Publications

Scheidt Group Publications

147

Murauski, K. J. R.; Walden, D. M.; Cheong, P. H-Y.; Scheidt, K. A.* “A Cooperative Ternary Catalysis System for Asymmetric Lactonizations of α-Ketoesters,” Adv. Synth. Catal. 2017, 359, 3713-3719.

146

Hovey, M. T.; Cohen, D. T.; Walden, D. M.; Cheong, P. H-Y.; Scheidt, K. A.* “A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products,” Angew. Chem. Int. Ed. 2017, 56, 9864-9867.

Featured in:  Carreira, E. M.; Sievertsen, N. Synfacts 2017, 13 (10), 1012.

145

Walden, D. M.; Johnston, R. C. Jaworski, A. A.; Hovey, M. T.; Meyer, M. P.; Scheidt, K. A.* and Cheong, P. H.* “Formation of Aza-ortho-quinone Methides Under Room Temperature Conditions: Cs2CO3 Effect,” J. Org. Chem. 2017, 82, 7183-7189.

144

Wang, M.; Barsoum, D.; Schwamb, C. B.; Cohen, D. T.; Goess, B. C.; Riedrich, M.; Chan, A.; Maki, B. E.; Mishra, R. K.; Scheidt, K. A.* “Catalytic, Enantioselective β-Protonation through a Cooperative Activation Strategy,” J. Org. Chem. 2017, 82, 4689-4702.

143

Beniah, G.; Chen, X.; Uno, B. E.; Liu, K.; Leitsch, E. K.; Jeon, J.; Heath, W. H.; Scheidt, K. A.; Torkelson, J. M.* “Combined Effects of Carbonate and Soft-Segment Molecular Structures on the Nanophase Separation and Properties of Segmented Polyhydroxyurethane,” Macromolecules 2017, 50, 3193-3203.

142

Deibler, K. K.; Mishra, R.K.; Clutter, M. R.; Antanasijevic, A. Bergan, R.; Caffrey, M.; Scheidt, K. A.* ”A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family,” ACS Chem. Biol. 2017, 12, 1245-1256.

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141

Betori, R. C.; Miller, E. R.; Scheidt, K. A., “A Biocatalytic Route to Highly Enantioenriched β-Hydroxydioxinones,” Adv. Synth. Cat2017, 359, 1131-1137.

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140

Beniah, G.; Uno, B. E.; Lan, T.; Jeon, J.; Heath, W. H.; Scheidt, K. A.; Torkelson, J. M. “Tuning Nanophase Separation Behavior in Segmented Polyhydroxyurethane via Judicious Choice of Soft Segment,” Polymer 2017, 110, 218-227.

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139 Beniah, G. Liu, K.; Heath, W. H.; Miller, M. D.; Scheidt, K. A.; Torkelson, J. M.* “Novel Thermoplastic Polyhydroxyurethane Elastomers as Effective Damping Materials over Broad Temperature Ranges,” Eur. Polymer J.  2016, 84, 770-783.

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 138

Leitsch, E.; Beniah, G. Liu, K.; Lan, T.; Heath, W.; Scheidt, K. A.; Torkelson, J.* “Non-Isocyanate Thermoplastic Polyhydroxyurethane Elastomers via Cyclic Carbonate Aminolysis: Critical Role of Hydroxyl Groups in Controlling Nanophase Separation,” ACS Macro Letters 2016, 5, 424-429.

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137

Wang, M. H.; Scheidt, K. A. “Cooperative Catalysis and Activation with N-Heterocyclic Carbenes,” Angew. Chem. Int. Ed. 20165, 424-429.

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136

Jaworski, A. A.; Scheidt, K. A. “Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis,” J. Org. Chem. 2016, 81, 10145-10153.

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135

Sharma, H. A.; Hovey, M. T.; Scheidt, K. A.. “Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes,” Chem. Commun. 2016, 52, 9283-9286.

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134

Hall, E. A.; Redfern, L. R.; Wang, M. H.; Scheidt, K. A.. “Lewis Acid Activation of a Hydrogen Bond Donor Metal–Organic Framework for Catalysis,” ACS Catal. 2016, 6, 3248-3252.

Featured in:  Uozumi, Y.; Yamada, Y. M. A.; Ishii, R. Synfacts 201612 (8), 875.

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133 Zhu, J.; Mishra, R. K.; Schiltz, G. E.; Makanji, Y.; Scheidt, K. A.; Mazar, A. P.; Woodruff, T. K. “Virtual High-Throughput Screening To Identify Novel Activin Antagonists,” J. Med. Chem. 2015, 58 (14), 5637-5648.

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132

Wang, M. H.; Cohen, D.T.; Schwamb, C. B. Mishra, R. K.; Scheidt, K. A. “Enantioselective β-Protonation by a Cooperative Catalysis Strategy,” J. Am. Chem. Soc. 2015, 137, 5891-5894.

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131

Younai, A.; Zeng, B.-S.; Meltzer, H. Y.; Scheidt, K. A. “Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis,” Angew. Chem. Int. Ed. 2015, 54, 6900-6904.

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130

McDonald, B. R.; Scheidt, K. A. “Pyranone Natural Products as Inspirations for Catalytic Reaction Discovery and Development,” Acc. Chem. Res. 2015, 48 (4), 1172-1183.

