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Publications

See all publications by Dr. Bass on PubMed

Selected Peer-Reviewed Articles

Weidemann, BJ, Marcheva, B, Kobayashi, M, Omura, C, Newman, MV, Kobayashi, Y, Waldeck, NJ, Perelis, M, Lantier, L, McGuinness, OP, Ramsey, KM, Stein, RW, Bass, J. Repression of Latent NF-kB Enhancers by PDX1 Regulates β-cell Functional Heterogeneity. Cell Metab. 2024 Jan 2;36(1):90-102.e7. doi: 10.1016/j.cmet.2023.11.018

Xia, J, Hepler, C, Tran, P, Waldeck, N, Li, T, Bass, J, Prindle, A. Engineered calprotectin sensing probiotics for IBD surveillance in humans. PNAS. 2023 Aug 7;e2221121120. doi: 10.1073/pnas.2221121120. Epub 2023 Jul 31.

Mihaylova, MM, Chaix, A, Delibegovic, M, Ramsey, JJ, Bass, J, Melkani, G, Singh, R, Chen, Z, Ja, WW, Shirasu-Hiza, M, Latimer, MN, Mattison, JA, Thalacker-Mercer, AE, Dixit, VD, Panda, S, Lamming, DW. When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging. Cell Metab. 2023 Jul 11;35(7):1114-1131. doi: 10.1016/j.cmet.2023.06.008

Ye, Y, El-Haija, MA, Obeid, R, Herz, H, Tian, L, Linden, B, Chu, Y, Guo, DF, Levine, DC, Cedernas, J, Rahmouni, K, Bass, J, Mokadem, M. Reprogramming of the Peripheral Liver-Clock by Gastric Bypass is Associated with an Altered Feeding Rhythm and Changes in Hepatic Glucose Production. JCI Insight. 2023 Feb 14;e166618. doi: 10.1172/jci.insight.166618

Hepler, C, Weidemann, BJ, Waldeck, NJ, Marcheva, B, Cedernaes, J, Thorne, AK, Kobayashi, Y, Nozawa, R, Newman, MV, Gao, P, Shao, M, Ramsey, KM, Gupta, RK, Bass, J. Time-restricted feeding mitigates obesity through adipocyte thermogenesis. Science. 2022 Oct 20;378(6617):276-284. doi: 10.1126/science.abl8007

This paper has been reviewed/profiled in the following editorials:

Marcheva, B, Weidemann, BJ, Taguchi, A, Perelis, M, Ramsey, KM, Newman, MV, Kobayashi, Y, Omura, C, Manning-Fox, JE, Lin, H, MacDonald, PE, Bass, J. P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian b-cell failure. eLife 2022;11:e75132. doi: 10.7554/eLife.75132

Quattrocelli, M, Wintzinger, M, Miz, K, Levine, DC, Peek, CB, Bass, J, McNally, EM. Muscle Mitochondrial Remodeling by Intermittent Glucocorticoid Drugs Requires an Intact Circadian Clock and Muscle PGC1a. Sci Adv. 2022 Feb 18;8(7):eabm1189. doi: 10.1126/sciadv.abm1189. Epub 2022 Feb 18.

Wintzinger, M, Panta, M, Miz, K, Pragasam, AD, Sargent, M, Peek, CB, Bass, J, Molkentin, JD, Quattorcelli, M. Impact of circadian time of dosing on cardiac-autonomous effects of glucocorticoids. bioRxiv. 2021.12.30.474468. doi:10.1101/2021.12.30.474468

Levine, DC, Kuo, HY, Hong, H, Cedernaes, J, Hepler, C, Wright, AG, Sommars, MA, Kobayashi, Y, Marcheva, B, Gao, P, Ilkayeva, OR, Omura, C, Ramsey, KM, Newgard, CB, Barish, GD, Peek, CB, Chandel, NS, Mrksich, M, Bass, J. 2021. NADH Inhibition of SIRT1 Links Energy State to Transcription During Time-Restricted Feeding. Nat Metab. 2021 Dec;3(12):1621-1632. doi: 10.1038/s42255-021-00498-1. Epub 2021 Dec 13.

