312 Growth and Remodeling of Living Matter

Michael Sacks, ICES/University of Texas at Austin

Reza Avaz, ICES/University of Texas at Austin

Joao Soares, Virginia Commonwealth University

Living matter can continuously grow and remodel under development of diseases, environmental changes, and mechanical stimuli. The biomechanical and biochemical mechanisms that drive growth and remodeling (G&R) take place at different length and time scales comprising the cellular, tissue, and organ levels. The identification and simulation of such mechanisms remain elusive and requires multi-scale, integrated computational-experimental approaches. Such approaches are essential for the development of accurate simulations of G&R processes, which will be helpful in facilitating diagnosis of disease and its progression, as well as in optimizing the efficiency of clinical interventions. This symposium is intended to present the state-of-the-art theoretical and computational works on the biomechanics of growth and remodeling and to explore potential applications.

Keywords: human health, biomechanics

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