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129 Lombardo, V. M., Dhulst, E. A.; Leitch, E. K.; Wilmot, N.; Heath, W. H.; Gies, A. P.; Miller, M. D.; Torkelson, J. M.; Scheidt, K. A. “Cooperative Catalysis of Cyclic Carbonate Ring Opening: Application Towards Non-Isocyanate Polyurethane Materials,” Eur. J. Org. Chem. 2015, 2791-2795.
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128

Check, C. T.; Jang, K. P.; Schwamb, C. B.; Wong, A. S.; Wang, M. H.; Scheidt, K. A. “Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis,” Angew. Chem. Int. Ed. 2015, 54, 4264-4268.

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127

Lee, A.; Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Enantioselective Annulations: A Dual Activation Strategy for a Formal [4+2] Addition for Dihydrocoumarins,” Chem. Commun. 2015, 51, 3407-3410.

Graphical abstract: N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

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126

Cohen, D. T.; Johnston, R. C.; Rosson, N. T.; Cheong, P. H.-Y.; Scheidt, K. A. “Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application,” Chem. Commun. 2015, 51, 2690-2693.

Graphical abstract: Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

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125

McDonald, B. R.; Nibbs, A. E.; Scheidt, K. A. “A Biomimetic Strategy to Access the Silybins: Total Synthesis of (—)-Isosilybin A,” Org. Lett. 2015, 17 (1), 98-101.

