviewed and profiled in the following editorial:
• Wijnen H. 2009. Circadian rhythms. A circadian loop asSIRTs itself. Science. May 1;324(5927):598-9.

Laposky, AD, Bradley, MA, Williams, DL, Bass, J, Turek, FW. 2008. Sleep-wake regulation is altered in leptin resistant (db/db) genetically obese and diabetic mice. Am J Physiol Regul Integr Comp Physiol. 295(6):R2059-66.

Wu, C, Delano, DL, Mitro, N, Su, SV, Janes, J, McClurg, P, Batalov, S, Welch, GL, Zhang, J, Orth, AP, Walker JR, Glynne, RJ, Cooke, MP, Takahashi, JS, Shimomura, K, Kohsaka, A, Bass, J, Saez, E, Wiltshire, T, Su, AI.  2008.  Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genetics 4(5): e1000070.

Kohsaka, A, Laposky, AD, Ramsey, KM, Estrada, C, Joshu, C, Kobayashi, Y, Turek, FW, Bass, J.  2007. High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab. 6(5):414-421; (featured on journal cover)  

• This paper has been reviewed and profiled in the following editorials:
• Vogel, G. 2007. Tick, Tock: Fat Disrupts the Clock. ScienceNOW. (1106):3
• Ledford, H. 2007. Excessive fat intake can throw out the body clock. Nature. 450(7167):141
• Up all night, eat all day. Dec 14 2007 Leading Edge: Molecular Biology Select. Cell (131):1023.

Ramos, RR, Swanson, A, Bass, J. 2007. Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the ER.  Proc Natl Acad Sci USA. 104(25):10470-10475.

McClurg, P, Janes, J, Wu, C, Delano, DL, Walker, JR, Takahashi, JS, Shimomura, K, Kohsaka, A, Bass, J, Wiltshire, T, and Su, AI. 2007. Genome-wide association analysis in diverse inbred mice: power and population structure. Genetics. 176(1):675-683.

Laposky, AD, Shelton, J, Perrino, N, Bass, J, Dugovic, C, and Turek, FW. 2006. Altered sleep regulation in leptin-deficient mice. Am J Physiol Regul Integr Comp Physiol. 290(4):R894-903.

• This paper has been reviewed and profiled in the following editorial:
• Lydic, R. 2006. Sleep disruption is related to allelic variation in the ob gene. Am J Physiol Regul Integr Comp Physiol. 290(4): R892-893.

Turek, FW, Joshu, C, Kosaka, A, Lin, E, McDearmon, E, Laposky, A, Olson, S, Easton, A, Jensen, D, Eckel, R, Takahashi, J and Bass, J. 2005.  Obesity and metabolic syndrome in Clock mutant mice. Science. 308(5724):1043-1045.  

• This paper has been reviewed and profiled in the following editorials:
• Schwartz, MW. 2005.  Out of synch: Clock mutation causes obesity in mice. Cell Metab. 1(6):355-356.
• Staels, B. 2006. When the Clock stops ticking, metabolic syndrome explodes. Nat Med. 12(1):54-55.
• Wagh, M. 2007. Metabolism gets clocked. The Scientist. 21(4):74.

Reutrakul, S, Hathout, EH, Janner, D, Hara, M, Donfack, J, Bass, J and Refetoff, S. 2004.  Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity and insulin resistance. Thyroid. 14(4):311-319.

Hua, QX, Wilken, J, Nakagawa, S, Ramos, RR, Jia, W, Bass, J and Weiss, MA. 2003. A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.  Genes Dev. 17(7):826-831.

Kim, SH, Wan, R, Gordon, DJ, Bass, J, Steiner, DF, Thinakaran, G, Lynn, DG, Meredith, SC, Sisodia, SS. 2000. Familial British dementia: expression and metabolism of BRI.  Ann N Y Acad Sci. 920:93-99.

Bass, J, Turck, C, Rouard M, and Steiner, DF. 2000.  Furin-mediated processing in the early secretory pathway: sequential cleavage and degradation of the insulin receptor. Proc Natl Acad Sci USA.  97(22):11905-11909.

Kim, SH, Wang, R, Gordon, DJ, Bass, J, Steiner, DF, Thinakaran, G, Meredith, SC, and Sisodia, SS. 1999. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci. 2(11):984-988.

Rouard, M, Bass, J*, Grigorescu, F, Garrett, TPJ, Ward, CW, Lipkind, G, Jaffiole, C, Steiner, DF, and Bell, GI. 1999. Congenital insulin resistance associated with a conformational alteration in a conserved b-sheet in the insulin receptor L1 domain. (*contributed equally). J Biol Chem. 274(26):18487-18491.

