Developmental Therapeutics at NU

The Center for Developmental Therapeutics (CDT) was established to rapidly and efficiently advance novel therapeutic interventions from basic research to the clinic. The CDT is one of the first academic-based drug development centers that bridges all aspects of translational research in a single entity including early drug discovery, mechanistic research, pre-clinical development and translation into the clinic. Read the rest of our mission here.

The Developmental Therapeutics Core (DTC), under the umbrella of CDT, provides services focused on supporting the translation of new therapeutics to the clinic. See services offered here.

From Bench to Bedside

Since its founding, the Center has facilitated the completion of IND-enabling studies for a homegrown, trial-ready drug to treat acute myeloid leukemia, pre-IND, Phase 0 trials for both Au-NP spherical nucleic acids and apoptosis targeting projects, proof-of concept work for the GSK-3β inhibitor 9 ING-41, and the design and characterization of novel peptides that mimic the function of natural inhibitors of the blood vessel growth (angiogenesis) that cause age-related macular degeneration (AMD).