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124 Liu, K.; Hovey, M. T.; Scheidt, K. A. “A Cooperative N-Heterocyclic Carbene/Palladium Catalysis System,” Chem. Sci. 2014, 5 (10), 4026-4031. Abstract
123 Lee, A.; Younai, Y.; Price, C. K.; Izquierdo, J.; Mishra, R. K.; Scheidt, K. A. “Enantioselective Annulations for Dihydroquinolones by in Situ Generation of Azolium Enolates,” J. Am. Chem. Soc. 2014, 136 (30), 10589-10592. Abstract
122 Hovey, M. T.; Check, C. T.; Sipher, A. F.; Scheidt, K. A. “N-Heterocyclic-Carbene-Catalyzed Synthesis of 2-Aryl Indoles,” Angew. Chem. Int. Ed. 2014, 53, 9603–9607. Abstract
121 Lee, A.; Scheidt, K. A. “A Cooperative N-Heterocyclic Carbene/Chiral Phosphate Catalysis System for Allenolate Annulations,” Angew. Chem. Int. Ed. 2014, 53, 7594-7598. Abstract
120 Zeng, B.-S.; Yu, X.; Siu, P. W.; Scheidt, K. A. “Catalytic Enantioselective Synthesis of 2-Aryl Chromenes,” Chem. Sci. 2014, 5 (6), 2277-2281. Abstract
119 Johnston, R. C.; Cohen, D. T.; Eichman, C. C.; Scheidt, K. A.; Cheong, P. “Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis,” Chem. Sci. 2014, 5, 1974-1982. Abstract
118 Lukas, T. J.; Schiltz, G.; Arrat, H.; Scheidt, K. A.; Siddique, T. “Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression,” Bioorg. Med. Chem. Lett. 2014, 24, 1532-1537. Abstract
117 Jang, K. P.; Hutson, G. E.; Johnston, R. C.; McCusker, E. O.; Cheong, P. H.-Y.; Scheidt, K. A. “Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst,” J. Am. Chem. Soc. 2014, 136, 76-79.
116 McCusker, E. O.; Scheidt, K. A. “Enantioselective N-Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones,” Angew. Chem. Int. Ed. 2013, 52, 13616-13620.
115 Lombardo, V. M.; Thomas, C. D.; Scheidt, K. A. “A Cascade Isomerization/Prins Strategy through Iridium(III)/Brønsted Acid Cooperative Catalysis,” Angew. Chem Int. Ed. 2013, 52, 12910-12914.  
114 Siu, P. W.; Brown,Z. J.; Farha, O. K.; Hupp, J. T.; Scheidt, K. A. “A Mixed Dicarboxylate Strut Approach To Enhancing Catalytic Activity Of A De Novo Urea Derivative Of Metal-Organic Framework Uio-67,” Chem. Commun. 2013, 49, 10920-10922.
113 Katz, M. J.; Brown, Z. J.; Colón, Y. J.; Siu, P. W.; Scheidt, K. A.; Snurr, R. Q.; Hupp, J. T.; Farha, O. K. “A facile synthesis of UiO-66, UiO-67 and their derivatives,” Chem. Commun. 2013, 49, 9449-9451.  
112 Krishna, S. N.; Luan, C.-H.; Mishra, R. K.; Xu, L.; Scheidt, K. A.; Anderson, W. A.; Bergan, R. C. “A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated kinase kinase 4,” PLoS One 2013, 8(12).  
111 Izquierdo, J.; Orue, A.; Scheidt, K. A. “A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations,“ J. Am. Chem. Soc. 2013, 135, 10634-10637.
110 Farmer, R. L.; Scheidt, K. A. “A Concise Enantioselective Synthesis and Cytotoxic Evaluation of the Anticancer Rotenoid Deguelin Enabled by a Tandem Knoevenagel/Conjugate Addition/Decarboxylation Sequence,“ Chem. Sci. 2013, 4 (8), 3304-3309.
109 Lalonde, M. B.; Getman, R.; Lee, J. Y.; Roberts, J.; Sarjeant, A.; Scheidt, K. A.; Georgiev, P. A.; Embs, J. P.; Eckert, J.; Farha, O. K.; Snurr, R. Q.; Hupp, J. T. “A Zwitterionic Metal-Organic Framework with Free Carboxylic Acid Sites that Exhibits Enhanced Hydrogen Adsorption Energies,“ CrystEngComm. 2013, 15, 9408-9414.
108 Izquierdo, J.; Hutson, G. E.; Cohen, D. T.; Scheidt, K. A. “A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis,“ Angew. Chem. Int. Ed. 2012, 51, 11686-11698.
107 Lalonde, M. B.; Farha, O. K.; Scheidt, K. A.; Hupp, J. T. “N-Heterocyclic Carbene-Like Catalysis by a Metal-Organic Framework (MOF) Material,” ACS Catalysis 2012, 2 (8), 1550–1554. Abstract
106 Cui, J.; Chai, D. I.; Miller, C.; Hao, J.; Thomas, C.; Wang, J.; Scheidt, K. A.; Kozmin, S. A. “Assembly of Four Diverse Heterocyclic Libraries Enabled by Prins Cyclization, Au-Catalyzed Enyne Cycloisomerization, and Automated Amide Synthesis,” J. Org. Chem. 2012, 77, 7435–7470. Abstract
105 O’Bryan, E. A.; Scheidt, K. A. “Acyloin Coupling Reactions,” Comprehensive Organic Synthesis II. Vol 3, Marek, I., Knochel, P. eds. 2012, 621-655.
104 Cohen, D. T.; Eichman, C. C.; Phillips, E. M.; Zarefsky, E. R.; Scheidt, K. A. “Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones,” Angew. Chem. Int. Ed. 2012, 51, 7309–7313. Abstract