This paper has been reviewed/profiled in the following editorials:

Kula-Eversole, E, Lee, DH, Samba, I, Yildirim, E, Levine, DC, Hong, HK, Lear, BC, Bass, J, Robash, M, Allada, R. 2020. Phosphatase of Regenerating Liver-1 selectively times circadian behavior in darkness by functioning in PDF clock neurons and dephosphorylating TIMELESS. Curr Biol. 2020 Oct 29;S0960-9822(20)31517-7. doi: 10.1016/j.cub.2020.10.013

Marcheva B, Perelis M, Weidemann B, Taguchi A, Lin H, Omura C, Kobayshi Y, Newman MV, Wyatt EJ, McNally EM, Manning-Fox JE, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. A Role for Alternative Splicing in Circadian Control of Exocytosis and Glucose Homeostasis. Genes Dev. 2020 Aug 1;34(15-16):1089-1105. doi: 10.1101/gad.338178.120. Epub 2020 Jul 2

Levine, DC, Hong, H, Weidemann, BJ, Ramsey, KM, Affinati, AH, Schmidt MS, Cedernaes, J, Omura, C, Lee, C, Braun, R, Lee, C, Brenner, C, Peek, CV, Bass, J. NAD+ Controls Circadian Reprogramming Through PER2 Nuclear Translocation to Counter Aging. Mol Cell. 2020 Apr 24. pii: S1097-2765(20)30236-7. doi:10.1016/j.molcel.2020.04.010. 

Cedernaes, J, Huang, W, Ramsey, KM, Waldeck, N, Cheng, L, Marcheva, B, Omura, C, Kobayashi, Y, Peek, CB, Levine, DC, Dhir, R, Awatramani, R, Bradfield, CA, Wang, XA, Takahashi, JS, Mokadem, M, Ahima, RS, Bass, J. Transcriptional basis for rhythmic control of hunger and metabolism within the AgRP neuron. Cell Metab. 2019 Feb 18. pii: S1550-4131(19)30063-4. doi: 10.1016/j.cmet.2019.01.023. [Epub ahead of print]

This paper has been reviewed/profiled in the following editorials:

Hong, HK, Maury, E, Ramsey, KM, Perelis, M, Marcheva, B, Omura, C, Kobayashi, Y, Guttridge, DC, Barish, GD, Bass, J. Requirement for NF-kB in Maintenance of Molecular and Behavioral Circadian Rhythms in Mice. Genes Dev. 2018 Nov 1; 32(21-22):1367–1379.Published in Advance October 26, 2018, doi:10.1101/gad.319228.118

This paper has been reviewed/profiled in the following editorials:

Peek, CB, Levine, DC, Cedernaes, J, Taguchi, A, Kobayashi, Y, Tsai, SJ, Bonar, NA, McNulty, MR, Ramsey, KM, Bass, J. Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle. Cell Metab. 2016 Oct 19. pii: S1550-4131(16)30490-9. doi: 10.1016/j.cmet.2016.09.010.

This paper has been reviewed/profiled in the following editorials:

Perelis, M, Marcheva, B, Ramsey, KM, Schipma, MJ, Hutchison, AL, Taguchi, A, Peek, CB, Hong, HK, Huang, W, Omura, C, Allred, AL, Bradfield, CA, Dinner, AR, Barish, GD, Bass, J. Pancreatic Beta-Cell Enhancers Regulate Rhythmic Transcription of Genes Controlling Insulin Secretion. Science. 2015 Nov 6; 350 (6261), aac4250 [DOI:10.1126/science.aac4250]

This paper has been reviewed/profiled in the following editorials:

Peek, CB, Affinati, AH, Ramsey, KM, Kuo, SH, Yu, W, Sena, LA, Ilkayeva, O, Marcheva, B, Kobayashi, Y, Omura, C, Levine, DC, Bacsik, DJ, Gius, D, Newgard, CB, Goetzman, E, Chander, NS, Denu, JM, Mrksisch, M, Bass, J. Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice. Science. 2013 Nov 1; 342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19.

This paper has been reviewed/profiled in the following editorials:

Fenner, D, Odili, S, Hong, HK, Kobayashi, Y, Kohsaka, A, Siepka, SM, Vitaterna, MH, Chen P, Zelent, B, Grimsby, J, Takahashi, JS, Matschinsky, FM, Bass, J. Generation of N-ethyl-N-nitrosourea (ENU) Diabetes Models in the Mouse Demonstrates Genotype-specific Action of Glucokinase Activators. J Biol Chem. 2011 Nov 11;286(45):39560-72. Epub 2011 Sep 15.  