Bass, J, Chiu, G, Argon, Y, and Steiner, DF. 1998. Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization. J Cell Biol. 141(3):637-646.

Kristensen,C,  Kjeldsen, T, Wiberg, FC, Schaffer, L, Hach, M,Havelund, S, Bass, J, Steiner, DF, and Andersen, AS. 1997.  Alanine scanning mutagenesis of insulin. J Biol Chem. 272(20):12978-12983.

Bass, J, Kurose, T, Pashmfouroush, M, and Steiner, DF. 1996. Fusion of insulin receptor ectodomains to Immunoglobulin constant domains reproduces high-affinity insulin binding in vitro. J Biol Chem. 271(32):19367-19375.  

 

INVITED REVIEWS AND COMMENTARIES:

Cederroth, CR, Albrecht, U, Bass, J, Brown, SA, Dyhrfjeld-Johnsen, J, Gachon, F, Green, CB, Hastings, MH, Helfrich-Förster, C, Hogenesch, JB, Lévi, F, Loudon, A, Lundkvist, GB, Meijer, JH, Rosbash, M, Takahashi, JS, Young, M, Canlon, B. Medicine in the fourth dimension. Cell Metab.2019 Aug 6 30(2):238-250. doi:10.1016/j.cmet.2019.06.019

Cedernaes, J, Waldeck, N, Bass, J. 2019. Neurogenetic basis for circadian regulation of metabolism by the hypothalamus. Invited Review. Genes Dev. 2019 Sep 1;33(17-18):1136-1158. doi:10.1101/gad.328633.119

Weidemann, BJ, Ramsey, KM, Bass, J. A day in the life of chromatin: how enhancer-promoter loops shape daily behavior. Invited Commentary. Genes Dev. 2018 Mar 1;32(5-6):321-323. doi: 10.1101/gad.314187.118.

Bass, J.2017. The circadian clock system’s influence in health and disease. Genome Med. 9:94, doi:/10.1186/s13073-017-0485-2

Bass, J, Lazar, MA. 2016. Circadian time signatures of fitness and disease. Invited Review. Science 354 (6315), 994-999. [doi: 10.1126/science.aah4965]

Perelis, M, Ramsey, KM, Marcheva, B, Bass, J. 2016. Circadian Transcription from Beta Cell Function to Diabetes Pathophysiology. Body Clocks Review Series. J Biol Rhythms. 2016 Aug;31(4):323-36. doi: 10.1177/0748730416656949

Cedernaes, J, Bass, J. 2016. Decoding Obesity in the Brainstem. eLife 2016;5:e16393. DOI:10.7554/eLife.16393

Bass, J. 2016. Targeting Time in Metabolic Therapeutics. Invited Review. Cell Metabolism. 2016 Apr 12;23(4):575-7. http://dx.doi.org/10.1016/j.cmet.2016.03.011

Perelis, M, Ramsey, KM, Bass, J. 2015. The molecular clock as a metabolic rheostat. Diabetes Obes Metab. 2015 Sep;17 Suppl 1:99-105. doi: 10.1111/dom.12521

Maury, E, Hong, HK, Bass, J. 2014. Circadian Disruption in the Pathogenesis of Metabolic Syndrome. Diabetes Metab. pii: S1262-3636(13)00235-8. doi: 10.1016/j.diabet.2013.12.005.

Ramsey, KM, Affinati, AH, Peek, CB, Marcheva, B, Hong, HK, Bass, J. 2013. “Circadian Measurements of Sirtuin Biology” in Matthew D. Hirschey, Editor, Sirtuins: Methods and Protocols of Methods in Molecular Biology. Methods Mol Biol 1077:285-302

Bass, J. 2013. Forever (FGF) 21. Invited Commentary. Nature Medicine 19:1090-1092.

Bass, J. 2012. Circadian Topology of Metabolism. Invited Insight Review. Nature. Nov 15; 491:348-356

Bass, J. 2012. Time in a bottle. Invited Commentary. Nature. May 2;485(7396):45-6.

Peek, CB, Ramsey, KM, Marcheva, B, Bass J. 2012. Nutrient Sensing and the Circadian Clock. Trends Endocrinol Metab. 23(7):312-8. [Epub ahead of print: Mar 15]. Selected as one of TOP 10 TEM articles of 2012.

Bass, J. 2011. Physiology: On time metabolism. Invited Commentary. Nature. Dec 21;480(7378):466-7

Ramsey, KM, Bass J. Circadian Clocks in Fuel Harvesting and Energy Homeostasis.  Cold Spring Harb Symp Quant Biol. 76:63-72. doi: 10.1101/sqb.2011.76.010546

Huang, W, Ramsey, KM, Marcheva, B, Bass, J. 2011. Circadian Rhythms, Sleep, and Metabolism. J Clin Invest. Jun 1;121(6):2133-41

Marcheva, B, Ramsey, KM, Bass J. Circadian Genes and Insulin Extocytosis. 2011. Cellular Logistics. 1(1):32-36.