103 Scheidt, K. A.; Phillips, E. M.; Dugal-Tessier, J. “N-Heterocyclic Carbene-Catalyzed Aldol Desymmetrizations,” in Asymmetric Synthesis- More Methods and Applications, Eds. Christmann and Bräse. Wiley-VCH, 2012.
102 Dugal-Tessier, J.; O’Bryan, E. A.; Schroeder, T. B. H.; Cohen, D. T.; Scheidt, K. A. “An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones,” Angew. Chem. Int. Ed. 2012, 51, 4963-4967. Abstract
101 Cardinal-David, B.; Scheidt, K. A. “Carbene Catalysis: Beyond the Benzoin and Stetter Reactions,” in Inventing Reactions: Topics in Organometallic Chemistry, Ed. Goosen. Springer, 2012.
100 Roberts, J. M.; Fini, B. M.; Sarjeant, A. A.; Farha, O. K.; Hupp, J. T.; Scheidt, K. A. “Urea Metal–Organic Frameworks as Effective and Size Selective Hydrogen–Bond Catalysts,” J. Am. Chem. Soc. 2012, 134, 3334-3337. Abstract
99 Brekan, J. A.; Chernyak, D.; White, K. L.; Scheidt, K. A. “Lewis Base-Promoted Carbon-Carbon sp3–sp3 Coupling Reactions of α-Silyl Silylethers,” Chem. Sci. 2012, 3, 1205-1210. Abstract
98
Nibbs, A. E.; Scheidt, K. A. “Asymmetric Methods for the Synthesis of Flavanones, Chromanones, and Azaflavanones,” Eur. J. Org. Chem. 2012, 3, 449-462. Abstract
97 Cohen, D. T.; Scheidt, K. A. “Cooperative Lewis Acid/N-Heterocyclic Carbene Catalysis,” Chem. Sci. 2012, 3, 53-57. Abstract
96 Sonntag, M. D.; Klingsporn, J. M.; Garibay, L. J.; Roberts, J. M.; Dieringer, J. A.; Seideman, T.; Scheidt, K. A.; Jensen, L.; Schatz, G. C.; Van Duyne, R. P. “Single-Molecule Tip-Enhanced Raman Spectroscopy,” J. Phys. Chem. C. 2012, 116, 478-483. Abstract
95 Roberts, J. M.; Farha, O. K.; Sarjeant, A. A.; Hupp, J. T.; Scheidt, K. A. “Two Azolium Rings are Better than One: A Strategy for Controlling Catenation and Morphology in Zn and Cu Metal-Organic Frameworks,” Cryst. Growth Des. 2011, 11, 4747-4750.
94 Eichman, C. C.; Cohen, D. T.; Scheidt, K. A. “(S)-5-Benzyl-2-mesityl-6,6-dimethyl-6,8-dihydro-5H-[1,2,4]triazolo[3,4-C][1,4]oxazin-2-ium tetrafluoroborate,” The Electronic Encyclopedia of Reagents for Organic Synthesis, 2011.
93 Atienza, R. L.; Scheidt, K. A. “N-Heterocyclic Carbene-Promoted Rauhut-Currier Reactions between Vinyl Sulfones and α,β-Unsaturated Aldehydes,” Aust. J. Chem. 2011, 64, 1158-1164.
92 Crane, E. A.; Zabawa, T. P.; Farmer, R. L. Scheidt, K. A. “Enantioselective Synthesis of (–)-Exiguolide by Iterative Stereoselective Dioxinone-Directed Prins Cyclizations,” Angew. Chem. Int. Ed. 2011, 50, 9112-9115.
91 Atienza, R. L.; Roth, H. R.; Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Rearrangements of Vinyl Sulfones,” Chem. Sci. 2011, 2, 1772-1776
90 Wang, J.; Crane, E. A.; Scheidt, K. A. “Highly Stereoselective Brønsted Acid Catalyzed Synthesis of Spirooxindole Pyrans,” Org. Lett. 2011, 13, 3086-3089. Abstract
89 Tenenbaum, J. M.; Morris, W. J.; Custar, D. W.; Scheidt, K. A. “Synthesis of (–)-Okilactomycin by a Prins-Type Fragment-Assembly Strategy,” Angew. Chem. Int. Ed. 2011, 50, 5892-5895. Abstract
88 Kleinman, S. L.; Ringe, E.; Valley, N.; Wustholz, K. L.; Phillips, E. M.; Scheidt, K. A.; Schatz, G. C.; Van Duyne, R. V. “Single-Molecule Surface-Enhanced Raman Spectroscopy of Crystal Violet Isotopologues: Theory and Experiment,” J. Am. Chem. Soc. 2011, 133, 4115-4122. Abstract
87 Cohen, D.; Cardinal-David, B.; Roberts, J. M.; Sarjeant, A. A.; Scheidt, K. A. “NHC-Catalyzed/Titanium(IV)–Mediated Highly Diastereo- and Enantioselective Dimerization of Enals,” Org. Lett. 2011, 13, 1068-1071. Abstract
86 Cohen, D.; Cardinal-David, B.; Scheidt, K. A. “Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters,” Angew. Chem. Int. Ed. 2011, 50, 1678-1682. Abstract
85 Phillips, E. M.; Riedrich, M.; Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Conjugate Additions of Alcohols,” J. Am. Chem. Soc. 2010, 132, 13179–13181. Abstract
84 Crane, E. A.; Scheidt, K. A. “Prins-Type Macrocyclizations as an Efficient Ring-Closing Strategy in Natural Product Synthesis,” Angew. Chem. Int. Ed. 2010, 49, 8316 – 8326. Abstract
83 Farmer, R. L.; Biddle, M. M.; Nibbs, A. E.; Huang, X.; Bergan, R. C.; Scheidt, K. A. “Concise Syntheses of the Abyssinones and Discovery of New Inhibitors of Prostate Cancer and MMP-2 Expression,” ACS Med. Chem. Lett. 2010, 1, 400–405. Abstract
82 Scheidt, K. A. “Amide Bonds Made in Reverse,” Nature News and Views 2010, 465, 1020–1022. Abstract