Marcheva,B, Ramsey, KM, Buhr, ED, Kobayashi, Y, Su, H, Ko, CH, Ivanova, G, Omura, C, Mo, S, Vitaterna, MH, Lopez, JP, Philipson, LH, Bradfield, CA, Crosby, SA, JeBailey, L, Wang, X, Takahashi, JS, Bass, J. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 2010 Jul 29;466(7306):571-2. 

This paper has been reviewed/profiled in the following editorials:

Arble, D, Bass, J, Laposky, AD, Vitaterna, MH, Turek, FW. Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring). 2009 Nov;17(11):2100-2 [Epub 2009 Sep 3].

Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva, B, Hong, HK, Chong, JL, Buhr, ED, Lee, C, Takahashi JS, Imai SI, and Bass J. Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science. 2009 May 1; 324(5927):651-4 [Epub ahead of print March 19].

This paper has been reviewed/profiled in the following editorials:

Kohsaka, A, Laposky, AD, Ramsey, KM, Estrada, C, Joshu, C, Kobayashi, Y, Turek, FW, Bass, J.  High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab. 2007 Nov; 6(5):414-421; (featured on journal cover)

This paper has been reviewed/profiled in the following editorials:

Turek, FW, Joshu, C, Kosaka, A, Lin, E, McDearmon, E, Laposky, A, Olson, S, Easton, A, Jensen, D, Eckel, R, Takahashi, J and Bass, J. Obesity and metabolic syndrome in Clock mutant mice. Science. 2005 May 13; 308(5724):1043-1045.

This paper has been reviewed/profiled in the following editorials:

Invited Reviews and Commentaries

Bass, J. 2024. Interorgan Rhythmicity as a Feature of Healthful Metabolism. Perspective. Cell Metab. 2024 Feb 8:S1550-4131(24)00009-3. doi: 10.1016/j.cmet.2024.01.009. Online ahead of print. [Available free of charge until March 29, 2024]

Delise, BP, George, AL, Nerbonne, JM, Bass, J, Ripplinger, CM, Jain, MK, Termanstyne, TO, Young, ME, Kannankeril, PJ, Duffy, JF, Goldhaber, JI, Hall, MH, Somers, VK, Smolensky, MH, Garnett, CE, Anafi, RC, Scheer, FAJL, Shivkumar, K, Shea, SA, Balijepalli, RC. 2021. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report from the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations. Circ Arrhythm Electrophysiol. 2021 Nov;14(11):e010190. doi: 10.1161/CIRCEP.121.010190. Epub 2021 Nov 1.

Levine, DC, Ramsey, KM, Bass, J. 2021. Circadian NAD(P)(H) Cycles in Cell Metabolism. Invited Review. Semin Cell Dev Biol. 2021 Jul 16;S1084-9521(21)00195-6. doi:10.1016/j.semcdb.2021.07.008.

Hepler, C, Bass, J. 2021. Supplements to treat prediabetes. Commentary. Science. 2021 Jun 11;372(6547):1147-1148. doi: 10.1126/science.abj0764

Allada, R, Bass, J. Circadian Mechanisms in Medicine. N Engl J Med. 2021;384(6):550-61. doi: 10.1056/NEJMra1802337

Marugan, A, Husain, K, Rust, M, Bass, J, Hepler, C, Pietsch, JM, Swain, PS, Teottcher, JE, Jena, S, Chakraborty, AK, Sprenger, KG, Mora, T, Walczak, A, Rivoire, O, Want, S, Wood, K, Jussell, E, Skanata, A, Ranganathan, R, Hong-Yan, S, Goldfeld, N. Roadmap on Biology in Time Varying Environments. Phys Biol. 2021 Jan 21. doi: 10.1088/1478-3975/abde8d. 

Cedernaes, J, Bass, J. You are when you eat: On circadian timing and energy balance. JCI. 2021 Jan 4;131(1):144655. doi: 10.1172/JCI144655

Weidemann, BJ, Bass, J. Outlook: A Window in Time for Beta-Cell Regeneration. Invited Commentary. Genes Dev. 2020 Dec 1;34(23-24):1559-1561. doi: 10.1101/gad.345769.120

Cedernaes, J, Waldeck, N, Bass, J. Neurogenetic basis for circadian regulation of metabolism by the hypothalamus. Invited Review. Genes Dev. 2019 Sep 1;33(17-18):1136-1158. doi:10.1101/gad.328633.119

