Publications

Google-Scholar/Arango

  • Gantner BN, Palma FR, Pandkar MR, Sakiyama MJ, Arango D, DeNicola G, Gomes AP, Bonini MG. (2024). Metabolism and epigenetics: drivers of tumor cell plasticity and treatment outcomes. Trends in Cancer. DOI: 10.1016/j.trecan.2024.08.005

  • Chen C, Masotti M, Shepard N, Promes V, Tombesi G, Arango D, Manzoni C, Greggio E, Hilfiker S, Kozorovitskiy Y, Parisiadou L. (2024). LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons. bioRxiv. doi: 10.1101/2024.06.06.597594.

  • Dalhat MH, Narayan S, Serio H, Arango D. (2024). Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10. Oncogene. 43,1077-1086. DOI: 10.1038/s41388-024-02975-9

  • Beiki H, Sturgill D, Arango D, Relier S, Schiffers S, Oberdoerffer S. (2024). Detection of ac4C in human mRNA is preserved upon data reassessment. Mol Cell. 84,1611-1625.e3. DOI: 10.1016/j.molcel.2024.03.018.

  • Ramachandran K, Futtner C, Sommars M, Quattrocelli M, Omura Y, Fruzyna E, Wang J, Waldeck N, Senagolage M, Dr Carmen Telles, Demonbreun A, Prendergast E, Nicola Lai N, Arango D, Bederman I, McNally E, Barish G. (2024). Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis. Nat Metab. 6,304-322. DOI: 10.1038/s42255-024-00983-3

  • Sudhakaran M, Garcia-Navarrete T, Guerra-Mejia K, Mukundi E, Eubank TD, Grotewold E, Arango D#, Doseff A#. (2023). Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer. Cell Death Dis. 14,824 DOI: 10.1038/s41419-023-06342-6. # Co-corresponding

  • Patrasso EA, Raikundalia S, Arango D. (2023). Regulation of the epigenome through RNA modifications. Chromosoma. 132, 231-246. DOI: 10.1007/s00412-023-00794-7

  • Sturgill D*#, Arango D*#, Oberdoerffer S#. (2022). Protocol for base resolution mapping of ac4C using RedaC:T-seq. STAR Protocols. 3, 101858. DOI: 10.1016/j.xpro.2022.101858. *Shared first authorship. # Co-corresponding

  • Arango D*, Sturgill D*, Yang R, Kanal T, Bauer P, Roy J, Wang M, Hosogane M, Schiffers S, Oberdoerffer S. (2022). Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine. Mol Cell. 82, 2797-2814. DOI: 10.1016/j.molcel.2022.05.016. *Shared first authorship.

  • Voss OH*, Arango D*, Tossey JC, Villalona-Calero MA, Doseff A. (2021). Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis. Cell Death Dis 12 (4), 287. DOI: 10.1038/s41419-021-03567-1. *Shared first authorship.

  • Arango D, Sturgill D, Oberdoerffer S. (2019). Immunoprecipitation and Sequencing of Acetylated RNA. Bio-protocol 9 (12), e3278. DOI: 10.21769/BioProtoc.3278

  • Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair W, Nanan KK, Mandler MD, Fox SD, Zengeya T, Andresson T, Meier J, Coller J, Oberdoerffer S. (2018). Acetylation of Cytidine in mRNA Promotes Translation Efficiency. Cell 175 (7), 1872-1886. DOI: 10.1016/j.cell.2018.10.030

  • Thomas JM, Briney CA, Nance KD, Lopez JE, Thorpe AL, Fox SD, Bortolin-Cavaille M, Sas-Chen A, Arango D, Oberdoerffer S, Cavaille J, Andresson T, Meier JL. (2018). A Chemical Signature for Cytidine Acetylation in RNA. J Am Chem Soc 140 (40), 12667-12670. DOI: 10.1021/jacs.8b06636

  • Sinclair WR, Arango D, Shrimp JH, Zengeya TT, Thomas MM, Montgomery DC, Fox SD, Andresson T, Oberdoerffer S, Meier JL. (2017). Profiling Cytidine Acetylation with Specific Affinity and Reactivity. ACS Chem Biol 12 (12), 2922-2926. DOI: 10.1021/acschembio.7b00734

  • Cardenas C*, Arango D*, Nicholas C*, Duarte S, Nouvo GJ, Voss OH, Gonzalez-Mejia ME, Guttridge DC, Grotewold E, Doseff AI. (2016). Dietary Apigenin Exerts Immune-Regulatory Activity in Vivoby Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function. Int J Mol Sci 17 (3), 323. DOI: 10.3390/ijms17030323. *Shared first authorship.

  • Arango D, Diosa-Toro M, Rojas-Hernandez LS, Cooperstone JL, Schwartz SJ, Mo X, Jiang J, Schmittgen TD, Doseff AI. (2015). Dietary apigenin reduces LPS-induced expression of mir-155 restoring immune balance during inflammation. Mol Nutr Food Res 59 (4) 763-772. DOI: 10.1002/mnfr.201400705

  • Arango D*, Morohashi K*, Yilmaz A, Kuramochi K, Parihar A, Brahimaj B, Grotewold E, Doseff AI. (2013). Molecular bases for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets. Proc Natl Acad Sci 110 (24) E2153-E2162. *Shared first authorship. DOI: 10.1073/pnas.1303726110

  • Duarte S*, Arango D*, Parihar A, Hamel P, Yasmeen R, Doseff AI. (2013). Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function. Int J Mol Sci 14 (9) 17664-17679. DOI: 10.3390/ijms140917664. *Shared first authorship.

  • Arango D, Parihar A, Villamena FA, Wang L, Freitas MA, Grotewold E, Doseff AI. (2012). Apigenin induces DNA damage through the PKCd-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair. Biochem Pharmacol 84 (12): 1571-1580. DOI: 10.1016/j.bcp.2012.09.005

  • Hostetler G, Riedl K, Cardenas H, Diosa-Toro M, Arango D, Schwartz SJ, Doseff AI. (2012). Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol Nutr Food Res 56 (4): 558-569. DOI: 10.1002/mnfr.201100596