81 Cardinal-David, B.; Raup, D. E. A; Scheidt, K. A. “Cooperative N-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenlates,” J. Am. Chem. Soc. 2010, 132, 5345–5347. Abstract
80 Phillips, E. M.; Roberts, J. M.; Scheidt, K. A. “Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization,” Org. Lett. 2010, 12, 2830–2833. Abstract
79 Raup, D. E. A.; Cardinal-David, B.; Holte, D.; Scheidt, K. A. “Cooperative Catalysis by Carbenes and Lewis Acids in a Highly Stereoselective Route to γ-Lactams,” Nat. Chem. 2010, 2, 766-771. Abstract
78 Brekan, J. A.; Reynolds, T. E; Scheidt, K. A. “Enantioselective Synthesis of Substituted Indanones from Silyloxyallenes,” J. Am. Chem. Soc. 2010, 132, 1472-1473. Abstract
77 Phillips, E. M.; Chan, A.; Scheidt, K. A. “Discovering New Reactions with N-Heterocyclic Carbene Catalysis,” Aldrichimica Acta 2009, 42, 55-66. Abstract
76 Kawanaka, Y.; Phillips, E. M.; Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes,” J. Am. Chem. Soc. 2009, 131, 18028-18029. Abstract
75 Nibbs, A. E.; Maize, A. L.; Herter, R. M.; Scheidt, K. A. “Catalytic Asymmetric Alkylation of Substituted Isoflavanones,” Org. Lett. 2009, 11, 4010-4013. Abstract
74 Lee, J. Y.; Roberts, J. M.; Farha, O. K.; Sarjeant, A. A.; Scheidt, K. A.; Hupp, J. T. “Synthesis and Gas Sorption Properties of a Metal-Azolium Framework (MAF) Material,” Inorg. Chem. 2009, 48, 9971-9973 Abstract
73 Maki, B. E.; Patterson, E. V.; Cramer, C. J.; Scheidt, K. A. “Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents,” Org. Lett. 2009, 48, 3942-3945. Abstract
72 Custar, D. W.; Zabawa, T. P.; Hines, J.; Crews, C. M.; Scheidt, K. A. “Total Synthesis and Structure-Activity Investigation of the Marine Natural Product Neopeltolide,” J. Am. Chem. Soc. 2009, 131, 12406-12414. Abstract
71 Lettan, R. B., II; Galliford, C. V.; Woodward, C. C.; Scheidt, K. A. “Amide Enolate Additions to Acylsilanes: In Situ Generation of Unusual and Stereoselective Homoenolate Equivalents,” J. Am. Chem. Soc. 2009, 131, 8805-8814. Abstract
70 Lee, J. Y.; Farha, O. K.; Roberts, J. T; Scheidt, K. A.; Nguyen, S. T.; Hupp, J. T. “Metal-Organic Framework Materials as Catalysts,” Chem. Soc. Rev. 2009, 38, 1450-1459. Abstract
69 Xu, L.; Ding, Y.; Catalona, W. J.; Yang, X. J.; Anderson, W. F.; Jovanovic, B.; Wellman, K.; Kilmer, J.; Huang, X.; Scheidt, K. A.; Montgomery, R. B.; Bergan, R. C. “MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells,” J. Nat. Can. Inst. 2009, 101, 1141-1155. Abstract
68 Maki, B. E.; Scheidt, K. A. “Single-Flask Synthesis of N-Acylated Indoles by Catalytic Dehydrogenative Coupling with Primary Alcohols,” Org. Lett. 2009, 11, 1651-1654. Abstract
67 Phillips, E. M.; Wadamoto, M.; Roth, H. S.; Ott, A. W.; Scheidt, K. A. “NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins,” Org. Lett. 2009, 11, 105-108. Abstract
66 Mathies, A. K.; Mattson, A. E.; Scheidt, K. A. “Intermolecular Crossed-Acyloin Reactions by Fluoride-Promoted Additions of O-Silyl Thiazolium Carbinols,” Synlett, Invited Contribution to Special Edition For Journal Awardees, 2009, 2009, 377-383. Abstract
65 Phillips, E. M.; Wadamoto, M.; Scheidt, K. A. “Synthesis of Enantioenriched α,α-Disubstituted Cyclopentenes Catalyzed by N-Heterocyclic Carbenes,” Synthesis, Invited PSP article, 2009, 687-690. Abstract
64 Maki, B. E.; Chan, A.; Phillips, E. M.; Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Oxidations,” Tetrahedron, invited article for special Justin DuBois Issue, 2009, 65, 3102-3109. Abstract
63 Reynolds, T. E.; Binkley, M. S.; Scheidt, K. A. “Highly Selective α-Acylvinyl Anion Additions to Imines,” Org. Lett. 2008, 10, 5227-5230 Abstract
62 Gibbs-Davis, J. M.; Kruk, J. J.; Konek, C. T.; Scheidt, K. A.; Geiger, F. M. “Jammed Acid-Base Reactions at Interfaces,” J. Am. Chem. Soc. 2008, 130, 15444-15447. Abstract
61 Stokes, G. Y.; Buchbinder, A. M.; Gibbs-Davis, J. M.; Scheidt, K. A.; Geiger, F. M. “Heterogeneous Ozone Oxidation Reactions of 1-Pentene, Cyclopentene, Cyclohexene, and a Menthenol Derivative Studied by Sum Frequency Generation,”J. Phys. Chem. A. 2008, 112, 11688-11698. Abstract
60 Maki, B. E. and Scheidt, K. A. “N-Heterocyclic Carbene-Catalyzed Oxidation of Unactivated Aldehydes to Esters,” Org. Lett. 2008, 10, 4331-4334. Abstract