Cederroth, CR, Albrecht, U, Bass, J, Brown, SA, Dyhrfjeld-Johnsen, J, Gachon, F, Green, CB, Hastings, MH, Helfrich-Förster, C, Hogenesch, JB, Lévi, F, Loudon, A, Lundkvist, GB, Meijer, JH, Rosbash, M, Takahashi, JS, Young, M, Canlon, B. Medicine in the fourth dimension. Cell Metab.2019 Aug 6;30(2):238-250. doi:10.1016/j.cmet.2019.06.019

Cedernaes, J, Waldeck, N, Bass, J. Neurogenetic basis for circadian regulation of metabolism by the hypothalamus. Invited Review. Genes Dev. 2019 Sep 1;33(17-18):1136-1158. doi:10.1101/gad.328633.119

Weidemann, BJ, Ramsey, KM, Bass, J. A day in the life of chromatin: how enhancer-promoter loops shape daily behavior. Invited Commentary. Genes Dev. 2018 Mar 1;32(5-6):321-323. doi: 10.1101/gad.314187.118.

Bass, J. The circadian clock system’s influence in health and disease. Genome Med. 2017;9:94, doi:/10.1186/s13073-017-0485-2

Bass, J, Lazar, MA. Circadian time signatures of fitness and disease. Invited Review. Science. 2016 Nov 25;354 (6315), 994-999. [doi: 10.1126/science.aah4965]

Perelis, M, Ramsey, KM, Marcheva, B, Bass, J. Circadian Transcription from Beta Cell Function to Diabetes Pathophysiology. Body Clocks Review Series. J Biol Rhythms. 2016 Aug;31(4):323-36. doi: 10.1177/0748730416656949

Cedernaes, J, Bass, J. Decoding Obesity in the Brainstem. eLife 2016;5:e16393. DOI:10.7554/eLife.16393

Bass, J. Targeting Time in Metabolic Therapeutics. Invited Review. Cell Metabolism. 2016 Apr 12;23(4):575-7. http://dx.doi.org/10.1016/j.cmet.2016.03.011

Perelis, M, Ramsey, KM, Bass, J. The molecular clock as a metabolic rheostat. Diabetes Obes Metab. 2015 Sep;17 Suppl 1:99-105. doi: 10.1111/dom.12521

Maury, E, Hong, HK, Bass, J. Circadian Disruption in the Pathogenesis of Metabolic Syndrome. Diabetes Metab. 2014 Nov;pii: S1262-3636(13)00235-8. doi: 10.1016/j.diabet.2013.12.005.

Ramsey, KM, Affinati, AH, Peek, CB, Marcheva, B, Hong, HK, Bass, J. “Circadian Measurements of Sirtuin Biology” in Matthew D. Hirschey, Editor, Sirtuins: Methods and Protocols of Methods in Molecular Biology. Methods Mol Biol. 2013;1077:285-302

Bass, J. Forever (FGF) 21. Invited Commentary. Nature Medicine. 2013 Sept; 19:1090-1092.

Bass, J. Circadian Topology of Metabolism. Invited Insight Review. Nature. 2012 Nov 15;491:348-356

Bass, J. Time in a bottle. Invited Commentary. Nature. 2012 May 2;485(7396):45-6.

Peek, CB, Ramsey, KM, Marcheva, B, Bass J. Nutrient Sensing and the Circadian Clock. Trends Endocrinol Metab. 2012 Jul;23(7):312-8. [Epub ahead of print: Mar 15]. Selected as one of TOP 10 TEM articles of 2012.

Bass, J. Physiology: On time metabolism. Invited Commentary. Nature. 2011 Dec 21;480(7378):466-7

Ramsey, KM, Bass J. Circadian Clocks in Fuel Harvesting and Energy Homeostasis.  Cold Spring Harb Symp Quant Biol. 2011;76:63-72. doi: 10.1101/sqb.2011.76.010546

Huang, W, Ramsey, KM, Marcheva, B, Bass, J. Circadian Rhythms, Sleep, and Metabolism. J Clin Invest. 2011 Jun 1;121(6):2133-41

Marcheva, B, Ramsey, KM, Bass J. Circadian Genes and Insulin Extocytosis. Cellular Logistics. 2011 Jan;1(1):32-36.

Bass, J, Takahashi JS. Circadian Rhythms: Redox Redux. Invited Commentary. Nature. 2011 Jan 27;469: 476–8.

Takahashi, JS, Bass, J. Circadian Integration of Metabolism and Energetics. Science 2010 Dec 3;330(6009): 1349-1354.

Bass, J. High glucose, no cry. Invited Commentary: Nat Med. 2010 Oct;16(10):1152-6.