Bass, J, Takahashi JS. 2011. Circadian Rhythms: Redox Redux. Invited Commentary. Nature. 469: 476–8.

Takahashi, JS, Bass, J. 2010. Circadian Integration of Metabolism and Energetics. Science 330(6009): 1349-1354.

Bass, J. 2010. High glucose, no cry. Invited Commentary: Nat Med. 16(10):1152-6.

Maury, E, Ramsey, KM, Bass, J. 2010. Circadian Rhythms and Metabolic Syndrome. From Experimental Genetics to Human Disease. Invited Review: Circ Res. 106(3):447-62.

Marcheva, B, Ramsey KM, Affinati, AH, Bass, J. 2009. Clock Genes and Metabolic Disease. Invited Review: J Appl Physiol. 107(5):1638-46. Epub 2009 Aug 6.

Ramsey, KM, Bass, J. 2009. Obeying the clock yields benefits for metabolism. Invited Commentary. PNAS. 106(11):4069-4070. [Epub ahead of print March 10].

Green, C, Takahashi JS, Bass, J.  2008.  The meter of metabolism.  Invited review: Cell. (134):728-742.

Laposky AD, Bass J, Kohsaka A, Turek FW. 2007. Sleep and circadian rhythms: Key components in the regulation of energy metabolism. FEBS Lett. 582(1):142-151.

Moynihan Ramsey, K, Bass, J.  2007.  Lean gene and the clock machine.  Proc Natl Acad Sci USA 104(23):9553-9554

Moynihan Ramsey, K, Marcheva, B, Kohsaka, A, Bass, J.  2007.  The clockwork of metabolism. Annu Rev Nutr. 27:219-240.

Kohsaka, A, Bass, J.  2007. A Sense of Time: How molecular clocks organize metabolism.  Trends Endocrinol Metab.  18(1):4-11.

Bass, J, Turek, FW.  2005. Sleepless in America: A pathway to obesity and the metabolic syndrome? Arch Intern Med. 165(1):15-16.

 

BOOK CHAPTERS:

Cedernaes, J, Ramsey, KM, Bass, J. 2018. “The Role of Circadian Biology in Health and Disease“ in J. Larry Jameson, Sr. Editor, Harrison’s Principles of Internal Medicine, 20^thedition, vol.2 (McGraw-Hill Education, 2018), p. 3504-3515.

Peek, CB, Ramsey, KM, Levine D, Perelis, M, Bass, J. 2014. “Circadian regulation of cellular physiology” in Amita Sehgal, Editor, Circadian Rhythms and Biological Clocks of Methods in Enzymology (Elsevier, 2014), p. 165-184.

Marcheva, B, Ramsey, KM, Peek, CB, Affinati, A, Maury, E, Bass, J. 2013. “Circadian Clocks and Metabolism” in Martha Merrow and Achim Kramer, Editors, Handbook of Experimental Pharmacology: Circadian Clocks (Springer, 2013), p. 127-155.

Hong, HK, Huang, W, Ramsey, KM, Marcheva, B, Bass, J. 2012. “Clock Genes and Energy Metabolism” in Priyattam J. Shiromani, Tamas Horvath, Susan Redline and Eve van Cauter, Editors, Sleep Loss and Obesity: Intersecting Epidemics (Springer, 2012), p. 13-32.

Maury, E, Ramsey, KM, Bass, J. “Sleep, Circadian Rhythms and Metabolism” in Rexford S. Ahima, Editor-in-Chief, Metabolic Basis of Obesity (Springer, 2011), p. 229-255.

Ramsey, KM, Bass, J. “Animal Models for Disorders of Chronobiology: Cell and Tissue” in Meir Kryger, Editor-in-Chief, Principles and Practice of Sleep Medicine, Fifth Edition (Elsevier, 2010), p. 463-469

Arble DM, Ramsey KM, Bass J, and Turek FW. “Circadian Disruption and Metabolic Disease: Findings from Animal Models”, Best Practice & Research Clinical Endocrinology & Metabolism (Elsevier, 2010), 24(5):785-800.

Kohsaka, A. and Bass, J. “Clock genes and metabolic regulation” in Larry R. Squire, Editor-in-Chief, Encyclopedia of Neuroscience (Oxford: Academic Press, online October 2008), p.1023-1029

Bass, J. and Steiner, DF. “Insulin receptor folding”. In Insulin signaling: from cultured cells to animal models.  (New York: Harwood Academic Presents, 2002) p. 19-35.