59 Reynolds, T. E.; Binkley, M. S.; Scheidt, K. A. “Lewis Acid-Catalyzed Conjugate Additions of Silyloxyallenes: A Selective Solution to the Intermolecular Rauhut−Currier Problem,” Org. Lett. 2008, 10, 2449–2452. Abstract
58 Maki, B. E.; Chan. A.; Scheidt, K. A. “Protonation of Homoenolate Equivalents Generated by N-Heterocyclic Carbenes,” Synthesis, invited Feature Article, 2008, 2008, 1306-1315. Abstract
57 Galliford, C. V. and Scheidt, K. A. “An Unusual Dianion Equivalent from Acylsilanes for the Synthesis of Substituted β-Keto Esters,” Chem. Commun. 2008, 16, 1926-1928. Abstract
56 Chan. A. and Scheidt, K. A. “Direct Amination of Homoenolates Catalyzed by N-Heterocyclic Carbenes,” J. Am. Chem. Soc. 2008, 130, 2740-2741. Abstract
55 Phillips, E. M.; Reynolds, T. E.; Scheidt, K. A. “Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed by N-Heterocyclic Carbenes,” J. Am. Chem. Soc. 2008, 130, 2416-2417. Abstract
54 Lettan II, R. B.; Woodward, C. C.; Scheidt, K. A. “Highly Stereoselective Synthesis of Substituted γ-Lactams From Acylsilanes,” Angew. Chem. Int. Ed. 2008, 47, 2294-2297. Abstract
53 Custar, D. W.; Zabawa, T. P.; Scheidt, K. A. “Total Synthesis and Structural Revision of the Marine Macrolide Neopeltolide,” J. Am. Chem. Soc. 2008, 130, 804-805. Abstract
52 Dieringer, J. A.; Lettan, R. B., II; Scheidt, K. A.; Van Duyne, R. P. “A Frequency Domain Existence Proof of Single-Molecule Surface-Enhanced Raman Spectroscopy,” J. Am. Chem. Soc. 2007, 129, 16249-16256. Abstract
51 Reynolds, T. E.; Scheidt, K. A. “Catalytic Enantioselective α-Acylvinyl Addition Reactions of Silyloxyallenes,” Angew. Chem Int. Ed. 2007, 46, 7806-7809. Abstract
50 Wadamoto, M.; Phillips, E.M.; Reynolds, T. E.; Scheidt, K. A. “Enantioselective Synthesis of α,α-Disubstituted Cyclopentenes by an N-Heterocyclic Carbene-Catalyzed Desymmetrization of 1,3-Diketones,” J. Am. Chem. Soc. 2007, 129, 10098-10099. Abstract
49 Scheidt, K. A. and Mattson, A. E. “5-(1,1-dimethylethyl)-5,6-dihydro-2-phenyl-(5S)-oxazolo[2,3-c]-1,2,4-triazolium tetrafluoroborate,” The Electronic Encyclopedia of Reagents for Organic Synthesis, 2007. Abstract
48 Reynolds, T. E.; Stern, C. A.; Scheidt, K. A. “N-Heterocyclic Carbene-Initiated α-Acylvinyl Anion Reactivity: Additions of α-Hydroxypropargylsilanes to Aldehydes,” Org. Lett. 2007, 9, 2581-2584. Abstract
47 Galliford, C. V.; Scheidt, K. A. “Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents,” Angew. Chem. Int. Ed. 2007, 46, 8748-8758. Abstract
46 Chan, A.; Scheidt, K. A. “Highly Stereoselective Formal [3+3] Cycloaddition of Enals and Azomethine Imines Catalyzed by N-Heterocyclic Carbenes,” J. Am. Chem. Soc. 2007, 129, 5334-5335. Abstract
45 Gibbs-Davis, J. M.; Hayes, P. L.; Scheidt, K. A.; Geiger, F. M. “Anion Chelation by Amino Acid-Functionalized Fused Quartz/Water Interfaces Studied by Nonlinear Optics,” J. Am. Chem. Soc. 2007, 129, 7175-7184. Abstract
44 Milgram, B. C.; Eskildsen, K.; Richter, S. M.; Scheidt, W. R.; Scheidt, K. A. “Microwave-Assisted Piloty–Robinson Synthesis of 3,4-Disubstitued Pyrroles,” J. Org. Chem. 2007, 72, 3941-3944. Abstract
43 Mattson, A. E.; Scheidt, K. A. “Nucleophilic Acylation of o-Quinone Methides: An Umpolung Strategy for the Synthesis of α-Aryl Ketones and Benzofurans,” J. Am. Chem. Soc. 2007, 129, 4508-4509. Abstract
42 Biddle, M. A.; Lin, M.; Scheidt, K. A. “Catalytic Enantioselective Synthesis of Flavanones and Chromanones,” J. Am. Chem. Soc. 2007, 129, 3830-3831. Abstract
41 Phillips, E. M.; Wadamoto, M.; Chan, A.; Scheidt, K. A. “Highly Enantioselective Intramolecular Michael Reaction Catalyzed by N-Heterocyclic Carbenes,” Angew. Chem. Int. Ed. 2007, 46, 3107-3110. Abstract
40 Galliford, C. V.; Scheidt, K. A. “Catalytic Multicomponent Reactions for the Synthesis of N-Aryl Trisubstituted Pyrroles,” J. Org. Chem. 2007, 72, 1811-1813. Abstract
39 Hayes, P. L.; Gibbs-Davis, J. M.; Musorrafiti, M. J.; Mifflin, A. M.; Scheidt, K. A.; Geiger, F. M. “Environmental Biogeochemistry Studied by Second Harmonic Generation: A Look at the Agricultural Antibiotic Oxytetracycline,” Invited contribution to the Kenneth B. Eisenthal Festschrift in for J. Phys. Chem. C. 2007, 111, 8796-8804. Abstract
38 Maki, B. E.; Chan, A.; Phillips, E. M.; Scheidt, K. A. “Tandem Oxidation of Allylic and Benzylic Alcohols to Esters Catalyzed by N-Heterocyclic Carbenes,” Org. Lett. 2007, 9, 371-374. Abstract