Maury, E, Ramsey, KM, Bass, J. Circadian Rhythms and Metabolic Syndrome. From Experimental Genetics to Human Disease. Invited Review: Circ Res. 2010 Feb 19;106(3):447-62.

Marcheva, B, Ramsey KM, Affinati, AH, Bass, J. Clock Genes and Metabolic Disease. Invited Review: J Appl Physiol. 2009 Apr;107(5):1638-46. Epub 2009 Aug 6.

Ramsey, KM, Bass, J. Obeying the clock yields benefits for metabolism. Invited Commentary. PNAS. 2009 Mar 17;106(11):4069-4070. [Epub ahead of print March 10].

Green, C, Takahashi JS, Bass, J. The meter of metabolism.  Invited review: Cell. 2008 Sept 5;(134):728-742.

Laposky AD, Bass J, Kohsaka A, Turek FW. Sleep and circadian rhythms: Key components in the regulation of energy metabolism. FEBS Lett. 2008 Jan 9;582(1):142-151.

Moynihan Ramsey, K, Bass, J. Lean gene and the clock machine.  Proc Natl Acad Sci USA 2007 Jun 5;104(23):9553-9554

Moynihan Ramsey, K, Marcheva, B, Kohsaka, A, Bass, J. The clockwork of metabolism. Annu Rev Nutr. 2007;27:219-240.

Kohsaka, A, Bass, J. A Sense of Time: How molecular clocks organize metabolism.  Trends Endocrinol Metab.  2007 Jan-Feb;18(1):4-11.

Bass, J, Turek, FW. Sleepless in America: A pathway to obesity and the metabolic syndrome? Arch Intern Med. 2005 Jan 10;165(1):15-16.

Book Chapters

Cedernaes, J, Ramsey, KM, Bass, J. 2022. “The Role of Circadian Biology in Health and Disease“ in J. Larry Jameson, Sr. Editor, Harrison’s Principles of Internal Medicine, 21st edition, vol.2 (McGraw-Hill Education, 2022), chapter 485, p. 3800-3812 (release date April 15, 2022)

Cedernaes, J, Ramsey, KM, Bass, J. 2018. “The Role of Circadian Biology in Health and Disease“ in J. Larry Jameson, Sr. Editor, Harrison’s Principles of Internal Medicine, 20thedition, vol.2 (McGraw-Hill Education, 2018), p. 3504-3515.

Peek, CB, Ramsey, KM, Levine D, Perelis, M, Bass, J. 2014. “Circadian regulation of cellular physiology” in Amita Sehgal, Editor, Circadian Rhythms and Biological Clocks of Methods in Enzymology (Elsevier, 2014), p. 165-184.

Marcheva, B, Ramsey, KM, Peek, CB, Affinati, A, Maury, E, Bass, J. 2013. “Circadian Clocks and Metabolism” in Martha Merrow and Achim Kramer, Editors, Handbook of Experimental Pharmacology: Circadian Clocks (Springer, 2013), p. 127-155.

Hong, HK, Huang, W, Ramsey, KM, Marcheva, B, Bass, J. 2012. “Clock Genes and Energy Metabolism” in Priyattam J. Shiromani, Tamas Horvath, Susan Redline and Eve van Cauter, Editors, Sleep Loss and Obesity: Intersecting Epidemics (Springer, 2012), p. 13-32.

Maury, E, Ramsey, KM, Bass, J. “Sleep, Circadian Rhythms and Metabolism” in Rexford S. Ahima, Editor-in-Chief, Metabolic Basis of Obesity (Springer, 2011), p. 229-255.

Ramsey, KM, Bass, J. “Animal Models for Disorders of Chronobiology: Cell and Tissue” in Meir Kryger, Editor-in-Chief, Principles and Practice of Sleep Medicine, Fifth Edition (Elsevier, 2010), p. 463-469

Arble DM, Ramsey KM, Bass J, and Turek FW. “Circadian Disruption and Metabolic Disease: Findings from Animal Models”, Best Practice & Research Clinical Endocrinology & Metabolism (Elsevier, 2010), 24(5):785-800.

Kohsaka, A. and Bass, J. “Clock genes and metabolic regulation” in Larry R. Squire, Editor-in-Chief, Encyclopedia of Neuroscience (Oxford: Academic Press, online October 2008), p.1023-1029

Bass, J. and Steiner, DF. “Insulin receptor folding”. In Insulin signaling: from cultured cells to animal models.  (New York: Harwood Academic Presents, 2002) p. 19-35.