37 Lettan, R. B., II; Milgram, B. C.; Scheidt, K. A. “Synthesis of Acylsilanes from Morpholine Amides. Synthesis of 1-(Dimethyl(Phenyl)silyl)propan-1-one,” Org. Syn. 2007, 84, 22-31. Abstract
36 Voges. A.B.; Yin, G.; Gibbs-Davis, J. M.; Lettan, R. B., II; Bertin, P. A.; Pike, R. C.; Nguyen, S. T.; Scheidt, K. A.; Geiger, F. M. “Insights into Heterogeneous Atmospheric Oxidation Chemistry: Development of a Tailor-Made Synthetic Model for Studying Tropospheric Surface Chemistry,” J. Phys. Chem. C. Feature article, 2007, 111, 1567-1578. Abstract
35 Galliford, C. V.; Martenson, J. S.; Stern, C. A.; Scheidt, K. A. “A Highly Diastereoselective, Catalytic Three-Component Assembly Reaction for the Synthesis of Spiropyrrolidinyloxindoles,” Chem. Commun. 2007, 6, 631-633. Abstract
34 Lettan, R. B., II; Reyonlds, T. E.; Galliford, C. V.; Scheidt, K. A. “Synthesis of Tertiary β-Hydroxy Amides by Enolate Additions to Acylsilanes,” J. Am. Chem. Soc. 2006, 128, 15566-15567. Abstract
33 Scheidt, K. A. and Lettan II, R. B. “Triethoxysilane (Update),” The Electronic Encyclopedia of Reagents for Organic Synthesis, 2006. Abstract
32 Reynolds, T. E.; Bharadwaj, A. R.; Scheidt, K. A. “Stereoselective Lewis Acid-Catalyzed α-Acylvinyl Additions,” J. Am. Chem. Soc. 2006, 128, 15382-15383. Abstract
31 Mattson, A. E.; Bharadwaj, A. R.; Zuhl, A. M.; Scheidt, K. A. “Thiazolium-Catalyzed Additions of Acylsilanes: A General Strategy for Acyl Anion Addition Reactions,” J. Org. Chem. 2006, 71, 5715-5724. Abstract
30 Chan, A.; Scheidt, K. A. “Hydroacylation of Activated Ketones Catalyzed by N-Heterocyclic Carbenes,” J. Am. Chem. Soc. 2006, 128, 4558-4559. Abstract
29 Mattson, A. E.; Zuhl, A. M.; Reynolds, T. E.; Scheidt, K. A. “Direct Nucleophilic Acylation of Nitroalkenes Promoted by a Fluoride Anion/Thiourea Combination,” J. Am. Chem. Soc. 2006, 128, 4932-4933. Abstract
28 Graves, C. R.; Scheidt, K. A.; Nguyen, S. T. “Enantioselective MSPV Reduction of Ketimines Using 2-Propanol and (BINOL)AlIII,” Org. Lett. 2006, 8, 1229-1232. Abstract
27 Myers, M. C.; Bharadwaj, A. R; Milgram, B. C.; Scheidt, K. A. “Catalytic Conjugate Additions of Carbonyl Anions under Neutral Aqueous Conditions,” J. Am. Chem. Soc. 2005, 127, 14675-14680. Abstract
26 Lettan, R. B., II; Scheidt, K. A. “Lewis Base-Catalyzed Additions of Alkynes Using Trialkoxysilylalkynes,” Org. Lett. 2005, 7, 3227-3230. Abstract
25 Ballweg, D. M.; Miller, R. C.; Gray, D. L; Scheidt, K. A. “Stereoselective Synthesis of α-Silylamines by the Direct Addition of Silyl Anions to Activated Imines,” Org. Lett. 2005, 7, 1403-1406. Abstract
24 Morris, W. J.; Custar, D. W.; Scheidt, K. A. “Stereoselective Synthesis of Tetrahydropyran-4-ones from Dioxinones Catalyzed by Scandium(III) Triflate,” Org. Lett. 2005, 7, 1113-1116. Abstract
23 Chernick, E. T.; Ahrens, M. J.; Scheidt, K. A.; Wasielewski, M. R. “Copper-Promoted N-Arylations of Cyclic Imides within Six-Membered Rings: A Facile Route to Arylene-Based Organic Materials,” J. Org. Chem. 2005, 70, 1486-1489. Abstract
22 Chan, A.; Scheidt, K. A. “Conversion of α,β-Unsaturated Aldehydes into Saturated Esters: An Umpolung Reaction Catalyzed by Nucleophilic Carbenes,” Org. Lett. 2005, 7, 905-908. Abstract
21 Mattson, A. E.; Scheidt, K. A. “Catalytic Additions of Acylsilanes to Imines: An Acyl Anion Strategy for the Direct Synthesis of α-Amino Ketones,” Org. Lett. 2004, 6, 4363-4366. Abstract
20 Clark, C. T.; Milgram, B. C.; Scheidt, K. A. “Efficient Synthesis of Acylsilanes Using Morpholine Amides,” Org. Lett. 2004, 6, 3977-3980. Abstract
19 Bharadwaj, A. R.; Scheidt, K. A. “Catalytic Multicomponent Synthesis of Highly Substituted Pyrroles Utilizing a One-Pot Sila-Stetter/Paal–Knorr Strategy,” Org. Lett. 2004, 6, 2465-2468. Abstract
18 Mattson, A. E.; Bharadwaj, A. R.; Scheidt, K. A. “The Thiazolium-Catalyzed Sila-Stetter Reaction: Conjugate Addition of Acylsilanes to Unsaturated Esters and Ketones,” J. Am. Chem. Soc. 2004, 126, 2314-2315. Abstract
17 Clark, C. T.; Lake, J. F.; Scheidt, K. A. “Copper(I)-Catalyzed Disilylation of Alkylidene Malonates Employing a Lewis Base Activation Strategy,” J. Am. Chem. Soc. 2004, 126, 84-85. Abstract
16 Galliford, C. V; Beenen, M. A.; Nguyen, S. T.; Scheidt, K. A. “Catalytic, Three-Component Assembly Reaction for the Synthesis of Pyrrolidines,” Org. Lett. 2003, 5, 3487-3490. Abstract

Publications as Postdoctoral Fellow and Graduate Student

15 Handa, M.; Scheidt, K. A.; Bossart, M.; Zheng, N.; Roush, W. R. “Studies on the Synthesis of Apoptolidin A. 1. Synthesis of the C(1)-C(11) Fragment,” J. Org. Chem. 2008, 73, 1031-1035. Abstract
14 Evans, D. A; Fandrick, K. R.; Song, H.-J.; Scheidt, K. A.; Xu, R. “Enantioselective Friedel-Crafts Alkylations Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes,” J. Am. Chem. Soc. 2007, 129, 10029-10041. Abstract
13 Evans, D. A.; Scheidt, K. A.; Fandrick, K. R.; Lam, H. W.; Wu, J. “Enantioselective Indole Friedel-Crafts Alkylations Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes,” J. Am. Chem. Soc. 2003, 125, 10780-10781. Abstract
12 Evans, D. A.; Borg, G.; Scheidt, K. A. “Remarkably Stable Tetrahedral Intermediates: Carbinols from Nucleophilic Additions to N-Acylpyrroles,” Angew. Chem. Int. Ed. 2002, 41, 3188-3191. Abstract
11 Scheidt, K. A.; Bannister, T. D.; Tasaka, A.; Wendt, M. D.; Savall, B. D.; Fegley, G. J.; Roush, W. R. “Total Synthesis of (-)-Bafilomycin A1,” J. Am. Chem. Soc. 2002, 124, 6981-6990. Abstract
10 Roush, W. R.; Bannister, T. D.; Wendt, M. D.; Jablonowski, J. A.; Scheidt, K. A.“Studies on the Synthesis of Bafilomycin A: Stereochemical Aspects of the Fragment Assembly Aldol Reaction for Construction of the C(13)-C(25) Segment”, J. Org. Chem. 2002, 67, 4275-4283. Abstract
9 Roush, W. R.; Bannister, T. D.; Wendt, M. D.; VanNieuwenhze, M. S.; Gustin, D. J.; Dilley, G. J.; Lane, G. C.; Scheidt, K. A. ; Smith, W. J. “An NMR Method for Assigning Relative Stereochemistry to β-Hydroxy Ketones Deriving from Aldol Reactions of Methyl Ketones,” J. Org. Chem. 2002, 67, 4284-4289. Abstract
8 Evans, D. A.; Scheidt, K. A.; Downey, C. W. “Synthesis of (–)-Epibatidine,” Org. Lett. 2001, 3, 3009-3012. Abstract
7 Evans, D. A.; Scheidt, K. A.; Johnston, J. N.; Willis, M. C. “Enantioselective and Diastereoselective Mukaiyama-Michael Reactions Catalyzed by Bis(oxazoline) Copper(II) Complexes,” J. Am. Chem. Soc. 2001, 123, 4480-4491. Abstract
6 Scheidt, K. A.; Tasaka, A.; Bannister, T. D.; Wendt, M. D.; Roush, W. R. “Total Synthesis of (–)-Bafilomycin A1: Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions,” Angew. Chem. Int. Ed. 1999, 38, 1652-1655. Abstract
5 Scheidt, K. A.; Roush, W. R.; McKerrow, J. H.; Selzer, P. M.; Hansell, E.; Rosenthal, P. J. “Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors,” Bioorg. Med. Chem. 1998, 6, 2477-2494.
4 Roush, W. R.; Gwaltney, S. L.; Cheng, J.; Scheidt, K. A.; McKerrow, J. H.; Hansell, E. “Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases,” J. Am. Chem. Soc. 1998, 120, 10994-10995. Abstract
3 Scheidt, K. A.; Chen, H.; Follows, B. C.; Chemler, S. R.; Coffey, D. S.; Roush, W. R. “Tris(dimethylamino)sulfonium Difluorotrimethylsilicate, a Mild Reagent for the Removal of Silicon Protecting Groups,” J. Org. Chem. 1998, 63, 6436-6437. Abstract
2 Scheidt, K. A.; Roush, W. R.; Houri, A. F.; La, D. S.; Cogan, D. A.; Hofilena, G. E.; Hoveyda, A. H. “Applications of Zr-Catalyzed Carbomagnesation and Mo-Catalyzed Macrocyclic Ring Closing Metathesis in Asymmetric Synthesis: Enantioselective Synthesis of Sch38516 (Fluvirucin B1),” Chemtracts 1998, 11, 522-530.
1 Miller, M. J.; Darwish, I.; Ghosh, A.; Ghosh, M.; Hansel, J.-G.; Hu, J.; Niu, C.; Ritter, A.; Scheidt, K. A.; Süling, C.; Sun, S. “Design, Syntheses and Studies of New Antibacterial, Antifungal and Antiviral Agents,” Anti-Infectives: Recent Advances in Chemistry and Structure-Activity Relationships, Royal Society of Chemistry Special Publication 1997, No. 198, p. 116-138, Cambridge, UK.

 

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